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Biomedical subjects

E G Brownstein

Publications and source records attributed to E G Brownstein.

6 recordsLinked to original sources

Torture.

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Humans

Blunt abdominal trauma simulating Crohn's disease of the terminal ileum.

A case of acute small bowel obstruction is presented occurring five months after blunt abdominal trauma due to a seat-belt injury. The problem of early diagnosis is discussed. With the increasing use of seat-belts, clinicians should be aware of this condition as part of the 'Seat-Belt Syndrome'. Histopathology of the affected segment of ileum was found to closely resemble Crohn's Disease.

Abdominal Injuries

Multiple metachronous gastro-intestinal carcinoma.

A patient who developed multiple metachronous gastro-intestinal carcinoma is described. This patient has had multiple invasive carcinoma of the colon, jejunum and stomach over a 34 year period, commencing at the age of 44 years. All the colonic tumours have been Duke's A Grade, although penetration has occurred to the serosal level. The family pedigree of the propositus shows an autosomal Mendelian dominant gene pattern with a characteristic early age of onset and a significant frequency of multiple metachronous primary malignant neoplasms. Identification of this syndrome provides an opportunity to include in a surveillance program, those unaffected patients in the pedigree who have an extra risk of early development of cancer at specific sites.

Adenocarcinoma