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Biomedical subjects

E Franco Miranda

Publications and source records attributed to E Franco Miranda.

At least 19 recordsLinked to original sources

[Intracavernosal methoxamine self-injection for the treatment of low-flow recurrent priapism].

We report the case of a young man with a recurrent idiopathic priapism, successfully treated with methoxamine intracarvenosal self-injections. The patient was instructed in intracorporeal self-injection of this pure alpha-1 adrenergic agonist, which provided complete detumescence. The patient became asymptomatic after one month of domiciliary treatment. We conclude that intracavernosal self-administered methoxamine can be a useful treatment of recurrent idiopathic priapism.

Adrenergic alpha-Agonists↗

[Renal pseudotumor secondary to acute pancreatitis. Report of one case].

We present the case of a renal pseudotumor corresponding to a esteatonecrotic granuloma, secondary to an enolic acute pancreatitis a few months ago. The main caractheristics, diagnosis and terapeuthics of the renal pseudotumors are discussed with the case report of a 60 year old man who presents a renal mass founded incidentally at a control computed tomography.

Granuloma, Plasma Cell↗

[Our experience with the implant of single component integrated prostheses (Hydroflex-Dynaflex)].

INTRODUCTION AND OBJECTIVES: To present our experience with Hydroflex and Dynaflex self-contained inflatable penile prosthesis. MATERIAL AND METHODS: Between october 1988 and december 2000 a total of 63 men underwent implantation of 8 Hydroflex and 55 Dynaflex penile prosthesis. The follow-up period ranged from 12 and 127 months (mean 54.5). RESULTS: A total of 124 cylinders were implanted (in 2 cases only 1 cylinder was implanted). During implantation 3 corpora cavernosun ruptures were present, but implantation was possible in 2. Specific complication rates after implantation were as follow: early infection, 3 patients (4.7%); late infection, 1 patient (1.6%); pain that needed readmission 2 cases (3.2%); mechanical device failure, 7 cylinders in 6 men (mean time 83.5 months). 7 men (11.1%) needed prolonged teaching time to operate the prosthesis. Only 6 men (9.5%) wer dissatisfied with the prosthesis. It was possible to change only 1 cylinder when needed. CONCLUSIONS: Self-contained inflatable prosthesis brings good results on long time use. The mechanical malfunction rate is low and it is possible to change only one cylinder if needed. An important number of patients need intensive and prolonged teaching time to obtain a successful result.

Adult↗

[Vasculo-renal disease].

UNLABELLED: The kidney as an apo-exocrine organ has two important functions: the control of homeostasis and arterial blood pressure. Any pathological disorders witch alters the renal blood flow results in two consequences: renovascular hypertension and renal insufficiency. Renal revascularization looks for with priority the improvement of renal function; the good response and control of hypertension shall come after. The goals of this paper is to actualize the sophisticated diagnostic methods (Angiography, Eco-Doppler, AngioCT, AngioMR, Angioscopy; and the use of contrast potential-mediums), functionality tests (RN and MR with Captopril) and management (Percutaneous transluminal angioplasty, simple or covered Stents, Embolizations, Occlusive balloons, Fibrinolysis and Trombus Aspiration; direct Arterial Surgery and renal Autotransplantation) of different renovascular diseases. (Blunt renal injuries, Stenosis, Aneurysms. A-V fistuls, Acute Occlusions or arterial and venous, Thrombosis. Nutcraker Syndrome). The possibility of the presence of an inverse venous Fraley's Syndrome is presented and discussed. CONCLUSIONS: A controversy of the last technical methods are established and discussed and a Guideline is recommended for each renal vascular disease.

Humans↗

[Incidence and treatment of urinary lithiasis in renal transplantation].

INTRODUCTION: Urinary calculi is an uncommon complication in kidney transplantation; several stone risk factors are found in transplanted patients, but in most cases there is not a relationship between these risk factors and stone formation. The treatment of these patients is complex due to their both immunosuppressive status and border-line renal function. MATERIAL AND METHOD: From 1980 to February 2000, 1198 kidney transplant have been performed in our institution. We describe our series consisting in 22 urinary calculi (15 in the graft, 3 in the urether and 4 in the bladder) in 18 patients, including 7 stones detected in cadaveric donor patients. RESULTS: We performed external shock wave lithotripsy in 7 patients, bench surgery in 4, endoscopic mechanic lithotripsy in 5, open surgery in 1 and observation in 6. Calcium oxalate (mono and dihidrate) was found in 9 of 13 calculi. Metabolic changes were found in 15 of the 18 patients, the most common was hiperuricemia. There were not complications of every treatment applied and 9% of them needed a savage treatment. We found recurrence in 4 cases (22.2%). Now 12 of the patients are stone-free (66.7%) and three have non-significative stones (83.3% without symptoms). CONCLUSIONS: Detection of renal calculi in cadaveric renal donors is not a reason to refuse the graft for further transplantation. In both renal calculi up to 2 cm and uretheric calculi surgical treatment is assessed as first option. In caliceal stones smaller than 5 mm observations is the best treatment.

Humans↗

[Iliac pseudoaneurysm in non-functioning renal graft 10 years after embolization].

The arterial pseudoaneurysms are an infrequent complication or renal transplantation. Depending on her localization, are divided in intra and extrarenal. The first are relacionated with the practice of percutaneous needly biopsy. The seconds are associated with defects of vascular anastomose or infection onsurgical area (with relative precocious presentation). Presentation of case of a iliac pseudoaneurysm in non-functional kidney allograft embolizated ten years before. This pathology, for this clinic gravity, requires urgent surgical treatment.

Adult↗

[Pelvic lipomatosis: clinical review and report of 4 new cases].

