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Biomedical subjects

E G Preuss

Publications and source records attributed to E G Preuss.

9 recordsLinked to original sources

[Disorders of the arterial blood supply in the upper extremities].

Arteriopathies of the upper half of the body may lead to considerable functional disturbances of the arm and severe deficits on the part of the central nervous system. Due to good comparison they scarcely cause or do not cause any complaints in a no unconsiderable part. The clinical material consisting of 4,162 patients from five annual courses had in 9.2% occlusion and stenoses localized in the supraaortic and brachial region. The in most cases systemic angiopathy here explains the frequently combined appearance with arterial processes in the pelvic and the leg region. According to the height of the occlusion we clinically differ types of carotis, shoulder girdle, upper arm and peripheral-acral obliteration, which in each case show differences concerning frequency, age of manifestation, etiology, distribution of sex and clinical degree of severity. The angiological basic diagnostics is based on the inspection, palpation of the arteries, auscultation of the vessels, bilateral measuring of the blood pressure after Riva-Rocci and functional examinations, such as fist closure test and Allen test, as well as clinical proofs or exclusions of neurovascular syndromes of the shoulder girdle. The special apparative angiological methods comprise the oscillo-, rheo- and vein occlusion plethysmography, the Doppler ultrasound technique, estimations of the ophthalmic pressure, isotopic methods and angiographic exploration. --The individual angiological examination methods are of different importance according to the height localisation of the angioorganopathy. --The incomplete syndrome of the aortic arch is taken into consideration. In short the author adopts a definite attitude to the demands of therapy.

Adult

[Functional peripheral ischemia].

The terminal circulation which plays an important role in the thermoregulation particularly at the periphery of the extremities is not infrequently irritated by false multifactorial regulations. As their sequela an increased tonus of vasoconstrictors and pathological vasodilatation lead to idiopathic and symptomatic functional angiolopathies. Transitions into organic vascular processes are no rarity. From the extreme functional behaviour patterns complaints and symptoms of the individual angiolopathies may be derived. Clinic, differential diagnostics and therapeutic possibilities of the angiopathic reaction position, of the acrocyanosis and its variants, of the intermittent functional acrosyndromes and of the erythromelalgia are treated from practical points of view. In contrast to the secondary functional angiolopathies, in which the basic disease is of decisive importance in questions concerning expertise, the idiopathic forms alone are scarcely of high significance concerning the restriction of the physical function.

Arterial Occlusive Diseases

[Doppler-sonographic findings in media sclerosis of the extremities, verified by radiography].

23 patients were examined who in the ultrasound-Doppler-pressure measurement were evident by too large peripheral systolic measuring values. On the X-ray pictures of the soft tissues of these patients more or less expressed linear and longitudinal calcifications of the vascular wall in the sense of a Mönckeberg sclerosis of the media were to be proved. Though these changes of the arteries which are to be established in most cases in diabetics of older age do not cause, as a rule, any disturbances of the peripheral blood supply, they are of clinical interest, since they falsify the results of indirect measurements of the pressure (pseudohypertension). An arterial obstructive disease which is simultaneously present may possibly been overseen and the false diagnosis of a therapy-resistant arterial hypertension may be made.

Adult

[Hemodynamics and metabolic parameters during use of the antihypertensive agent diazoxide].

The antihypertensive remedy diazoxide (hyperstat) was applied in 11 patients with hypertension of the clinical stages III and IV. The patients were applied a single intravenous injection of 20 ml = 300 mg diazoxide. The behaviour of blood pressure, pulse, blood sugar and cortisol level as well as of the blood supply in rest of the musculature of the extremities was tested and evaluated. Within 1 minute after the injection the systolic blood pressure decreased by 12%, the diastolic by 20%. After an above all show increase of the diastolic blood pressure once more a slight decrease of the systolic blood pressure followed after 90 minutes, which lasted several hours. Also after 24 hours the blood pressure did not reach the original value. The increase of the pulse rate was clinically not relevant. The blood glucose increased in the 5th minute, after 15 minutes it reached its culmination point and, beginning with the 30th minute it showed a decreasing tendency. The initial values were got after 180 minutes. After the 15th minute began a relative short-term decrease of the plasma cortisol, which, however, again increased after 60 minutes. On the other hand the occlusion-plethysmographic investigations of the veins showed an increasing blood flow in rest up to 3 hours after the injection.

