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Biomedical subjects

E Gazit

Publications and source records attributed to E Gazit.

209 records · Page 12Linked to original sources
PubMedDate not supplied

Cost-benefit analysis of a national screening programme for cystic fibrosis in an Israeli population.

The recently acquired ability to identify 97% of CF carriers in an Israeli Ashkenazi population, prompts an evaluation of a nationwide screening programme. In 1993, the programme would first screen and counsel 9,261 parents, then 396 spouses of carrier parents and finally screen 16.5 fetuses where both parents are carriers. Assuming 92% of screened parents choose abortion of fetus screened positive, 2.33 cases of CF will be prevented in 1993 at a direct cost of $781,000. The $326,000 direct costs of preventing a CF case, exceed the lifetime excess direct costs per case of $297,000. However, benefits of screening also accrue to subsequent pregnancies, resulting in a direct benefit ($14.45 million) to cost ($10.39 million) ratio of 1.39/1 for the period 1993-2032. When benefits and costs resulting from mortality changes, work absences and transport costs are included, the benefit ($15.95 million) to cost ($13.88 million) ratio falls to 1.15/1. Benefit-cost ratios are lower for other ethnic groups in Israel, due to lower carrier rates and lower mutation detection abilities. A CF screening programme will increase the freedom of individuals choice, but should be carried out carefully in order to minimize stigmatization and even discrimination against CF carriers.

Abortion, Eugenic↗
PubMedDate not supplied

Integrated electromyography of the masseter on incremental opening and closing with audio biofeedback: a study on mandibular posture.

PURPOSE: The purpose of this study was to test the hypothesis of a minimum electromyographic (EMG) rest position based on masseter surface EMG recordings of incremental opening and closing of the mandible with simultaneous audio EMG biofeedback. MATERIALS AND METHODS: Nineteen alert subjects in an upright seated position opened and closed the mandible in 1-mm increments 20 mm interincisally. An electronic recording device allowed each subject to maintain the vertical dimension of each increment while simultaneously reducing right masseteric muscle activity to the minimum possible level using audio EMG biofeedback. Integrated EMG masseteric activity was recorded at each static opening and closing increment. RESULTS: A mean plateau of integrated EMG output for all subjects with no minimum EMG point or circumscribed minimum EMG range for any of the nineteen subjects was shown. Analysis of variance for repeated measures showed no difference in opening and closing EMG levels (P = 0.27) and no interaction between opening, closing, and change in vertical dimension (P < 0.0001). CONCLUSION: These results, with those of other studies, raise questions regarding the validity of the concept of a unique physiologic rest position of the mandible with the masseter or associated muscles at minimum muscle activity. The idea of overlapping postural ranges appears to be more appropriate.

Adult↗
PubMedDate not supplied

Timing of orthodontic tooth movement in a case with traumatized and avulsed anterior teeth.

A traumatic injury to a patient undergoing orthodontic treatment resulted in avulsion, dislodgement, and fracture of upper anterior teeth. Deciding when to institute endodontic treatment and when to resume orthodontic treatment was based upon minimizing the changes for ankyloses and root resorption. Endodontic treatment was carried out two weeks after trauma, and orthodontic treatment continued three weeks after trauma. Radiographs taken six months, one year, and two years after orthodontic completion showed progressive root resorption to the avulsed tooth and minimum root resorption to the remaining anterior teeth.

Adolescent↗
PubMedDate not supplied

Noses, tongues, and teeth.

There is a renewed interest in the relationship between breathing patterns, tongue positions, and orthodontic management of patients with malocclusion. The authors address the effects of these factors on arch-form and occlusal contacts.

Child↗