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Biomedical subjects

E Grenadier

Publications and source records attributed to E Grenadier.

At least 73 records · Page 4Linked to original sources

Discrete membraneous sub-aortic stenosis in adult patient obtained by echocardiography and not proved by catheterization.

A case of a 60-year-old patient with discrete membranous sub-aortic stenosis is described. The diagnosis was established bases on echocardiographic evaluation by demonstration of a premature aortic valve closure and a sub-aortic membrane. No evidence of the sub-aortic membrane was noticed on cardiac catheterization. At operation, a discrete sub-aortic membrane was found 9 mm below the aortic valve, leaving an aperture of 1 cm diameter and a mildly deformed stenotic aortic valve. We stress the importance of careful pre-operative echocardiographic evaluation of every patient suspected of having any kind of left ventricular outflow tract obstruction, even if catheterization data are not contributory.

Aortic Aneurysm↗

Non oliguric acute renal failure after treatment with sulfinpyrazone.

Two cases with acute reversible renal failure while receiving sulfinpyrazone after acute myocardial infarction are presented. Sulfinpyrazone 200 mg q.i.d. was started a few days after the myocardial infarction. In both patients BUN and creatinine rose significantly, and returned to previous values when the drug was discontinued. No other known causes of renal failure were present in either of the patients.

Acute Kidney Injury↗

Heart block in Marfan's syndrome.

Marfan's syndrome is classified as a heritable disorder of connective tissue in which the supporting structure is involved in clinical and pathologic alterations. In its classic form the syndrome is associated with abnormalities of the eye, aorta, and the skeleton. Conduction disturbances and ventricular arrhythmias have rarely been described in this syndrome. In this brief case report a patient with symptomatic heart block, prolonged atrial-His interval and ventricular arrhythmia in whom a permanent ventricular pacemaker has been implanted, is described.

Adult↗

Prenylamine-induced ventricular tachycardia and syncope controlled by ventricular pacing.

We describe eight patients treated for angina with prenylamine who developed life-threatening ventricular arrhythmias after QT interval prolongation. When prenylamine administration was stopped QT interval shortened to within normal values, while the ventricular arrhythmias were controlled by a temporary ventricular pacemaker and disappeared after several days. We stress the importance of surveillance of the QT interval and ventricular arrhythmias in patients receiving long-term treatment with prenylamine.

Aged↗

Amiodarone-induced thyrotoxicosis: four cases and a review of the literature.

Hyperthyroidism is a rare side effect of amiodarone treatment. Four patients with this untoward effect are described One patient with mild hyperthyroidism before treatment with amiodarone, developed prolonged severe resistant thyrotoxicosis 6 months after initiation of this drug. A second patient with Wolf-Parkinson-White syndrome and paroxysmal atrial fibrillation was successfully stabilized with amiodarone for 18 months. However, the arrhythmia recurred and the thyroid function tests were found to be elevated. In 2 other patients only slight elevation of the thyroid function tests were found without clinical manifestations 4 months after treatment with amiodarone had been initiated.

Aged↗