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Biomedical subjects

E G Zook

Publications and source records attributed to E G Zook.

At least 37 records · Page 2Linked to original sources

Fingernail deformities secondary to ganglions of the distal interphalangeal joint (mucous cysts).

Twenty-six nail deformities secondary to ganglions of the distal interphalangeal joint were retrospectively reviewed to assess the important aspects of their management. The patients' ages ranged from 41 to 79 years. The long and index fingers were most commonly involved. A depression or groove was present in 23 of 26 digits reviewed. Two had gross disruption of the nail. Fifty-eight percent of the cysts had spontaneously drained or had been drained by the patient or a physician preoperatively. Degenerative arthritic changes were seen in 87 percent of those with x-rays or a radiology report available. Most underwent surgical removal of the cyst and debridement of associated osteophytes of the distal interphalangeal joint. The cyst was located above the germinal matrix in all but two digits. Osteophytes were found in all 20 digits in which the joint was explored. No recurrences were seen in those available for postoperative follow-up (22 of 25). Normal nail growth was found in 14 of 22, although follow-up was short in one. All eight postoperative nail deformities were quite mild and of little concern to the patient. There was no correlation between preoperative cyst drainage and aesthetic postoperative nail growth. Nail removal at the time of surgery appeared to be unnecessary unless the nail was grossly disrupted.

Adult↗

The extended pectoralis major myocutaneous flap: uses and indications.

The vascular territory of the pectoralis major muscle and overlying skin was studied by selective intraarterial dye injections in fresh cadavers. The area of skin overlying the anterior chest and abdominal wall beyond the limits of the pectoralis major muscle that can be elevated as an extended myocutaneous flap was determined. The cadaver injections were evaluated to determine the size and shape of the skin island used to reconstruct defects of the head, neck, and upper trunk with an extended skin paddle off the pectoralis major muscle. Pectoralis muscle flaps with variously shaped skin paddles, some extending beyond the limits of the muscle, were used in 27 patients to cover large soft-tissue defects of the upper thorax, face, and floor of the mouth and as a skin tube to reconstruct the cervical esophagus. The size of the skin paddle ranged from 5 x 7 cm to 26 x 16 cm. All flaps survived completely, and there were no major donor-site complications.

Adult↗

Leaving the fold.

Explore the source record for details and available documents.

Faculty, Medical↗

Malignant acrospiroma.

A 76-year-old woman was referred after results of the biopsy of an ulcerated mass of the right long finger suggested poorly differentiated squamous cell carcinoma. Excision and skin grafting were done and a diagnosis of malignant acrospiroma was established. These tumors are aggressive and 5-year survival rate may be as low as 30%. A ray amputation was subsequently done and the specimen was without residual tumor. At 14 months follow-up, the patient remains free of disease.

Adenoma, Sweat Gland↗

Anatomy and physiology of the perionychium.

It is essential that practitioners, especially surgeons, understand the anatomy and physiology of the tissues they are treating. It is especially important in the nail bed because most practitioners know little about the specific anatomy and physiology of the nail bed. Only if such information is known and considered can new techniques and research in the anatomy, physiology, and care of the nail bed be used. In addition to the individual parts of the nail bed, developmental physiology, embryology, vasculature, lymphatics, and nerve supply are discussed.

Humans↗

Reconstruction of a functional and esthetic nail.

The most common cause of nail bed deformity is trauma, but other causes are infection, tumor, ischemia, or congenital anomalies. This article includes discussions of nonadherence, split nail, reconstruction of the eponychium, crooked and hooked nail, bony irregularity, pachyonychia, ischemic deformities, and absence of the nail. New problems are encountered daily and other deformities have no method of correction recorded in the literature. For these cases, we provide suggested treatments based on the anatomy and physiology of the nail.

Amputation, Traumatic↗

Sural nerve grafts for delayed repair of divided posterior interosseos nerves.

Sural nerve grafts were used in three patients to bridge gaps measuring 2 1/2 to 4 1/2 cm in previously transected but not repaired posterior interosseous nerves. The grafts were done at 4, 5, and 7 months after injury. Extension was weaker in all three than on the uninjured side, but the range of motion was complete, with the exception of a slight lag of index finger extension and partial return of extension of the extensor carpi ulnaris in the same patient. All three patients recovered full function of the involved hand 1 year after grafting. The properties of the posterior interosseous nerve (pure motor and short distance to the muscle) contribute to good results with nerve grafts in delayed nerve repairs. We believe that these results are better than tendon transfers, at least in young patients.

Adolescent↗

V-Y advancement flaps for tumor excision defects of the eyelids.

Resection of cutaneous malignancies of the medial canthus and lower lid create challenging wound closure problems. The V-Y flap closure technique achieves wound closure using adjacent tissue while minimizing closure tension. Twenty-three patients underwent resection of basal cell carcinomas in these two anatomical regions. In 22 patients a single V-Y flap was used to close the defect. In 1 patient two flaps were used. There were 2 patients with transient ectropion. No tissue loss or other complications occurred.

Basal Cell Carcinoma↗

V-Y advancement flaps for closure of nasal defects.

