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Biomedical subjects

E Grasso

Publications and source records attributed to E Grasso.

At least 37 records · Page 2Linked to original sources

[Long-term study of 34 cases of subarachnoid hemorrhage not subjected to surgical intervention].

The prognosis of subarachnoid haemorrhage is still a matter of debate. Reference is made to a long-term study of 34 patients not subjected to surgical management. Four recurrences (11.8%), with 3 deaths (8.8%), were noted over a 1-5 yr observation period. A crippling neurological deficiency was noted in 11 subjects (32.2%). The influence of the neurological state in the acute stage on prognosis is discussed.

Adult↗

[Plasma levels of anti-epileptic drugs. Evaluation of determinations carried out in the years 1978-1979].

The results of 701 determinations of antiepileptic drug plasma concentrations administered to 190 patients are described. It has been possible to reduce the number of prescribed drugs to 1.55 per patient, so that only 8.1% of subjects takes three or more drugs while 53% is on monotherapy. The use of the measurement of AEDs plasma concentrations resulted very useful: a) when Phenytoin (PHT) is prescribed; b) in epileptic children; c) when the patient takes two or more drugs; d) to evaluate the compliance. A significant increase (p less than 0.01) of the level/dose ratio of Phenobarbital (PB) when PHT is in, or over, the therapeutic range was observed, while at plasma concentrations of PHT below 10 micrograms/ml it does not influence the metabolism of PB.

Anticonvulsants↗

[Bronchopneumopathies during a course of brucellar infection].

The clinical polymorphism of brucellosis is well known fact. It is thought personally that respiratory system localizations are more frequent than have so far been reported in the literature and serious differential diagnosis problems arise with tuberculosis, neoplasia and pneumoconiosis. After discussing such problems, some cases of pleurobronchopneumopathies during brucellosis which were cured are reported.

Adult↗

[Preliminary study on immunoglobulins G in the cerebrospinal fluid of neurological patients].

The preliminary data from a study of the cerebrospinal fluid IgG of 76 neurological patients are reported. The radial immunodiffusion method was employed. The absolute and percentage increase of IgG with respect to total proteins in the various diagnostic classes involved in the series was considered. The most significant increases were encountered in M.S., in neuropathies and radiculopathies and in tumor involving the subarachnoid spaces. The high percentage is, however, characteristic of M.S. The method is thus particularly useful in diagnosing M.S. and in differentiating it from other neurological diseases.

Brain Neoplasms↗