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Biomedical subjects

E Graziani

Publications and source records attributed to E Graziani.

23 records · Page 2Linked to original sources
PubMedDate not supplied

Prick and intradermal tests compared with specific IgE in allergic assessment.

Allergic assessment in symptomatic patients often requires more tests and they can be conflicting. Sixty outpatients, suffering from seasonal or periannal respiratory symptoms, underwent prick tests, intradermal reactions and specific IgE (IgEs) determination by enzime immunoassay for eight common allergens; in addition total IgE were measured. At the end of the study 512 tests were performed. Total serum IgE levels had no significance in the results. There was a statistically different behaviour among three methods; a positive or negative concordance was found in 64.1% of tests whereas in the others (35.9%) results were conflicting. In particular it was seen that a prick test positive was confirmed by intradermal reaction and a test prick and intradermal negative was not probably confirmed by IgEs. Serum specific IgE levels were higher in subjects prick and intradermal positive than in prick negative and intradermal or IgEs positive subjects. Intradermal reactions were found positive especially in mites and often they were not confirmed by prick or IgEs. So prick test is always the routine test; intradermal test ought to be used if there were prick tests negative and patient's history positive. If prick and intradermal test were found negative it is plausible that the measurement of specific IgE will be negative circumscribing even more the number of individuals where determination of serum specific antibody is necessary.

Humans↗
PubMedDate not supplied

Respiratory allergy to parietaria pollen in 348 subjects.

We have revisited 348 records of allergic outpatients to Parietaria, ratio M/F 1:1 and mean age 29.46 +/- 12.49 yrs. 97 of them were skin positive to Parietaria only (A-group: M/F 37/60); 251 patients were skin positive also to other allergens (B-group: M/F 137/114). Mean age of A-group patients (35.41 +/- 12.91) was higher than B-group (27.16 +/- 11.54; p < 001). Dividing mono and polysensitized subjects by age decade, a different distribution was found between the two groups (p < 001): monosensitized patients showed an increasing number of subjects from the 3rd to the 4th decade and a decreasing trend in the following decades; polysensitized patients showed a prevalence in age < 20 yrs and a decreasing trend in the other decades. In B-group Gramineae were the most frequent allergens associated to Parietaria (84.8%) followed by Olea Europaea (41.1%), Dermatophagoides farinae (37.4%) and Dermatophagoides pteronyssinus (36.2%). Main symptoms were rhinoconjunctivitis (187 cases), rhinitis + asthma (141 cases) and bronchial asthma (20 cases). Comparing the clinical features of the two groups, we have found that monosensitized patients showed a female prevalence, a prevalence of rhinitis with late onset of symptoms while in patients suffering from isolated asthma the onset was early.

Adolescent↗
PubMedDate not supplied

Respiratory allergy to Cupressus sempervirens in Rome.

Mediterranean Cypress pollen is the major aerospore component in winter and early spring. Several recent studies have assessed the incidence of respiratory allergy to this pollen. A personal series of patients encountered in 1994-96 revealed a 9.33% incidence of positive prick-test responses to Cypress pollen among a population with atopical status. That series included 16 (19.05%) single and 68 (80.95%) multiple allergy sufferers. Among the former the symptoms encountered were rhinitis (62.5%) and asthma (37.5%). Given the ever-increasing incidence of Cypress pollen allergy, there is a need to restrict the planting of the tree for ornamental purposes, especially in areas with a high pollen count.

Adult↗