Biomedical subjects
Publications and source records attributed to E H Huizing.
High-resolution CT is the method of choice in determining the extent of demineralization in otospongiosis. By comparing the maximum and minimum densities, this examination has become of clinical importance in the diagnostic approach to otosclerosis and in the follow-up of fluorine therapy.
The long term results of our two first cases of septal reconstruction in the acute phase of a septal abscess in childhood are described. Follow-up periods were 19 and 17 years respectively. The development of the nasal pyramid was normal apart from a slight to moderate sagging of the cartilaginous dorsum. Length, width and prominence developed within normal limits and nasal function remained undisturbed. Reconstruction of the septum in the acute phase of a septal abscess seems also on the long term effective in preventing the well known disturbance of growth, form and function of the nose.
Gentamicin-induced cochlear degeneration in the guinea pig was studied by complete hair-cell counting (cytocochleograms) and phase-contrast and interference microscopical examination of the stria vascularis and Reissner's membrane. Gentamicin (100 mg/kg/day) was administered over a period of 7-17 days. The first loss of hair cells (OHC) occurred in a region 6-8 mm from the round window. From this 'degeneration point', the loss of haircells progressed towards the round window (fast) and the apex (slowly). The stria vascularis showed no signs of degeneration. Reissner's membrane, on the other hand, showed intracellular vacuolization of the endolymphatic cells over the complete length of the cochlea after 12 or more days intoxication. Hearing loss was measured by electrocochleography with skin electrodes. The histologic findings were compared with the objective audiograms.
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The long-term histological effects of gentamicin ototoxicity could be studied in a human being in relation to the audiometric impairment. The possible sequence of degeneration of hair cells, supporting cells, nerve fibers, stria vascularis, spiral ganglion cells, and vascular supply is discussed.
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This paper summarizes the author's experience with septum surgery in children from 1963 to 1978. Some 150 children have been operated upon and many of them could be followed up. A septal deformation with breathing problems at rest is an indication for conservative surgery regardless of the patient's age. If there is only breathing difficulty during exercise, other factors (age, external deformity, psyche) play a role in making the decision. Septal deformities without functional complaints are left untouched. The prevention of a growth deformity can be a concomitant factor in deciding whether to operate. Fresh fractures, septal haematoma's and abscesses are undisputable indications for surgery. The surgical technique as used in the two most frequent types of deformation is described. A boy operated upon at the age of 4 was followed-up over a period of 15 years. His nose developed normally until puberty. Then some growth disturbance became apparent.
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Concerning the first description of the so-called tuning-fork test of Rinne the literature refers to a publication by him in 1855. In this work Rinne describes, among many other observations, a method to compare air and bone conduction hearing, and adds the remark that the technique could be used for the diagnosis of deafness. It appears, however, that long before Rinne, Polansky (1842) gave a complete account of the test and its practical use. Polansky's description seems to have been forgotten. Rinne's report, too, was lost for a long period until 25 years later when Lucae (1882) and Schwabach (1885) confirmed the usefulness of the test which - in spite of its earlier discovery by Polansky - has born Rinne's name ever since.
In the third and last part of this study the development of the so-called tuning-fork tests of Schwabach and Bing is discussed. The attention is called to the work of Schmalz (1849), Lucae (1880) and Emerson (1884). These authors preceeded Schwabach (1885) in using and describing the test which became only generally accepted through Schwabach's extensive study and since then bears his name. As to the so-called Bing or occlusion test, Bing's (1891) work is reviewed and the attention is drawn to an early and apparently forgotten description of this test by Rinne (1885).
A technique of wedge resection is used for reduction of an extreme projection of the bony nasal pyramid. In these cases the push-down technique is inadequate, and resection of the dorsum is considered too destructive. The method consists of the resection under direct vision of a bony triangle at the base of the bony pyramid. To this end, a subperiosteal tunnel about 7-8 mm wide is created on the lateral and medial surface of the nasal bones via vestibular incisions.
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