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Biomedical subjects

E Gitsch

Publications and source records attributed to E Gitsch.

At least 73 records · Page 4Linked to original sources
PubMed1982

Prevention of urological complications after radical operation of cervical carcinoma.

Cervical carcinomas of stage Ib and II have been treated for extended radical therapy by radioisotope radical surgery at the First Department of Obstetrics and Gynecology, University of Vienna, Austria. This extension of a more radical surgery requires to take measures in order to prevent urological and other postoperative complications. Chromocystoscopy, intravenous urography and functional scintigraphy of the kidney are carried out as routine preoperative investigations. Preservation of the adureter and an exact drainage of the field of operation are taken as intraoperative measures. Main emphasis of postoperative prophylaxis is the stimulation of ureter activity by distigminbromide and hexoprenaline. Distigminbromide stimulates the prevesical part of the ureter and increases the number of urinary excretions into the bladder. Hexoprenaline is a betamimetic substance which increases both local blood flow and number of ureter contractions. In addition, treatment by antibiotics, thrombosis prophylaxis with heparin and marcoumar and urine drainage by catheter are performed during surgery. The results of 187 radioisotope radical operations show that an uretero vaginal fistula was observed ruly in one patient (0.53%). Hydronephrosis was registered in 10 females (5.3%) and 42 subjects (22.5%) lack of bladder feeling was noted and incontinence was observed in 22 patients (11.8%) in the postoperative period.

Anti-Infective Agents↗
PubMed1982

Prevention of urological complications after radical operation of cervical carcinoma.

Cervical carcinomas of stage Ib and II have been treated for extended radical therapy by radioisotope radical surgery at the First Department of Obstetrics and Gynecology, University of Vienna, Austria. This extension of a more radical surgery requires to take measures in order to prevent urological and other postoperative complications. Chromocystoscopy, intravenous urography and functional scintigraphy of the kidney are carried out as routine preoperative investigations. Preservation of the adureter and an exact drainage of the field of operation are taken as intraoperative measures. Main emphasis of postoperative prophylaxis is the stimulation of ureter activity by distigminbromide and hexoprenaline. Distigminbromide stimulates the prevesical part of the ureter and increases the number of urinary excretions into the bladder. Hexoprenaline is a betamimetic substance which increases both local blood flow and number of ureter contractions. In addition, treatment by antibiotics, thrombosis prophylaxis with heparin and marcoumar and urine drainage by catheter are performed during surgery. The results of 187 radioisotope radical operations show that an uretero vaginal fistula was observed in one patient (0.53%). Hydronephrosis was registered in 10 females (5.3%) and 42 subjects (22.5%) lack of bladder feeling was noted and incontinence was observed in 22 patients (11.8%) in the postoperative period.

Carcinoma↗
PubMed1982

[Intranatal Administration of midazolam (author's transl)].

First experiences with Midazolam during parturition of 109 women show that this drug can help to ease delivery by psychical and muscular relaxation. This results also in a shorter length of the delivery period. Midazolam has a half-life of about two hours and can be applied simultaneously with oxytocin by motor driven syringe. Therefore, the application can be well controlled; and the placenta transfer is small. No fetal or maternal side-effect could be observed other than restricted undulatory amplitudes of the cardiotocogram. Midazolam itself does not exhibit analgetic action, but its application allows to break through the circulus vitiosus anxiety-tension-pain. This results in a reduction of breath depressing analgetics such as Pethidin.

Anesthesia, Obstetrical↗
PubMed1981

[Hypophyseal reaction state during oral contraceptiva (author's transl)].

In 5 normocyclic women, firstly taking a conventional oral contraceptive, Neogynon (50 mcg EE + 250 mcg levo-norgestrel) for 6 months, the levels of LH, 17 beta-E2 and progesterone did not rise after changeover to a dose-reduced pill, Microgynon 30 (30 mcg EE + 150 mcg levo-norgestrel). This fact indicates maintained central suppression. Examination of the hypothalamic-hypophyseal axis by the Gn-RH test (50 mcg) with Microgynon 30 showed negative results during the first treatment cycle in 13 out of 18 women. In the 6th treatment cycle only 7 Gn-RH non-reactive women were observed and after stimulation with 100 mcg Gn-RH only 5 women remained with negative Gn-RH tests. Of the 20 women who took conventional oral contraceptives over a period of 6 months to 6 years (7 took Eugynon: 50 mcg EE + 500 mcg D,L-norgestrel, 5 Lyndiol: 75 mcg mestranol + 2.5 mg lynoestrenol, 8 Neogynon, only one from the Neogynon group showed a positive result. On the other hand there was a positive reaction in 4 out of 7 women using the two step dose-reduced preparation Sequilar (11 tablets of 50 mcg EE + 50 mct levo-norgestrel and 10 tablets of 50 mcg EE + 125 mcg levo-norgestrel).

Adult↗
PubMed1981

Progress in lymphadenectomy potential in radioisotope surgery of cervical carcinoma.

