Search PubMed⌕ Search

Biomedical subjects

E Halkier

Publications and source records attributed to E Halkier.

At least 19 recordsLinked to original sources
PubMed1994

[Aggressive fibromatosis].

Fibromatosis can be classified in two groups: Superficial fibromatosis without capacity for infiltration and deep fibromatosis with variable capacity for infiltrative growth. One of the deep fibromatoses is aggressive fibromatosis which is a local infiltrating process never known to metastasize. Two cases of aggressive fibromatosis are presented and histological characteristics and prognosis are reviewed. Once the diagnosis aggressive fibromatosis is established, surgical removal of the lesion by large excision is the only sufficient treatment.

Adult↗
PubMed1993

Treatment of primary spontaneous pneumothorax with intrapleural tetracycline instillation or thoracotomy. Follow-up of management program.

Spontaneous pneumothorax has a high incidence of recurrence if treated only with intercostal drainage. A series of 404 patients in a special treatment program is presented. Early thoracoscopy was performed in 97%. The 86 patients (21%) then found to have true cyst (> 2 cm) were subjected to thoracotomy with removal of cyst and mechanical pleurodesis, and in the others a dilute tetracycline solution was instilled intrapleurally, followed by intercostal tube drainage. There was no recurrence of pneumothorax in the group treated with thoracotomy, but 8% recurrence in the tetracycline-treated group. Repeated thoracoscopy was performed in 21 of the 25 patients with recurrent pneumothorax, and thoracotomy with resection of large cyst in four. The probable cause of recurrence was identified in 21 cases, making the true recurrence rate 1% (4 patients). The mean hospital stay was 7.6 days for the patients with thoracotomy and 4.3 days for the tetracycline-treated group.

Adult↗
PubMed1991

[The significance of recurrent nerve paresis for the operability of lung cancer].

The object of the study was a reassessment of the old but still widely accepted apophthegm that recurrent nerve palsy prohibits surgery in patients with pulmonary cancer. Out of 1,279 patients admitted over a 10-year period with proven or suspected pulmonary cancer, 23 were found to have recurrent nerve paralysis. Eleven of these were found inoperable by the preoperative work-up while 12 underwent thoracotomy. In three cases it was possible to perform a left upper lobectomy, which was considered to be radical both macro- and microscopically in two cases. The conclusion is that paralysis of the recurrent nerve, as might be foreseen, gravely worsens the prognosis, inverting the usual ratio of 80:20 between resections and exploratory thoracotomies. This, however, leaves a small group which will benefit from surgery, particularly considering the lack of alternative therapy.

Adult↗
PubMed1989

Changes in pneumonectomy-space gas tensions.

The development of a simple and reliable method for measurement of the partial pressures of the atmospheric gases offers the possibility of both basic and clinical examination of the air in natural as well as pathological or iatrogenic cavities. From measurements in nine patients a plot of the changes in pO2 and pCO2 in the pneumonectomy space from the end of the thoracotomy to the establishment of equilibrium with the blood gases was made. pCO2 equilibrated faster than pO2 (6- and 50 h respectively). The equilibrium difference between arterial pO2 and pneumonectomy space pO2 was 6.5 kPa (2.5-12.3 kPa) and we propose that measuring this difference may be a sensitive method for the diagnosis of bronchopleural fistula. During the study period one of the patients developed a bronchopleural fistula. The suspicion was based on X-ray findings and was supported by gas analysis from the pneumonectomy space, and conclusively confirmed by bronchoscopy.

Adult↗
PubMed1987

[Pneumothorax].

Explore the source record for details and available documents.

Denmark↗
PubMed1987

Pleurodesis in spontaneous pneumothorax by means of tetracycline. Follow-up evaluation of a method.

The validity of previous recommendation of early thoracoscopy and tetracycline pleurodesis in the management of spontaneous pneumothorax without thoracoscopically visualized true cyst was assessed under non-trial, normal hospital conditions. Among 46 patients treated during a year, seven underwent immediate thoracotomy following finding of large cysts. Of the remaining 39 patients, 11 had recurrence of pneumothorax after a median of 11 (range 2-64) weeks. Repeat thoracoscopy then showed large cyst or bullous emphysema in seven cases. Tetracycline pleurodesis was again performed in the others. In continued observation for at least 2 years there were no further recurrences. The importance of meticulous thoracoscopy is stressed. The demonstrated diagnostic errors do not detract from the value of tetracycline pleurodesis when spontaneous pneumothorax is caused by rupture of only tiny blebs on the surface of an otherwise healthy lung. The procedure is fast, simple and efficacious.

Adolescent↗
PubMed1985

Surgical improvement of patients with pulmonary insufficiency due to localized bullous emphysema or giant cysts.