The nose is a difficult anatomic region in which to close defects resulting from resection of cutaneous malignancies. The V-Y flap is a technique for advancing adjacent tissue, thereby achieving wound closure while minimizing tension. A total of 120 V-Y flaps were used to close 114 nasal defects. The average defect size was 13.5 x 11 mm. Partial flap loss occurred in five patients, with total flap loss in one. One wound infection and two hematomas occurred.

Basal Cell Carcinoma↗

Palmar wrist pain caused by ulnar nerve entrapment in the flexor carpi ulnaris tendon.

A 38-year-old female nurse was seen initially with several years' history of recurring intermittent ulnar wrist pain and paresthesias. The pain was aggravated by specific tasks using her hands, such as typing. Splinting and two steroid injections into the area gave only temporary relief. Surgical exploration revealed a segment of the ulnar nerve composing approximately 15% of its volume to split from the main trunk of the ulnar nerve, perforate the flexor carpi ulnaris tendon, and then rejoin the ulnar nerve. The nerve branch was extracted from the flexor carpi ulnaris by dividing approximately 15% to 20% of the tendon, allowing the nerve to be removed from the perforation, and anatomically relocated. The patient resumed her normal activities and has had no further discomfort in her wrist.

Adult↗

Management of fingertip trauma.

Sound knowledge of fingertip anatomy and of the potential for long-term morbidity are essential in formulating an organized approach to fingertip injuries. An accurate assessment of the deficits created by the injury is then possible. The goal of treatment is to re-create normal anatomic relationships as closely as possible. Many fingertip injuries are easily managed by a nonspecialist. However, more complex procedures, such as the use of local or distant flaps, is beyond the realm of most primary care physicians, and appropriate referral to a hand specialist may be required.

Amputation, Traumatic↗

Experimental evaluation of the antibiotic carrying capacity of a muscle flap into a fibrotic cavity.

A study was undertaken to determine the antibiotic carrying capacity of a transferred muscle flap into a fibrotic cavity using a tissue cage model in rabbits. Blood and chamber fluid antibiotic levels were determined after intramuscular hindlimb gentamicin injection up to 56 days following muscle transfer. This study suggests that muscle flaps increase the concentration of antibiotics that can be achieved within a fibrotic cavity. The measurable peak level decreases with time, probably due to increased scarring around the muscle. This model should enable the study of many different classes of antibiotics with different protein binding and other administration schedules using multiple timed doses or a combination of agents.

Animals↗

Altered spatial perception following harvest of a posterior auricular skin graft.

A 57-year-old man blind since an early age lost significant ability to orient himself in space regarding surrounding objects after his left ear was retropositioned to close a retroauricular full-thickness skin graft donor site. Release of the ear to its former position corrected the disability. We warn readers that long-time blind persons develop alternate methods to vision and a seemingly insignificant change of ear position may alter spatial orientation.

Blindness↗

Experimental pretransfer expansion of free-flap donor sites: II. Physiology, histology, and clinical correlation.

There is a statistically significant increase in blood flow into expanded cutaneous and myocutaneous flaps in a pig model over controls. The vascular trees within flaps enlarge following expansion, and pronounced neovascularization is seen in the papillary dermis and capsular layers. Experimentally, there is differential thinning of all tissue layers except the epidermis. A successful clinical application of this technique, by free-tissue transfer of an expanded fasciocutaneous scapular flap, is described. The technique is applicable when altered flap size or contour is desired.

Adipose Tissue↗

Experimental pretransfer expansion of free-flap donor sites: I. Flap viability and expansion characteristics.

Expansion of cutaneous and myocutaneous free-flap donor sites prior to elevation is possible in the pig model. There is no significant difference in survival between control and expanded cutaneous buttock and myocutaneous latissimus dorsi flaps after elevation solely on their axial pedicles. Axial-pattern flap expansion appears to augment capillary blood flow. The maximum amount of expansion occurs directly over the center of the expander and decreases toward the periphery. There is virtually no expansion of skin adjacent to the expander.

Animals↗

Glutaraldehyde-treated autogenous skin as a substitute for elastic cartilage: an experimental study.

In an experimental study in rats, a piece of dorsal skin was removed, molded, and tanned in glutaraldehyde. After rinsing in saline, the piece of skin was tested for extensibility and implanted under the dorsal skin of the same rat. It was removed after 1 to 12 weeks and its extensibility was again measured. Specimens were examined under the light and electron microscopes. None of the 63 implants extruded and at 12 weeks a thin, densely adherent fibrous capsule had formed. Light and electron microscopy revealed early inflammatory changes that later subsided. The implant maintained or increased its stiffness. The weight of the implant remained constant.

Animals↗

Management of acute facial powder burns.

To evaluate the management and outcome of acute facial powder burns, 10 patients admitted to a burn center (1980-1985) were reviewed. Facial burns resulted from black gun-powder in 7 and fireworks in 3 patients. Most burns occurred in teenage boys (6) and all but 1 were the result of carelessness on the part of the burn victim. While most facial burns were treated conservatively, 2 patients sustained traumatic tattooing and underwent immediate debridement using a variety of surgical techniques in sequence. Good aesthetic results were obtained and the details of this approach are presented.

Adolescent↗