Proceedings: Use of the carcinoembryonic antigen and serum enzyme changes in the detection of metastatic involvement of the liver.
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Biomedical subjects
Publications and source records attributed to E H Cooper.
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The evolution and structure of adenomatous polyps and adenocarcinomata of the colon in NMRI mice induced by dimethylhydrazine are described. Severe toxic reactions in the liver and other organs are produced by dimethylhydrazine (DMH), but tumours are induced only in the colon and around the anus. The 100% incidence and growth characteristics of the tumours make it potentially a good model system, but investigators should take into account the widespread nonspecific cellular injury induced by this carcinogen.
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