[Conservative treatment of achalasia with an electronic-mechanical dilator].
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Biomedical subjects
Publications and source records attributed to E Frimberger.
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A study was designed in order to determine whether waterfilled intragastric balloons are superior to airfilled balloons for facilitating weight reduction. In the first volunteer the small intestine was obstructed by the dislocated waterfilled balloon. This complication was successfully treated by transabdominal fine needle puncture of the balloon. In contrast to airfilled balloons waterfilled balloons offer two advantages: water does not escape through the very thin wall of the balloon; the intraabdominal location of a waterfilled balloon is easily checked by sonography.
The conservative treatment of achalasia of the esophagus with balloon or mechanical dilators may be difficult, or even impossible, it the esophagus in an advanced illness is so tortuous (sigmoid esophagus) that the dilator cannot be placed in the cardia. An endoscope dilator with the aid of which dilation is readily possible even in such cases, has been developed by various individuals. Our own experience and the results obtained in 11 patients with esophageal achalasia treated with the endoscope dilator, are presented. The particular advantages of this method of treatment are simple, low-risk placement of the balloon in the cardia before and during dilation, and the possibility of inspecting the cardia for complications immediately after dilation.
In a double-blind study comprising 33 patients (24 males and 9 females) the effects of sulfasalazine enema (3%) in acute left-sided ulcerative colitis was tested. The success rate of 73.6% is comparable with the results achieved with the oral treatment. The rate of side effects however was markedly reduced (no side effects occurred in our patients). Compared to the SASP-therapy with suppositories, the enema had the advantage of being applicable to more proximal parts of the colon.
In cases of achalasia of the oesophagus where a metal or balloon dilator cannot be placed into the functional stenosis dilatation--which otherwise is the treatment of choice--is not possible and the patient must be operated on. With a new instrument, an endoscope with built-in dilator, dilatation is also possible in these cases. Operation can thus be avoided as is demonstrated by treatment of a 60-year-old female patient with extensive curvature of the oesophagus in the prestenotic area.
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Among 1258 polyps from the lower gastro-intestinal tract removed by rectoscopy or coloscopy and examined histologically there were 744 adenomas, 72% tubular, 27% papillary and 1% villous. 96.5% of all adenomas were extracted from patients aged over 40 years. Four fifths of the tumours were found in the rectum and sigmoid colon. Only 6% of the tubular adenomas were more than 15 mm in diameter, compared with 32% of papillary and 57% of villous adenomas. The special significance of the adenomas lies in their potential malignancy (adenoma-to-cancer sequence).
Polyps are often associated with carcinoma in the colon. The incidence of colorectal polyps with single carcinoma is up to 25% and with multiple carcinoma up to 75%. Not infrequently both synchronous and metachronous carcinoma are found in the colon and rectum. These findings emanate from a sample of 367 patients (in this hospital) with colorectal carcinoma during the period 1973 to 1977. The incidence of synchronous and metachronous carcinoma as well as severe dysplasia (focal carcinoma) in adenomatous polyps was nearly 8%. In slightly more than 50% of cases involving a single carcinoma, there was no evidence of an accompanying condition or later development. In more than 20% of the cases single carcinoma was accompanied by synchronous and metachronous polyps. These figures eloquently illustrate the necessity for closely coordinated postoperative care of patients with colorectal carcinoma.
Among 1258 polyps from the lower gastro-intestinal tract removed by rectoscopy or coloscopy and examined histologically there were 744 adenomas, 72% tubular, 27% papillary and 1% villous. 96.5% of all adenomas were extracted from patients aged over 40 years. Four fifths of the tumours were found in the rectum and sigmoid colon. Only 6% of the tubular adenomas were more than 15 mm in diameter, compared with 32% of papillary and 57% of villous adenomas. The special significance of the adenomas lies in their potential malignancy (adenoma-to-cancer sequence).
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A technique is described by which the secretory capacity of the stomach can be determined. It appears to be superior both to intragastric titration along with intragastric pH-metry and to common analysis of gastric juice obtained by aspiration. There is no essential difference when comparing results obtained intraindividually by intragastric titration with the pH being measured either inside or outside the stomach. When titrating intragastricly with the pH being measured extragastricly, a tube is used which can be check more easily, remains usable much longer, and - as a result of its smaller diameter - is tolerated much better by the patient. In contrast to common analysis of gastric juice obtained by aspiration, by intragastric titration with the pH being measured extragastricly gastric acid can be determined at its site of production (less volume loss and rediffusion of H+ -ions into tissue), the results obtained representing more accurately the true secretory capacity of the stomach. As can be seen from its results, the technique presented here is apt particularly to both testing antacids and the substances interfering with gastric secretion; it also appears to be superior to common analysis of gastric juice obtained by aspiration.
Treatment by coloscopy is almost exclusively identical to endoscopic polypectomy. From a technical standpoint, coloscopic polypectomy can be regarded as a sophisticated method: risks are minimal. Of a total of 1236 polyps resected endoscopically over a period of 4 years, two-thirds were resected with a coloscope. Almost 70% of the polyps were adenomas; 10 polyps proved to be carcinomas (without parts of an adenoma); 64 out of 797 polypous adenomas were associated with focal carcinomas. Indications for coloscopic polypectomy are all stalked polyps and those broad-based sessile polyps up to a diameter of about 3 cm.
A new chair support for flexible endoscopes simplifies sigmoidoscopic endoscopy. The endoscopist sits on a stool with a moveable support for the endoscope. This allows working without much fatigue and the endoscopist can insert and move the endoscope himself. We examined 50 patients in the described technique. We reached an average depth of intubation of 45-50 cm and the average examination took less than 5 minutes.
A yoghurt-spoon with a long handle which could not be removed initially from the stomach during several sessions was finally successfully extracted by a new simple device.
In contrast to the hitherto available polypectomy snares the newly designed snare for endoscopic polypectomy offers the following advantages: when the tip of the endoscope is directed towards the polyp the snare turns automatically into a position parallel to the polyp-bearing bowel wall. "Combusting ulcers" are avoided, a homogenous circular flow of electric current is guaranteed.
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