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Biomedical subjects

E Geller

Publications and source records attributed to E Geller.

136 records · Page 8Linked to original sources
PubMed1966

Maturation of a stress-activated mechanism inhibiting induction of tyrosine transaminase.

Rats of various ages were subjected to the stress of 30 minutes on a noisy reciprocating shaker 4 hours before their liver tyrosine transaminase and tryptophan pyrrolase activities were measured. Adrenalectomized infants and adults and hypophysectomized adults were also stressed. Intact, stressed infants exhibited an increase in tyrosine transaminase activity, while intact, stressed adults showed no change. In the stressed adrenalectomized adult, tyrosine transaminase activity markedly decreased, while adrenalectomized infants showed no change. Hypophysectomy largely, but not completely, abolished inhibition in the adults. Tryptophan pyrrolase activity, when present, was increased by stress in all age groups, but the increase was abolished by adrenalectomy and hypophysectomy. The results suggest stress-activation of a pituitary mechanism that inhibits or represses activation of tyrosine transaminase and that may not function during early postnatal life.

Adrenalectomy↗
PubMedDate not supplied

Spontaneous pneumoperitoneum without peritonitis.

Spontaneous pneumoperitoneum without peritonitis is a rare phenomenon which poses a dilemma to the surgeon faced with this problem. Two such cases and their outcome are presented. The first case was caused by barotrauma during positive pressure ventilation and was treated by laparotomy. No perforated viscus was found. The second case was caused by tracheal rupture during emergency intubation and was treated by observation until complete resolution. Both patients died for reasons unrelated to the pneumoperitoneum. The mechanisms for passage of air from the chest into the abdominal cavity were through the diaphragm in the first case and along the great vessels in the second. A compilation of other etiologies of pneumoperitoneum without peritonitis as extracted from the literature is presented. In the presence of pneumoperitoneum without peritonitis and when the clinical history does not suggest perforation of a viscus, we advise performing an abdominal tap. If negative, continued observation is advised.

Aged↗