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Biomedical subjects

E G Anderson

Publications and source records attributed to E G Anderson.

At least 55 records · Page 3Linked to original sources
PubMed1993

Germ warfare.

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Anecdotes as Topic↗
PubMed1993

Snow jobs.

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Emergencies↗
PubMed1992

Serotonin preferentially hyperpolarizes capsaicin-sensitive C type sensory neurons by activating 5-HT1A receptors.

The effects of serotonin (5-HT) were investigated by intracellular recording from 179 dorsal root ganglion (DRG) cells classified by conduction velocity. Bath applied 5-HT depolarized 82% and hyperpolarized 4% of the A-type cells. In C-type cells, 5-HT depolarized only 41%, but hyperpolarized 39% of the cells. The depolarizing responses were of two types; an increase or decrease in R(in), mediated by 5-HT2or3 receptors, respectively. These receptors were observed in both A- and C-type cells. Hyperpolarizing responses were largely confined to A(delta)- and C-type cells. Carboxamidotryptamine and 8-OH-dipropylamino-tetralin were full agonists in eliciting hyperpolarization, and metitepin, spiperone and spiroxitrine behaved as competitive antagonists. This indicated that hyperpolarization was mediated by a 5-HT1A receptor. A 5-HT1A&3 receptor were found co-localized on some C-type cells. A strong depolarizing response to capsaicin was observed in the subgroup of C-type neurons that were also hyperpolarized by 5-HT. Thus a co-localization of capsaicin and 5-HT1A receptors was also observed.

Animals↗
PubMed1991

Traumatic epidermal inclusion cysts due to shoe impingement: a report of two cases.

Two cases are presented of bilateral traumatic inclusion cysts occurring on the dorsum of the first metatarsophalangeal joint. Both cases were women who wore high-heeled fashion shoes and the cysts occurred where the edge of the shoe impinged on a particularly prominent extensor hallucis longus tendon. Inclusion cysts have not previously been reported on the dorsum of the foot and their occurrence where impingement exists confirms a traumatic etiology. The importance of identifying the causative factor in such cases is emphasized.

Adult↗