Patients with continuous expansion of either giant lung cysts or areas of localized bullous emphysema will eventually deteriorate into a state of extreme respiratory distress due to compression of the remaining healthy pulmonary tissue. Thirty-one patients with these 2 types of lung disease having very poor respiratory function underwent surgery for the release of compromised healthy lung by resection of the expanding processes. A rational investigation program including respiratory tests, ventilation and perfusion scintigraphy and pulmonary angiography was gradually developed and analyzed. Surgical mortality was 12.9% in unilateral operations, probably somewhat higher in later contralateral interventions. The operative risk was higher in the emphysema group than in the group with giant lung cysts. Follow-up has demonstrated encouraging results in both groups concerning increased pulmonary function as well as improved working capacity.

Adult↗
PubMed1985

Bacterial endocarditis in patients with native or prosthetic heart valves: bacteriological and clinical findings.

The clinical course of 12 episodes of native valve endocarditis (NVE) and 15 episodes of prosthetic valve endocarditis (PVE) was studied. The mortality in NVE was 3/12 episodes and in PVE 5/15. No significant differences in prognosis were observed in relation to the bacterial taxonomy, which was stated in all cases. Though surgical valve replacement was performed on the relative indications heart failure, resistance to treatment, or major embolism, the regimen was primarily conservative, and the results comparable to the reports in the literature of a more surgically active attitude.

Endocarditis, Bacterial↗
PubMed1984

Immediate and long-term results in aortic valve replacement.

In a 12-year period, 127 patients with isolated aortic valve disease underwent valve replacement surgery. Long-term results are presented in regard to patients with operation between 1967 and 1974 and immediate results in the later cases. The main conclusions from the study are that the type of myocardial protection is important for the perioperative mortality rate. This rate was 18% in patients operated on in normothermia and 6% in those with chemical cardioplegia. No significant correlation was found between preoperative NYHA grouping and mortality or complication rate, and the long-term result was independent of the type of valvular prosthesis.

Adolescent↗
PubMed1984

Management of bronchopleural fistula following pneumonectomy.

Bronchopleural fistula developed in 28 (12.5%) of 225 pneumonectomies performed for pulmonary carcinoma of non-small cell types during a 10-year period. The incidence of fistula apparently decreased significantly when chromic catgut was replaced by Dexon for closure of the bronchial stump. The fistula presented as an emergency in nine cases and was subacute in 19. The overall mortality from bronchopleural fistula was 28.6%. Conservative treatment, i.e. bronchoscopic application of silver nitrate to destroy the epithelium in the bronchial stump and induce granulation, achieved closure of fistula in all the surviving patients. In the seven patients with sterile pleural cavity the pleura was not drained. The results justified our principle of conservative management when a bronchopleural fistula does not present as an emergency. In emergency situations, however, or if the pleural fluid is purulent, pleural drainage should be instituted.

Aged↗
PubMed1983

Tetracycline versus silver nitrate pleurodesis in spontaneous pneumothorax.

Silver nitrate pleurodesis as prevention against recurrence in primary spontaneous pneumothorax was started in our department on an empiric basis. In a controlled trial in 1981 the method was found to be as good as earlier stated, but the method has a high number of side effects and has never been widely accepted. In a prospective, controlled trial comparing silver nitrate pleurodesis with tetracycline pleurodesis, we found no differences in recurrence frequency, but the time of hospitalization was significantly longer in the silver nitrate group (p less than 0.05). Furthermore, we found a decrease of exudation and a decreased use of analgetics in the tetracycline group. As a consequence of the investigation, we have abandoned the silver nitrate method and now recommend tetracycline pleurodesis as the treatment of choice in primary spontaneous pneumothorax in patients with only tiny blebs on the surface of the lung.

Adolescent↗
PubMed1983

Mondor's disease: a review of five cases.

Mondor's disease is a superficial thrombophlebitis of the thoracic wall frequently affecting the female breast. In most cases the etiology is unknown, although operation, direct and indirect trauma, are known as causative factors. This material comprises five women, all with Mondor's disease of the breast. One patient did not return for follow-up, in one patient biopsy was performed after 2 weeks. In the remaining three patients the lesion had disappeared after 9 and 10 weeks. Mondor's disease has no relationship to cancer or systemic disease, and no treatment apart from observation is required.

Adult↗
PubMed1982

Pre- and postoperative lung function after pulmonary resection.

For many years, the use of simple spirometric measurements has formed the physiological basis for evaluation of the possible extent of pulmonary resections. Comparison is made between pre-operative and 3-month postoperative spirometric results in patients subjected to enucleation of hamartomas, lobectomies or pneumonectomies. The finding of normal MBC and FEV1 has proven to be a sufficiently safe guideline for surgery and only abnormal MBC or FEV1 are regarded as indicating more extensive pulmonary function studies.

Evaluation Studies as Topic↗