The introduction, in 1969, of radionuclide-assisted radical surgery using colloidal gold resulted in a substantial reduction of mortality from relapses with nodal involvement. While Wertheim's operation practiced between 1961 and 1965 was associated 50% recurrence mortality, mortality for all clinically operable stages dropped to 43.5% between 1966 and 1973, stage Ib mortality decreasing from 47.4% (1961-1965) to 26.9% (1966-1973). Within technetium labeling, which was introduced in 1977, the nodectomy potential was increased from an original 52.5% obtained with 198 colloidal gold and a scanner or eye probe to 88% obtained with the camera technique and technetium in 1979.

Female↗
PubMed1981

[Progress in radio-isotope surgery for cervical carcinoma (author's transl)].

The third phase in the use of radio-isotopes for radical surgery of cervical carcinoma, using 99m Technetium antimony sulphide to localise pelvic lymph nodes on the operating camera table has yielded results which indicate good progress. The potency of lymphadenectomy was increased from an original level of 52.5 per cent to 81.6 per cent. Recurrence mortality went down over the first three years after treatment, according to preliminary results.

Antimony↗
PubMed1980

[The influence of transcerebral impulse current on labour pain and the course of delivery (author's transl)].

107 Patients have been treated by the method of central electrostimulation during delivery. Weak electric current (1,5-3,0 miA) has been applied between fronto-occipital electrodes. In 82% of the patients a sedative effect was observed or reported. A reduction of labour pain took place in 72,8%. An additional effect was the distinct reduction of 50%, concerning the time of labour under this method, compared with a control group of the clinic.

Electric Stimulation Therapy↗
PubMed1980

HPL and estriol serum levels of placental perfusion as indexes of placental function in EPH gestosis and placental insufficiency.

62 patients with EPH gestosis and 64 subjects suffering from placental insufficiency were monitored with estimation of placental perfusion and determination of radioimmunoassayable serum levels of human placental lactogen (HPL) and estriol. The utero-placental blood flow was measured by quick intravenous administration of 0.25-1.0 mCi of (113m)In, and the radioactivity uptake curve was evaluated by a computer program. Good correlation between perfusion type of serum levels of HPL and estriol was recorded. The present data combine to suggest that the recording of utero-placental blood flow is valuable aid in the diagnostic and prognostic evaluation of high-risk pregnancies.

Blood Circulation↗
PubMed1980

LH patterns during clomiphene-induced menstrual cycles.

A total of 409 sterility patients with amenorrhea classified as group II according to the WHO rating scheme were treated with a daily dose of 100 mg of Clomiphene daily for five days in 452 cycles. In addition, 300 infertile subjects with spontaneous cycles (375), but with slight irregularities in the lengths of cycles were included in this investigation as control group. Daily LH serum levels were monitored by rapid solid-phase coated tube RIA. 61.87% of LH single peaks, 28.53% of plateau peaks and 0.53% of double peaks were registered in spontaneous cycles. Similarly, 60.28% single peaks, 23.67% plateau peaks and 0.66% double peaks were registered in Clomiphene-induced cycles. Highest rate of LH plateau and single peaks were found 4 to 6 days and 5 to 7 days, resp., after the end of Clomiphene therapy. No LH peaks were found in 9.07% of spontaneous cycles and in 15.39% of Clomiphene-induced cycles. Data combine to suggest that timing of ovulation by a rapid LH radioimmunoassay is a valuable aid in consulting infertile couples. Failures of patients to conceive must be due to causes other than incorrect timing of ovulation.

Clomiphene↗
PubMed1979

[To the historical development of the abdominal radical operation (author's transl)].

The most important stages in the development of the abdominal radical operation of the carcinoma of the cervix are discussed. These different stages are associated with the following names: Freund and collaboratores; Ries, Rumpf, Clark, Latzko; Wertheim; Bumm; Latzko and Schiffmann; Okabayashi and Meigs. After having reached the limits of the radicality with respect the extirpation of parametrial tissue samples the main emphasis should be the complete lymphonodectomy in the future.

Female↗
PubMed1978

[The development of uteroplacental flow-rate determination (author's transl)].

This paper reviews the technique of nuclear placental flow-rate determination developed in 3 stages at the I. Department of Obstetrics and Gynaecology, University of Vienna. It particularly highlights the diagnostic potential of the most recent development, which is based on iterative regression, by quoting pertinent figures. In 153 females with type I flow-rate patterns the diagnosis proved to be correct in 82.2% of cases. 26 patients had pathological flow-rate patterns and 20 of the infants born to this group of mothers had moderate to severe dystrophy due to reduced placental function. The placental perfusion test, another recent development, is of particular significance in differentiating between the causes underlying reduced placental blood flow. These two techniques have internationally conquered a firm position in the battery of placental perfusion studies designed to assist in the diagnosis and treatment of placental insufficiency.

Blood Flow Velocity↗