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Biomedical subjects

E George

Publications and source records attributed to E George.

At least 127 records · Page 7Linked to original sources

Haemaglobin Bart's in cord blood of Malaysians.

In the newborn the diagnosis of alpha thalassaemia trait is easier because of the presence of haemoglobin Bart's (Hb Bart's). Alpha thalassaemia is common in Southeast Asia. Malaysians are composed of the ethnic groups Malays, Chinese, Indians and Eurasians. Hb Bart's itself is not a simple inherited character but arises from genetically determined imbalance in the biosynthesis of alpha and non alpha chains. 58% of the cord blood samples tested showed raised levels of Hb Bart's. In the Chinese the most common cause of hereditary haemolytic anaemia is haemoglobin H and hydrops foetalis is seen. The rare occurrence of these syndromes in the Malays and Indians in spite of the presence of Hb Bart's indicates an altered expression of the alpha thalassaemia gene in these populations.

Adolescent↗

Immune deficiency in Hodgkin and non-Hodgkin lymphoma.

Forty-three previously untreated Egyptian patients with Hodgkin's disease and thirty-five patients with non-Hodgkin lymphoma were studied with several readily available tests of immune function, number of peripheral blood lymphocytes, delayed hypersensitivity to two recall antigens, in vitro blastoid transformation by PHA, the capacity of E-rosette formation and surface marker criteria. The results were correlated to the histology, stage of disease and to the presence of general symptoms and signs.

Granulocytes↗

Clinical breast examination and breast self-examination experience in a family practice population.

A patient questionnaire, chart audit, and resident questionnaire were used to assess clinical breast examination and breast self-examination experience in a family practice patient population. It was found that approximately 50 percent of the women studied reported annual routine breast examinations during a five-year study period. However, the residency program was responsible for providing or documenting annual clinical examinations in only ten percent of the population. Although 99 percent of the women knew about Breast Self-Examination (BSE), only 19 percent practiced monthly BSE. A positive association was found between the physician's active teaching of BSE and the patient's confidence in and regular practice of BSE. The low number of annual clinical examinations and low performance of BSE may be explained partially by the physician's setting too narrowly the parameters of when a clinical breast examination and BSE teaching could be done appropriately, ie, a pap smear/pelvic or general examination. A more aggressive approach by the physician may increase the number of women who get routine clinical breast examinations and who supplement them by monthly BSE.

Adult↗