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E H Irigoyen

Publications and source records attributed to E H Irigoyen.

8 recordsLinked to original sources

[Registration with piezoelectric sensors of the in vivo activity of right ventricular contractile elements in acute experimental pulmonary stenosis].

Recordings with piezoelectric sensors of the variations of the contractile state due to severe acute pulmonary hypertension, provoked in intact canine hearts, are described. During the stenosis, a proportional increment of the isometric tension of the right ventricular wall and of the right atrial kick, due to the increasing difficulties for the respective blood contents evacuation of both cavities, were appreciated. Furthermore, lost of the right wall compliance, becoming more rigid, limited the systolic and diastolic pressure development of the right ventricle. Meanwhile, the piezoelectric sensor sutured on the left ventricular wall describes the consequent variations of the left ventricular contraction.

Acute Disease↗

[Recording, with piezoelectric sensors, of the activity of the contractile elements in vivo in experimental acute and chronic aortic stenosis].

Mechanic alterations of the left ventricular wall due to an increasing afterload by means of experimentally provoked acute and chronic aortic stenosis, registered by piezoelectric sensors sutured on the surface of the ventricle, are analyzed. Tension or force developed in the ventricular wall or the acceleration of the shortening velocity of the contractile element, under these conditions, show in the piezoelectric sensor curve a new characteristic contractile state depending on the rapidity and time elapsed since the aortic stenosis, making clear the diagnosis, systolic peaks and their evolutionary stage. Different adaptation mechanisms employed by the myocardium, according to the rapidity of the experimental stenosis, showed by means of the variations of the different phases of the cardiac cycle depicted by sensor curves, are also described.

Animals↗

[Registration with piezoelectric sensors of the normal in vivo activity of the contractile element of the right ventricle].

A new method employed for registration with piezoelectric sensors of the force developed or acceleration of shortening velocity of the contractile element, throughout the right cardiac cycle, is described. The normal activity of the contractile element shows different aspects in both ventricles. SPz curve of the right ventricle is compared with the correspondent SPz curve of the left ventricle. The former curve shows that blood ejection to pulmonary artery is essentially due to developed force or acceleration of shortening velocity of the contractile element, during the isometric contraction phase of the cardiac cycle. Ejection period, with quite constant shortening velocity, seems to complete the blood expulsion. Left ventricular blood flow to systemic circuit is mainly due to early ejection phase, where developed force or acceleration of the shortening velocity of the contractile element appears to be higher, to impulse blood to the aortic artery.

Animals↗

[Human porphyria].

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