Origins of catecholamine metabolites in monkey cerebrospinal fluid.
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Biomedical subjects
Publications and source records attributed to E Gordon.
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The Hamilton Rating Scale for Depression is in common use, particularly in durg trials. The authors compared this scale with a system of psychiatric assessment and recording designed by M. Sim. They found that there was closer agreement with the full assessment of the Sim method than with the single diagnostic area for depression. This suggests that the Hamilton Scale for depression is more general than specific in its application.
The authors describe the changing patterns of psychiatric inpatient care in a university hospital. Patients are shortening their hospital stay and are traveling fewer miles from their homes to the hospital. Increasing numbers of blacks, men, and low-income persons are being treated. In addition, the percentage of patients with neuroses and transient situational disturbances has decreased, while the percentage of those with personality and behavior disorders has increased. The authors discuss the implications of these changes, which benefit both patients and the education of students.
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Patients with spinal cord transection had normal concentrations of 5-hydroxyindoleacetic acid and low concentrations of 3-methoxy-4-hydroxyphenyl glycol in lumbar cerebrospinal fluid. The presence or absence of spinal fluid block in these patients did not affect concentrations of either amine metabolite. However, the concentration of homovanillic acid was lower in patients with spinal fluid block than in those without block. The results suggest that the spinal cord contributes to concentrations of 3-methoxy-4-hydroxyphenyl glycol and possibly 5-hydroxyindoleacetic acid, but contributes little to that of homovanillic acid in the lumbar spinal fluid of man.
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