Photo essay: Takayasu's disease.
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Biomedical subjects
Publications and source records attributed to E E Boldrey.
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PURPOSE: To define the relationship between vitreous cells and retinal tears in eyes without recent flashes or floaters. METHODS: Five hundred eighty-five consecutive patients who complained of light flashes, floaters, or both in one eye had their asymptomatic or not recently symptomatic fellow eye examined prospectively for vitreous cells and retinal tears. RESULTS: Of these fellow eyes with 2+ or more vitreous cells (10 or more cells per 1-mm slit-lamp field), 31.6% (6/19) had one or more tears vs 1.6% (9/566) of those with 1+ or fewer cells (less than nine cells per 1-mm slit-lamp field) (P = .0001). CONCLUSIONS: A substantial number of vitreous cells, even in an eye with no recent symptoms, is correlated with the presence of a retinal tear. Additionally, a retinal tear may exist in an eye with 1+ or fewer cells.
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Untreated subfoveal choroidal neovascularization (SFCN) often progresses to destroy much central visual function. In this study, laser photocoagulation which included the entire foveal avascular zone was applied to SFCN in the second eye of 13 consecutive patients. Each patient had untreated SFCN in their first eye with visual acuity less than or equal to 20/400. Each second eye had SFCN of recent onset which was less than or equal to 1 disc diameter (DD) in size and visual acuity less than or equal to 20/200. In 10 of 13 (76.9%) treated eyes, SFCN was eliminated for 3 to 30 months. These eyes all retained strikingly better visual fields (Amsler or automated) than their fellow untreated eyes, markedly better subjective vision, and Snellen visual acuities of 20/70 to 20/400. Foveal photocoagulation may be useful in selected cases of SFCN with small neovascular nets and poor visual acuity.
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Two eyes were enucleated for angle-closure associated with familial exudative vitreoretinopathy. Characteristic features included total retinal detachment, peripheral retinal vascular proliferation, and a fibrovascular preretinal membrane. Angle-closure glaucoma developed in one case when sudden massive subretinal hemorrhage, associated with abnormal intraretinal vessels, produced anterior displacement of the lens-iris diaphragm; in the second case, angle-closure was associated with the development of rubeosis iridis. Intraretinal inflammatory cells and exudates were also seen in the enucleated eyes.
Retinal neovascularization, a rare complication of ocular toxoplasmosis, is a source of vitreous hemorrhage. We examined three patients (all women, 70, 36, and 19 years old) with inactive toxoplasmosis scars associated with occlusion of a retinal arteriole or venule passing through the scar, capillary nonperfusion, and adjacent retinal neovascularization. In two patients photocoagulation of the ischemic areas produced a cessation of hemorrhage and the disappearance of neovascularization. In the third case, the neovascular frond was avulsed from its supplying retinal arteriole without treatment.
Paramacular changes presumably induced by operating microscope light have been described previously in six patients who had undergone extracapsular cataract extraction with posterior chamber lens implantation. Twelve additional patients are reported, including pseudophakes and nonpseudophakes, macular and paramacular burns, and no visual loss and severe visual loss. Burns occurred in spite of filters and light barriers used in some cases. Light sources were tungsten bulb or halogen/fiberoptic. Three cases had essentially normal preoperative angiography. Currently recommended safety measures have not eliminated this complication.
A total of 589 patients (369 women and 220 men, 123 of whom were less than 40 years old and 52 of whom were more than 70 years old) with photopsia, vitreous floaters, or both participated in a prospective study designed to identify patients at particularly high risk for retinal tears. The patients were graded on a number of factors before undergoing peripheral retinal examinations. Computer analysis showed that the following factors had the strongest associations (P less than .001) with retinal tears: visual symptoms of diffuse dots (62 of 120 patients, or 51.7%), many vitreous cells (graded 2+ or worse) (61 of 94 patients, or 64.9%), and grossly visible vitreous or preretinal blood (51 of 56 patients, or 91.1%). Of the 176 eyes that had at least one of these three conditions, 93 (52.8%) had retinal tears compared to 16 of the remaining 413 eyes (3.9%). Although other factors correlated with retinal tears to some degree, the associations were not strong enough to help select the high-risk group.
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Ocular industrial lasers burns in seven patients were analyzed as to cause, severity, and type of injury. Ocular damage ranged from minimal retinal burns to extensive areas of damage with commotio retinae and vitreous hemorrhage. Visual loss ranged from complete recovery without residual defect to a profound decrease in central acuity. The kinds of lasers causing these injuries were neodymium YAG, argon, krypton, and rhodamine dye. Severity of injury was related to several factors. Some degree of carelessness was involved in all injuries.
A case of successfully treated Aspergillus endophthalmitis is presented. Treatment consisted of wide vitrectomy. At the end of surgery, 5 micrograms of amphoteracin B were injected into the center of the vitreous cavity, and an additional .75 mg was given subconjunctivally both at surgery and on the second postoperative day, at which time 2 mg of dexamethasone were also given subjunctivally. Systemic antifungal agents were not used. After 2 1/2 months, the second eye developed a similar metastatic infection from heart value vegetation. This case illustrates that use of wide vitrectomy and intravitreous antifungal agents alone can cure Aspergillus endophthalmitis and preserve useful vision.
Seventy-eight 5 mm silicone sponges were sutured to autopsy eyes using various techniques, and resulting scleral indentation was compared to a control series. Indentation was decreased by suture separation narrower or wider than 8 mm, short suture passage, loose sutures, high intraocular pressure, and partial thickness sponges. Increased indentation resulted from excessively tight sutures and low intraocular pressure. No change was produced by variation of sponge stretch or lengthening scleral suture passage. Lateral adjustability of sponge position was gained when wide suture separation was used.
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A retained intraocular foreign body can cause progressive damage to an eye if not removed. Such removal, whether done with a magnet or with a vitrectomy instrument, is often more successful if surgery is not delayed excessively. A two-instrument intraocular approach for resistant foreign bodies can sometimes be avoided in favor of a simpler one-instrument technique if surgery can be performed in the first few weeks.
A new vitreous scissor combines an immobile shaft and hook with a sliding cutting blade; the blade is angled to trap the vitreous band while it is being cut. A tweezer-action handle is used. This scissors cuts dense membranes while producing only minimal traction on the retina.
A camera for fundus photography can be assembled from a standard indirect ophthalmoscope, a single-lens reflex camera, and a modest amount of easily available additional equipment. This camera can be used to record moderate detail of the posterior portion of the fundus and optic nerve head and can be used in an office, a hospital room, or an operating room.