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Biomedical subjects

E F Ring

Publications and source records attributed to E F Ring.

At least 55 records · Page 3Linked to original sources

Thermography and rheumatic diseases.

The common factor in most of the rheumatic diseases is an arthritis. Radiometry and thermography have been shown to indicate and measure heat resulting from localised inflammation. In rheumatoid arthritis, juvenile arthritis, osteoarthrosis, gout and ankylosing spondylitis abnormal heat distribution has been recorded over affected joints. Experimental evidence has shown that temperature change reflects the inflammatory state of the joint, and that this may be used to measure the effect of therapy by oral, systemic and local drug therapy, and also surgery, i.e. synovectomy.

Adrenocorticotropic Hormone↗

Measurement of inflammation in man and animals by radiometry.

1. A radiometer is described, which is sensitive to infrared radiation in the range 0-25 mum, and which, after calibration with a black body standard can be used as a non-contact, fast reading thermometer.2. An example of acute joint inflammation in a patient with rheumatoid arthritis is described. The temperatures over the joint measured by radiometry, followed inflammatory changes in the joint effusion.3. Using rats, the method of measuring inflammation by radiometry was compared with measurements of increase in joint size. Changes measured by radiometry preceded changes shown by increase in joint size.4. The radiometer method was able to demonstrate the effect of an anti-inflammatory drug, given orally, against carrageenin inflammation.5. The procedure was found to be an accurate means of measuring inflammation and the anti-inflammatory effects of drugs. It was faster and less tedious than the other methods for the quantitative measurement of inflammation in man and animals.

Animals↗

Infra red microscopy.

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Bacteriological Techniques↗

Secretion and localization of cathepsin D in synovial tissues removed from rheumatoid and traumatized joints. An immunohistochemical study.

The proteinase cathepsin D which degrades proteoglycan was never demonstrated in extracellular sites in tissues from patients with traumatized meniscoid cartilage, either before or after culture with an antiserum to human cathepsin D. In contrast, in synovia (but not usually cartilage) from the knees of 6 of 11 rheumatoid patients, extracellular cathepsin D was commonly detected by culturing tissues with an antiserum to this enzyme.

Animals↗

Heart rate evaluation of axillary and elbow crutches.

The aim of this study was to compare the possible effect on heart rate in patients with a walking disability using 11 different crutch designs. Eighteen patients, over the age of 18 years, who had used crutches for a minimum of 2 weeks before the study were divided into two groups: elbow and axillary crutch users respectively. The former tested six different designs of elbow crutches and the latter five different pairs of axillary crutches. Heart rate was recorded, using a portable digital pulse monitor during a 5-min walk on the level at self-selected velocities. Walking heart rates increased between 28.6 and 58.8% compared with the resting phase. No differences were found in either heart rate or walking speed between elbow crutches. However, a significant difference (p less than 0.001) in heart rate was noted between elbow crutch users who were non-weight bearing on their injured leg compared with those who were partial-weight bearing. The Canadian axillary crutch showed the lowest increase in heart rate at comparable walking speeds compared with other axillary crutches. Prescribers should be aware that the reduced energy requirements of the Canadian crutch would benefit patients with reduced cardiorespiratory function.

Adult↗