First described by the end of the fifties, pelvic lipomatosis is an uncommon disease that develops as a result of an excessive proliferation of benign fat tissue within the perivesical and perirectal spaces. The compressive effect on the urinary, and to a lesser degree, the digestive and vascular structures result in the well-known symptoms. Diagnosis is reached through X-ray studies, primarily computerised tomography. Contribution of four new cases in young males diagnosed through imaging studies as well as biopsies in three of them. Evolution has been varying, with medical control of symptoms in two cases and renal function impairment due to upper obstructive uropathy in the other two.

Adult↗

[Suprarenal myelolipoma: an "incidental" disease].

With the development and improvement of imaging techniques, we are witnessing a greater number of disease diagnoses considered uncommon only a few years ago. When the diagnosis of a tumoral disease occurs "incidentally" while performing an imaging examination for other reasons, we name the condition "INCIDENTALOMA". A clear example of these in suprarenal conditions is the myelolipoma. Myelolipoma is a benign and non-functioning tumour originating in the suprarenal cortex and histologically consisting of mature fat and haemopoietic tissue. Given its benign and usually inactive nature, the current approach is a conservative attitude. Surgical exeresis is only accepted when large tumoral masses are present or in complicated cases. This paper presents a new case of a 10 cm suprarenal myelolipoma incidentally diagnosed during routine ultrasound examination in a 47-year old male patient. Subsequent exeresis of the suprarenal mass and pathohistological study confirmed the diagnosis.

Adult↗

[A retrovesical mass (intestinal duplication].

The etiology of retroperitoneal masses that can compress the bladder or the ureters and can result in urinary sings and symptoms is highly varied and may include both benign and malignant entities. This paper contributes one patient that presented with relapsing retrovesical mass with cystic features. The diagnosis from the pathoanatomical study was intestinal duplication.

Adult↗

[Diverticulum of the female urethra: presentation of 3 cases].

Contribution of three cases of female urethral diverticulum diagnosed and treated in our Service. Presence in women presenting to the practice with chronic signs and symptoms of the lower urinary tract unresponsive to conventional medical management should be ruled out. A review is made of the most significant aspects in terms of clinical presentation, diagnosis and therapeutic options.

Adult↗

[Mesoblastic nephroma in the adult. Report of a case].

Congenital mesoblastic nephroma is a benign renal tumour of uncertain histogenesis and characteristic histology that can be mistaken with Wilms' tumour and other mesenchymal neoplasias. It is nearly always diagnosed in the early months of life, and its presentation in adults and older children is very rare. Its benign behaviour justifies the diagnostic significance mainly to avoid over-treatment. This paper presents one case of mesoblastic nephroma in a 17-year old female which appeared as a large abdominal mass. The therapeutic approach was radical nephrectomy and, after a 2-year follow-up, the patient has been found to be disease free.

Adolescent↗

[Kidney transplantation with donors in heart block. Long-term results].

OBJECTIVES: The shortage of renal grafts has led to the search for other alternatives. The use of grafts from non-heart-beating donors (NHBD) can increase the number of transplants 8% to 20%. Clinical studies conducted by different groups, have found that the long-term graft and patient survival are not different from those of recipients of kidneys from heart-beating donors (HBCD). METHODS/RESULTS: The long-term results of a group of 52 recipients of NHBD kidneys were compared with those of 98 recipients of HBCD grafts. There were no differences in donor and recipient ages, HLA compatibility, reperfusion and cold ischemia times. There were no differences in the incidence of rejection episodes or non-functioning kidneys. Warm ischemia between 30 to 60 min or < 30 min did not influence the incidence of non-functioning kidneys. However, NHBD graft recipients had a higher incidence of acute tubular necrosis (67% versus 46%), recovers of renal function was slower, the duration of oliguria was longer and dialysis was required. The 8-year actuarial survival data were similar for both groups; 65% for the NHBD and 70% for the HBCD graft recipients. CONCLUSIONS: We can conclude that NHBDs are an important source of donor kidneys. The 12 points established by The First International Workshop on Non-Heart-Beating Donors which appear at the end of the present article are embodied in the Treaty of Maastricht regulations of organ transplantation from non-heart-beating donors.

Actuarial Analysis↗

[Renal angioscopy].

Presentation as a novelty of the application of endoscopic methods in the display of the renal artery (angioscopy). Review of findings seen in the renal artery of a donor corpse with polytraumatism using direct view with a MiniScope-type rigid urethroscopy and the possible future application of this technique.

Angioscopy↗

[Transplantectomy today: indications and complications].

Analysis of the indications for transplantectomy and its complications over a 12-year period. Over a total of 159 failure grafts, we performed 53 transplantectomies (33.3%). The percentage of complications was 16.9%. Three patients died (5.6%) during the more or less immediate post-operative period. In our experience, consistent and prolonged maintenance of immunosuppression should avoid the need for transplantectomy in a high percentage of grafts. Only 15 transplantectomies were made on 104 failure grafts after 6 months (14.4%). Our short but successful experience with embolization of 2 rejected grafts confirms the validity of this conservative alternative versus conventional surgical transplantectomy in selected cases.

Humans↗

[Arteriovenous fistulae following percutaneous renal biopsy in renal transplantation. Selective arterial embolization].

Five cases of clinically severe arteriovenous fistulae (AVF) secondary to percutaneous renal biopsy in patients carrying a functional renal graft were diagnosed and treated in our centre. Occlusion via superselective intraarterial embolization accomplished successful control in every case. We insist on the therapeutical value of this minimally invasive technique, which furnish it with a particularly relevant role in renal transplantation.

Adult↗