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Biomedical subjects

E Gardner

Publications and source records attributed to E Gardner.

At least 145 records · Page 8Linked to original sources
PubMed1992

Computer system RFPs: long form vs. short form.

Requests for proposal, the thousand-page tomes hospitals write when shopping for a new computer system, evoke an array of emotions. Some hate them, saying they're too long, too expensive to answer and leave too many false impressions. Others like them, saying RFPs are valuable, especially as an organizational tool. Some hospitals say they have the answer--a more focused approach.

Competitive Bidding↗
PubMed1992

Ferranti talks to potential buyers after Chapter 11 bankruptcy filing.

More than 500 nursing facilities and 26 hospitals that rely on the financial software of Ferranti Healthcare Systems Corp. are wondering what will happen now that the company filed for protection from creditors under the Federal Bankruptcy Act. Ferranti executives say they're talking to several potential buyers.

Bankruptcy↗
PubMed1992

1992 healthcare business outlook.

Whether it's with apprehension or expectation, most of us are wondering what the new year will hold. With that question in mind, Modern Healthcare staff writers and healthcare industry leaders offer their short- and long-range forecasts for all sectors and on a variety of all-encompassing issues. Some key questions: Will presidential politics pressure healthcare reform efforts? How will investor-owned companies fare under another year of regulatory scrutiny? What awaits hospitals and physicians under the new fee schedule and other Medicare rule changes?

Attitude of Health Personnel↗
PubMed1992

JCAHO's 'Agenda for Change' to place new demands on systems.

The Joint Commission on Accreditation of Healthcare Organizations hasn't told hospitals enough about the new demands that its "Agenda for Change" will place on hospitals' information systems. Hospitals will have to be able to abstract medical records electronically and analyze their data to fully benefit from the program, executives at one test site say.

Costs and Cost Analysis↗
PubMed1992

Complementary physical and genetic techniques map the vinculin (VCL) gene on chromosome 10q.

Vinculin is a cytoskeletal protein component of adherens type cell junctions. The gene had been mapped to 10q11.2-qter. We have used a combination of physical and genetic mapping techniques to refine this localization. Hybridization of the vinculin cDNA probe, HV1, to a human-rodent somatic hybrid panel initially suggested a position of either 10q11.2 or 10q22.1-10q23. Genetic recombination mapping in three-generation families with multiple endocrine neoplasia type 2 (MEN2) indicated a position distal to D10S22 (10q21.1) in 10q22.1-10q23. This was confirmed by hybridization of the vinculin cDNA to flow-sorted translocation derivative chromosomes containing the q21-qter portion of chromosome 10. We conclude that the vinculin locus maps in 10q22.1-q23, distal to D10S22.

Animals↗
PubMed1992

A preliminary analysis of consortium data for markers tightly linked to multiple endocrine neoplasia type 2A.

We have analyzed DNA marker typing data contributed by six independent groups to estimate the pairwise genetic distances between these markers and the locus for multiple endocrine neoplasia type 2A (MEN 2A). We used LIPED to calculate these distances for female, male, and sex-average linkage maps and to determine the corresponding LOD scores. The preliminary analyses of this large data set (89 MEN 2A families and five non-MEN 2A references families, with 1,934 total individuals) are reported here. These refined estimates of the genetic map in this region will aid in the assignment of presymptomatic diagnoses. This study clearly points out the limitation of pairwise linkage analysis in further refining the position of MEN2A in this small region of chromosome 10. Further refinement of the genetic map position of MEN2A will be best accomplished by finding, verifying, and accurately mapping crossovers in specific families.

Chromosome Mapping↗