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Biomedical subjects

E Dykes

Publications and source records attributed to E Dykes.

25 records · Page 2Linked to original sources

Three-dimensional stereotactic anatomy of the human trigeminal nerve nuclear complex.

The trigeminal nuclear complex and its spinal tract extend throughout the greater part of the brain-stem and at medullary levels form the target site for producing stereotactic lesions. This paper describes a method for three-dimensional drawings of this nuclear complex. A stereotactic atlas of the human brain-stem and cerebellar nuclei has formed the data base. The two-dimensional composite transverse sections, at 1-mm intervals have been digitized using an X-Y coordinate plotting microscope. Computer programs have been written to generate drawings of a single transverse hemisection as well as regeneration of the opposite hemibrain-stem section. Specific programs were used to reconstruct serial transverse section outlines and incorporate the trigeminal nuclear complex with and without hidden line removal techniques and colour graphic display facilities. Rotation about the x, y and z axes was possible and permits any view of the reconstructed specimen to be computer-generated. A further program for reconstructing structures as stereopairs is presented.

Brain Mapping↗

The use of a digital imaging technique to aid bite mark analysis.

Criminal cases occasionally involve the analysis of bite mark injuries. This paper presents a method of digital image enhancement of an injury and an overlay production method to improve the comparison between the dentition of a suspect and the image of the injury. A comparison method entirely within the digital image software is also illustrated. The use of digitally-produced overlays appears to provide a more objective method of comparison. The use of this method for shoe print, tyre mark and other blunt instrument injury analysis is noted.

Acetates↗

Applications of a microcomputer-based reconstruction system to produce realistic three-dimensional shaded images from serial sections.

A microcomputer-based system is described that generates three-dimensional shaded images from serial section data. It is implemented on the IBM PC-AT microcomputer, using a graphics display card (Real World Graphics PC 4000) to provide sufficient colours for the production of realistically shaded and highlighted images. Image generation time is typically less than 10 min. The capabilities of the system are illustrated by reconstructions of the Kurloff cell from the guinea-pig (based on serial electron micrographs), human teeth (based on light microscope data), the human leg (from gross anatomical sections) and the human brainstem (from stereotaxic atlas data). The system is applicable to a wide variety of serial section data from histological, anatomical and medical imaging systems and ultrastructural studies.

Animals↗