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E G Starostina

Publications and source records attributed to E G Starostina.

At least 19 recordsLinked to original sources

[How physicians and patients look at the problem of obesity].

AIM: To elicit attitude of physicians and population to the problem of obesity; to assess awareness and diagnostic and therapeutic tool. MATERIAL AND METHODS: A questionnaire survey was performed among 384 endocrinologists and 54 other medical professional in 13 cities of Russia. 1405 randomly selected citizens of Moscow (males and females) aged 18-64 years were interviewed according to the standard questionnaire on the telephone. THE RESULTS: Opinion of the physicians. Endocrinologists think that the key factors of weight gain are the following: overeating (81%), hypodynamia (53%), heredity (36%), endocrine pathology (20%), diet rich in fat (18%). Body weight is assessed on the basis of BWI (80%), weight-height tables (38%), Brock's formula (25%), waist and hip circumferences (21%). Endocrinologists believe that obesity should be treated to improve wellbeing (75%), concomitant syndromes (53%), appearance (4%). 92% of endocrinologists recommend a low-calory diet, 82%--physical exercise, 15%--medication, 6%--food additives. Potential patients. 1/3 of city population have overweight. 1/4 of them want to lose weight. Women want to lose weight three times more frequently than men. The proportion of men and women wanting to lose weight is higher at the age group of 40-49 years. Obese subjects more frequently than subjects with normal weight want to lose weight without keeping diet (53 vs 39%) or extra physical activity (38% vs 27%). Women more frequently use methods of losing weight (both registered and unregistered). CONCLUSION: Physicians underestimate the role of obesity in genesis of concomitant diseases, the role of high-calory diets in development of obesity. Most of potential patients have an inadequate attitude to the necessity and feasibility of weight loss, are unrealistic as to methods of losing weight and effectiveness of such methods.

Adolescent↗

Effectiveness and cost-benefit analysis of intensive treatment and teaching programmes for type 1 (insulin-dependent) diabetes mellitus in Moscow--blood glucose versus urine glucose self-monitoring.

In a prospective controlled trial the effects of a 5-day in-patient treatment and teaching programme for Type 1 (insulin-dependent) diabetes mellitus on metabolic control and health care costs were studied in Moscow. Two different intervention programmes were compared, one based upon urine glucose self-monitoring (UGSM, n = 61) and one using blood glucose self-monitoring (BGSM, n = 60). Follow-up was 2 years. A control group (n = 60) continued the standard treatment of the Moscow diabetes centre and was followed-up for 1 year. Costs and benefits with respect to hospitalizations and lost productivity (according to average wage) were measured in November 1992 rubles (Rb.), with respect to imported drugs and test strips in 1992 German marks (DM). In the intervention groups there were significant decreases of HbA1 values [UGSM: 12.5% before, 9.4% after 1 year, 9.2% after 2 years (p < 0.0001); BGSM: 12.6% before, 9.3% after 1 year, 9.2% after 2 years (p < 0.0001) compared to no change in the control group (12.2% before, 12.3% after 1 year)], and of the frequency of ketoacidosis. The frequency of severe hypoglycaemia was comparable between the UGSM (10 cases during 2 years), BGSM (10 cases during 2 years), and the control group (8 cases during 1 year).(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

Effect of training on the performance of blood glucose monitoring using a reagent strip (Glucoprofil).

A relatively simple, new test-strip for blood-glucose monitoring, the Glucoprofil strip with a reaction-zone of film-foil, was evaluated by testing 100 different blood glucose concentrations between 2.1 and 29.7 mmol/l. The results were obtained visually before and after training to read the color changes of the strip according to the scale on the strip-container. Plasma glucose measurements with the Beckman Glucose-Analyzer were used for reference. The results show that the Glucoprofil-strip readings correlated well with the reference method (r = 0.97), thorough training provided. The mean deviation of the strip results was less than 1 mmol/l. Similar results were obtained using another blood glucose strip, the Haemoglukotest 20-800 R. Our study indicates that the performance of the Glucoprofil strip is satisfactory, and hence the strip may be useful for clinical purposes. Consistent with previous reports we could demonstrate that training improved the reading results of the Glucoprofil strip.

Blood Glucose↗

[Experience in the use of biostator in the treatment of diabetes mellitus in children of the pubertal age].

The authors discuss the possibilities of the use of the apparatus "artificial pancreas biostator" in multiple modality treatment of patients suffering from type I diabetes. The own research data are provided. They are based on the use of the apparatus "biostator" in 62 children aged 9-15 years with diabetes mellitus in order to improve insulin therapy. After treatment sessions with the aid of the apparatus all the patients noted improvement of the well-being and abatement of the signs of diabetes mellitus lability. In some cases, the treatment using the apparatus promoted a more rapid attainment of disease compensation as compared to the application of conventional treatment methods. It has been shown that high insulin requirement of pubertal children with diabetes decompensation is determined in many respects by activation of the hypothalamus-pituitary-adrenal system.

Adolescent↗

Diabetes education in the USSR: how to begin?