Adult

[The spontaneous rhythm of the peripheral blood supply in diabetics needing insulin].

In order to study the spontaneous rhythmics of the peripheral blood supply under diabetic metabolic onditions with the help of venous occlusion plethysmography quantitative measurings were carried out in 20 long-term diabetics treated with insulin and in an adequate control group with healthy metabolism. The results were significant differences of the sizes of blood flow in rest as well as in the behaviour of the amplitudes and in the course of time of the spontaneous rhythmical varieties of the blood supply. Influences of age and duration of diabetes could not be proved on the basis of the number of patients. As to their evidence the findings are discussed with regard to the pathogenesis and early recognition of the diabetic neuro- and angiopathy.

Adult

[Investigation by borrowing-lending-phenomenon under conditions of intraarterial induced vasodilatation (author's transl)].

In fourty patients with peripheric atherosclerosis obliterans blood flow was measured by means of venous occlusion plethysmography during an intraarterial and an intravenous infusion of ATP. The intraarterial application showed a significantly higher increase of blood flow than the intravenous in the sick extremities. The "borrowing-lending-phenomenon" happened more seldom than after an intravenous load. This withdrawal of blood occurred most frequently in patients with proximal occlusions, when the infusion reached casually the arteria femoralis profunda only. The "borrowing-lending-phenomenon" can be measured by the poststenotic pressure and by the volume of blood flow in time. Then the patients complain about a begining or an increasing of an ischemic pain at rest.

Adenosine Triphosphate

[Angiological criteria of the functional capacity in arterial occlusive diseases of extremities after vascular surgery].

In order to avoid wrong estimations of the functional capacity of extremities with successfully reconstructed vessels in angioorganopathies, the use of reliable angiological measuring sizes in a broad spectrum is needed. Oscillography and longitudinal rheography as well as determinations of the arterial blood pressure deliver such qualitatively reliable parameters. For the judgment of the postreconstructive functional capacity one must not renounce the occlusion plethysmography of the veins which delivers quantitative measuring sizes. Other disturbances of the organs by the vascular basic disease present and concomitant diseases of middle and older age independent on the basic disease must always be taken into consideration in the general judgment.

Arterial Occlusive Diseases

[Diagnostic possibilities in aortic arch syndrome in ambulant care].

The diagnostic possibilities in the syndrome of the aortic arch in the surgery of the outpatient department are described. The importance of the leading symptoms in the anamnesis, the pulse palpation and auscultation, the inspection and the bilateral measurement of the blood pressure is elaborated. It is referred to the value of the simple functional test. Apparative investigation methods which are also used in the outpatient department are mentioned. The exhaustion of all possibilities which are at disposal for diagnosing already the early stages of the syndrome of the aortic arch is regarded as prognostically important in order to prevent irreversible cerebral lesions by a timely induction of necessary therapeutic measures.

Ambulatory Care

[Differential diagnosis of the aortic arch syndrome].

With the aid of the complexes of principle signs of the pulseless disease, the cerebrovascular insufficiency and the ischaemic-brachialgiformous symptomatology the different basic diseases, which are to be taken into consideration differential-diagnostically in a large number can clearly be recognized. With the cerebrovascular insufficiency compete intracranial organic processes and reductions of the volume of the cardiac output. In the brachialgiformous ischaemic syndrome further angiopathies, neurovascular syndromes of the shoulder girdle, nervously caused pain in the arm and a series of other very different starting-points must finally be taken into consideration. By means of a good interdisciplinary cooperation a clarification can be achieved also in difficult situations.

Aortic Arch Syndromes