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Biomedical subjects

E Epstein

Publications and source records attributed to E Epstein.

At least 19 recordsLinked to original sources
PubMed1991

Strategies for using patient instruction sheets.

Patient instruction sheets are a patient pleasing practice tool, especially if used creatively before seeing patients, to augment telephone conversations, and to detail postoperative care. Customizing, availability, and other strategies for optimal use of patient instruction sheets are discussed. Although patient instruction sheets are significant time savers, their updating, customizing, and effective use requires a small investment of physician time and effort.

Forms and Records Control↗
PubMed1991

Accidental intravascular injection during infiltration anesthesia of the skin.

Accidental intravascular injection of lidocaine during the induction of infiltration anesthesia for dermatologic surgery is an occasional and harmless occurrence. The author noted nine such episodes in a three-year period of full-time private dermatologic practice. A very brief, sharp, stinging pain lasting only seconds and immediately followed by blanching in a vascular distribution characterized these episodes. The blanching, resulting from the 1:200,000 epinephrine solution used in the lidocaine solution usually disappeared within five to ten minutes. Patients experienced no ill effects. The standard textbooks and reviews caution practitioners to aspirate before injecting a local anesthetic; this is unnecessary when performing infiltration anesthesia of the skin.

Anesthesia, Local↗
PubMed1990

Selective accumulation of lymphocyte precursor cells mediated by stromal cells of hemopoietic origin.

Thymocytes were propagated in long-term cultures supported by stromal cells of both bone marrow and thymus origin. Interleukin 2 (IL-2) supplementation augmented the cell yield and allowed detailed phenotype analysis. Within 2-3 months of culture a cell population was selected in which the expression of Thy-1 antigen persisted, CD4 and CD8 antigens gradually declined, and Pgp-1 antigen, found on less than 5% of fresh thymocytes, was strongly increased. This cultured cell population (Thy-1.2 origin) contained no detectable spleen colony-forming units (CFU-S) but efficiently repopulated the thymus of Thy-1.1-irradiated congenic mice, indicating the precursor T-cell nature of the population. Upon removal from the stroma, the T cells exhibited poor cytotoxicity towards syngeneic tumor cells. Further propagation with IL-2 in the absence of stroma resulted in the acquisition of cytotoxic ability. Replacement of the horse serum used in the above experiments with fetal calf serum resulted in accumulation of cells expressing B220 antigen. This experimental model provides the means to maintain lymphocyte precursor cells in long-term culture and to further study their differentiation in the absence of stroma, both in vitro and in vivo.

Animals↗
PubMed1990

Laboratory measurement of bilirubin.

Several methods for determination of total bilirubin and its fractions have been critically discussed. Methods for serum determinations are summarized in Table 1. Because results of direct bilirubin cannot necessarily be equated with conjugated bilirubin, care must be taken in interpreting results from different laboratories, and clinicians are encouraged to become familiar with methods in use at their own institutions. Despite problems reported in the literature, bilirubin determinations, together with a reference range established for one's own patient population, should provide valuable information for patient management.

Amniotic Fluid↗
PubMed1979

Electro-excision of melanomas.

Excision of primary malignant melanomas by a cautery (actual heat) or by endothermy (electric cutting current) is a simple method of management. It consists of excision of a disc of tissue that contains the evident malignancy plus some surrounding normal-appearing skin.

Electrosurgery↗
PubMed1979

Prognosis of primary malignant melanomas.

In all probability, a patient with a primary malignant melanoma, but without clinical, radiological or other laboratory evidence of metastases, has a 75 to 80% chance of living five years and 55 to 65% of surviving for ten years regardless of other prognostic factors and the skill with which surgical therapy is applied. It has not been established whether or not malignant melanomas are absolutely curable.

Humans↗
PubMed1979

The buried horizontal mattress suture.

The buried horizontal mattress suture (BHMS) is a new tension suture technique using synthetic absorbable polyglactin 910 suture. When used in minor surgery of the trunk and extremities, this technique eliminates significant suture marking.

Dermatologic Surgical Procedures↗
PubMed1979

A simple technique for managing digital mucous cysts.

Digital mucous cysts can be effectively managed by multiple needlings and expression of contents. This simple technique cures about two thirds of the lesions. Most of those remaining are reduced to small asymptomatic nodules.

Adult↗