To determine patients' attitudes towards diabetes education in the Soviet Union, a questionnaire was distributed throughout the country. From 10,000 completed forms, returned from all regions of the USSR, 2000 were analysed in detail. Responders represented all age and social groups, but patients with shorter duration of diabetes, and women, responded more readily. More than 41% of patients were unaware of the type of diabetes they had, the actual proportions of Type 1 and Type 2 diabetes among respondents being 31 and 63%. Rates of chronic complications derived from patients' answers suggest a high rate of underestimation by local physicians. Only 17% of Type 1 and 8% of Type 2 diabetic patients believed that they knew enough about diabetes, and 99.9% of all respondents wanted to learn more about their disease. Independently of the type of diabetes and educational level, patients would accept the information on diabetes from periodicals (63-68%), television (48-63%), booklets for patients (29-31%), as well as attending diabetes courses or classes (30-38%). They expressed preference for teaching conducted by physicians (74-85%) rather than nurses (1-4%). The main areas of interest for Type 1 diabetic patients were technical devices, (artificial pancreas and insulin pumps (85%] and late diabetic complications (78%), and for patients with Type 2 diabetes late complications (84%) and diet (72%). Some respondents (20-25%) expected the use of herbs and other 'non-traditional' methods to be effective in treatment and curing of diabetes. The least requested topics were acute complications (18-34%) and metabolic self-monitoring (0.025%).(ABSTRACT TRUNCATED AT 250 WORDS)

Attitude to Health↗

[Relationship between glucose utilization by tissues and residual insulin secretion and their role in the genesis of hyperglycemia in type I diabetes mellitus].

Altogether 67 patients aged 16 to 50 suffering from insulin dependent diabetes mellitus (IDDM) of various duration were investigated to study the effect of peripheral sensitivity to insulin on genesis to hyperglycemia in type I diabetes mellitus. Residual beta-cell insulin secretory function was assessed by the level of C-peptide in a standard food test, and the rate of glucose utilization by tissues was studied by the clamp-method under the conditions of normoglycemia. The results obtained indicate the role of a decrease in peripheral sensitivity to insulin in genesis of hyperglycemia in diabetes mellitus, type I, and the presence of reciprocal interactions between glucose utilization and insulin secretion in IDDM patients and in controls.

Adolescent↗

[Sensitivity to insulin studied by the clamp method in patients with type-1 diabetes mellitus].

The rate of insulin dependent utilization of glucose by tissues under the conditions of normoglycemia was assessed in 76 patients with insulin dependent diabetes mellitus (their age and period of disease varied) without clinical signs of resistance to insulin. The investigation was performed with the help of the clamp method. A decrease in the sensitivity to insulin was noted even in normal values of carbohydrate and fat metabolism. A decrease in the insulin dependent rate of glucose utilization by tissues depended neither on sex and age of the patients, nor on a period of disease, body mass, daily requirement in insulin, the levels of cholesterol, triglycerides and ketone bodies. A transient increase in the rate of glucose utilization during the 1st year of disease was typical of patients with partial remission. It has been assumed that a decrease in the sensitivity to insulin in insulin dependent diabetes mellitus cannot be the secondary metabolic phenomenon only.

Adolescent↗

[Use of the monopeak insulin drugs "insulrap" and "insulong" in the treatment of type I diabetes mellitus].

A study was made of the effectiveness of the use of new monopeak insulin drugs of short-term and prolonged action in therapy of 30 patients with type 1 diabetes mellitus. The effect of the drugs was estimated during a follow-up (1-6 mos.) by the parameters of carbohydrate metabolism and the time course of serum insulin binding capacity as well as by change in a dose of insulin as compared to that of the common Soviet drugs of the insulin-zink-suspension (IZS) group and monopeak drugs of the Long group. The drugs under study were shown to be no inferior to the monopeak drugs of the Long group and in some cases superior to the drugs of the IZS group. A significant decrease in the titer of antibodies to insulin against a background of therapy was unnoticed. Positive and negative qualities of both drugs (Insulrap and Insulong) were discussed.

Adolescent↗

[The insulin and proinsulin levels in patients with newly detected diabetes mellitus].

Total immunoreactive insulin (IRI), proinsulin-like component, IRI, C-peptide and glucagon were determined in patients with newly detected diabetes mellitus and in healthy subjects on an empty stomach and after food testing. The results obtained have shown that a study of the serum total IRI composition combined with C-peptide determination during food testing can be used as a diagnostic test to define a type of diabetes mellitus.

Adolescent↗

[Combined use of automatic systems for treating patients with type 1 diabetes mellitus].

The efficacy of the combined consecutive use of the apparatus "Artificial Pancreas" (Biostator) and portable dosing apparatuses of insulin (Microjet) was investigated in 21 patients with type I diabetes mellitus in order to work out a method for glycemia correction. Preliminary results of the use of Biostator provided an opportunity for preparing an adequate scheme of insulin administration using microdosing apparatuses. The method made it possible to reduce the time for achieving compensation of the disease and attaining partial remission in patients with newly diagnosed type I diabetes mellitus.

Adolescent↗