Biomedical subjects

E E Prescher

Publications and source records attributed to E E Prescher.

3 recordsLinked to original sources

PubMed1983

Influence of several plant and animal proteins on rat pancreas.

Twelve different plant and animal proteins were fed to rats for 4 weeks. Trypsin inhibitor (TI) content of the diet was significantly correlated with (although not directly related in all cases to) pancreas weights and with the pancreatic biochemical parameters that indicate hypertrophy. In vitro, but not in vivo, digestibility was correlated with the TI content of the diet. Quantity of DNA per gram pancreas was not found to be related to TI content. A second experiment compared graded levels of TI from raw or heated soy flour and soy protein isolate (SPI). The SPI diet produced higher relative pancreas weights per TIU than did the flour diets. Two commercial SPI's were fed as is or autoclaved in a third experiment. Autoclaving to very low TI values made no improvement in weight gain or pancreatic parameters measured, indicating that there may be a threshold level of TI below which rat pancreata do not respond, and that other factors in SPI are responsible for the slight pancreatic enlargement seen with SPI compared to casein.

Animals↗

PubMed1978

Effect of protein-bound lysinoalanine, N epsilon-DL-(2-amino-2-carboxyethyl)-L-lysine on fetal and neonatal rats.

Diets containing 5% to 30% of an alkali-treated isolated soybean protein (ATSP) containing 1% lysinoalanine (LAL) were fed to female Sprague-Dawley rats during gestation and lactation to provide 500, 1,000, 2,000, or 3,000 ppm LAL in the diet. An isolated soybean protein containing no LAL was used as control. No teratological effects were observed. No significant differences in birth weight, mortality, live births/litter, or number of pups/litter was found at any LAL level fed. However, significantly decreased weight gains were observed in pups from dams fed either 2,000 or 3,000 ppm LAL. No LAL was found in the milk, and protein content of all milks was similar. The decreased weight gains appeared to be due to reduced milk production in dams fed high levels of ATSP.

Alanine↗

PubMedDate not supplied

Apparent nitrogen digestibility data: AACC-ASTM collaborative study.

Apparent nitrogen digestibility data were obtained from 4 laboratories for 6 protein sources and 2 diet levels, 6 and 10% protein, after a 2-day adaptation period during the AACC-ASTM protein efficiency ratio (PER) and net protein ratio (NPR) collaborative studies. For 5 protein sources fed as 10% of the diet, the interlaboratory variation as measured by coefficient of variation (CV) values was low (1.5-3.5%), indicating high precision of the method. Wheat flour (6% protein diet) had the highest variation and, therefore, the lowest precision (CV of 7.10%). The interlaboratory variation (CV value) for 3 of the 4 laboratories was considerably lower, less than half that for the 4 laboratories. An analysis of variance of apparent nitrogen digestibility data indicated significant (P less than 0.05) effects for the 4-laboratory group due to laboratories and protein diets at both 10 and 6% protein levels, and for the 3-laboratory group at the 10% protein level. The 3-laboratory ANOVA for the 6% diets indicated a significant effect (P less than 0.05) due to diet only.

Animals↗