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Biomedical subjects

E G Kuz'mina

Publications and source records attributed to E G Kuz'mina.

At least 19 recordsLinked to original sources
PubMed1990

[Immunologic indices of the blood and interstitial fluid in the evaluation of the treatment of secondary edemas of the upper extremities].

The efficacy of therapy of upper limb secondary edemas after 4 programs was compared among 83 patients. The methods were as follows: traditional method (TM) including routine conservative therapy, acupuncture (AP), He-Ne laser OK-13 and semiconductor laser against a background of traditional therapy. A study was made of the time course of the extent of edema, total protein, IG, G, A and M and circulating immune complexes (CIC) during therapy of such patients. Blood serum and interstitial fluid indices were compared. TM and AP were accountable for 20-21% fluid discharge, LT--for 38-44%. Besides, semiconductor laser therapy increased IG discharge up to 44-55% of the initial amount.

Acupuncture Therapy↗
PubMed1989

[Comparative analysis of various indicators of venous blood and peripheral lymph in healthy subjects].

Over four hundred industrial workers underwent immunological examination for quantitative and functional evaluation of the main blood lymphocyte and neutrophil subpopulations and reactions of sensitization to industrial allergens at the cellular and subcellular levels. Concurrent quantitative and functional T- and B-lymphocyte deficiency was revealed in 17.5 per cent workers; the majority of subjects were found to have changes in specific indices (30 per cent) or heterogeneous changes (11.5 per cent). The incidence and magnitude of the secondary immunodeficiency signs are shown to be dependent on the main unfavourable factors of the industrial environment which are also related to the sensitization to the industrial allergens, developing primarily in T- and B-lymphocyte deficient subjects (40 per cent of the 69 per cent sensitized). A principle of group formation is proposed for the dynamic follow-up of the outcome of the revealed signs of secondary immunodeficiency and their effect on the workers' health. A methodology is established for revealing secondary immunodeficiency state and sensitization during mass immunological examinations of industrial workers.

Adult↗
PubMed1987

[Effectiveness of various therapeutic schemes for patients with radiation edema of the extremities].

The efficacy of various therapeutic schemes: medicinal (basic therapy--BT), acupuncture (AP) and laser therapy (LT) against a background of basic therapy--was assessed and compared in 36 patients with radiation limb edema. It was established that a degree of a decrease in edemas, the improvement of indices of rheovasography grew in the following order: BT----AP----LT. The recovery of the lymph flow and immunological indices were the same in all therapeutic schemes.

Acupuncture Therapy↗
PubMed1987

[The bone marrow in Hodgkin's disease following radiotherapy and splenectomy].

A study was made of the bone marrow status in unirradiated zones of 33 patients with stage I-II Hodgkin's disease in complete 9-12 year remission after therapeutic irradiation of the lymphatic collectors of the upper part of the trunk in combination with irradiation of the spleen (16 patients) or splenectomy (17 patients). The total count of myelokaryocytes, myelogram, a relative and absolute content of lymphoid cells, immature granulocytes and elements of the erythroid series were defined in the punctates of the upper portion of the ilium. T- and B-lymphocyte count, the number of granulocytomacrophage (CFU-C) and stromal (CFU-F) precursor cells were defined using morphocytochemical and immunological methods. At that time an increase in the relative and absolute content of C- and B-lymphocytes was noted. The T-cell count and the total number of myelokaryocytes, on the one hand, and the content of immature granulocytes and erythronormoblasts, on the other hand, showed correlation of various degree which was particularly noticeable in the group of unoperated patients. The total number of myelokaryocytes in 1 microliter of the bone marrow of the patients after splenectomy, on an average, significantly exceeded that in the group of patients with the irradiated spleen. These changes were considered to be a result of the rearrangement of T-differentiating lymphocytes with their raised accumulation in the bone marrow after irradiation of a considerable volume of the lymphoid tissue and spleen or after splenectomy.

Bone Marrow↗
PubMed1987

[Restoration of immunologic indices following reflexotherapy in the combination treatment of radiation-induced edema of the upper limbs].

A study was made of the effect of combined treatment (routine drug therapy, massage, application of DMSO) alone and in combination with acupuncture and laser puncture on a degree of secondary (radiation) edema and immunological indices in 36 patients treated for breast cancer 2-15 years ago. These methods were shown to decrease effectively a degree of edema by 22-37%. The highest effect was achieved using laser puncture against a background of the main treatment. All types of combined modality treatment promoted the return of the patients' immunological status to normal (an increase in low and a decrease in high values). The most effective recovery was noted in the lymphocyte count, the ratio of helpers (inductors and suppressors) killers, and lymphocyte blast transformation reaction to mitogens.

Acupuncture Therapy↗
PubMed1986

[Role of splenectomy in impairing lymphocyte elimination in patients with lymphogranulomatosis].

The study group included 113 patients in a continuing 1 to 10 year-long complete clinical-hematological remission from Hodgkin's disease. 43 of them had prior splenectomy. The latter revealed a higher level of lymphocytes (chiefly 0-cells) and a diminished response of mononuclear blood cells to PHA as compared to the other patients and healthy controls. Also, they had more lymphocytes which became capable of E-rosette formation following a short-term incubation at 37 degrees C (lymphocyte reactivation by means of surface modification). The negative correlation between the reactivated T-cells level and mononuclear cell response to PHA suggested a functional blocking of T-cells involving damage to membranes. The absence of reactivated T-lymphocytes in nonsplenectomized patients was regarded as circumstantial evidence for the role played by the spleen in withdrawing faulty lymphocytes from peripheral blood.

Hodgkin Disease↗