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Biomedical subjects

E Galun

Publications and source records attributed to E Galun.

118 records · Page 7Linked to original sources
PubMed1969

Complementation in nonconidiating mutants of Trichoderma.

Nonconidiating (Con(-)) mutants were isolated from wild-type and color mutants of the fungus Trichoderma viride Pers. ex Fries. Heterokaryons were easily produced and maintained, and the complementation relationships among the Con(-) mutants were established. Most Con(-) mutants could complement one or more of the other Con(-) mutants. When marked Con(-) mutants were mixed with marked Con(+) testers, conidiating heterokaryons were formed. The conidia thus obtained produced only the parental type colonies after replating, indicating that nonconidiation is a nuclear characteristic. Allowing two Con(-) colonies to meet and produce a heterokaryon, it was found that the migration of nuclei reached a rate of 5 mm per hr, which is several times greater than the rate of hyphal elongation; it was also found that heterokaryosis of a mycelial region preceded its ability to conidiate.

Genetics, Microbial↗
PubMed1966

Morphogenesis in Trichoderma: suppression of photoinduction by 5-fluorouracil.

Sporulation in the fungus Trichoderma viride is inducible with a short light pulse. 5-Fluorouracil applied prior to photoinduction and removed thereafter suppressed sporulation without greatly aflecting growth. This compound also halved the rate of incorporation of uracil-C(14) into RNA but did not change the ratio of uridylic to cytidylic acid. The effect of 5-fluorouracil was counteracted by uracil but not by thymidine. This supports the hypothesis that 5-fluorouracil affects RNA rather than DNA.

Carbon Isotopes↗
PubMedDate not supplied

Granulocytic sarcoma (chloroma) of bone: the CT appearance.

Granulocytic sarcoma (chloroma) is an unusual tumour usually seen in cases of myelogenous leukemia. The tumour is most commonly located in the skull, orbits and sinuses. Extracranial tumours occur mainly in the soft tissues of the body and bone involvement is uncommonly seen and is almost invariably lytic in nature. We describe the first case of CT demonstration of bone involvement by such a tumour. A mixed sclerotic and lytic pattern was seen.

Adult↗