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Biomedical subjects

E Durante

Publications and source records attributed to E Durante.

54 records · Page 3Linked to original sources
PubMed1977

[Ultrasonic diagnosis of aneurysms of the abdominal aorta].

The principles of ultrasound diagnosis are briefly explained and the technique of the examination is described with particular reference to the measures taken to ensure the exact measurement of diameters. The modalities for the echographic presentation of the normal and aneurysmatic aorta is illustrated, together with the respective pictures. It is suggested that echography be employed both as a preliminary technique and as a supplement to angiography, which is not itself particularly applicable in the case of aneurysms. Above all, it can be considered as the sole and resolutive examination on account of the findings it offers.

Angiography↗
PubMed1976

[Tumors of the head of the pancreas. Echographic diagnosis].

The diagnostic possibilities in cancer of the head of the pancreas offered by radiography, angiography, isotopic and endoscopic investigations (with respective accuracy percentages) are examined and a new technique based on the use of ultrasounds is presented. Echography exploits the different structures of tissues by reflecting the ultrasound beam which strikes them in a different way, providing a bidimensional tomographic picture of the surface explored with echostructural profiles and characteristics of the organs. The personal series, together with pictures and percentages of correct diagnosis, is presented. It is concluded that the technique is one of the most suitable for exploring the pancreatic region.

Aged↗
PubMed1976

[Indications and limitations of ultrasonic investigation in abdominal pathology].

Investigation of the abdomen by ultrasounds must now be included among routine tools in abdominal diseases. All abdominal organs, with the exception of the intestine with its gas content, are open to investigation with this technique which combines harmlessness and rapidity with its unique possibility of making differential diagnosis possible in structures with different tissue constitution. The limitations are to be sought more in the examiner's interpretational capacities and in the apparatu's limited resolution power rather than in the technique proper.

Abdomen↗
PubMedDate not supplied

High-dose chemotherapy in small-cell lung cancer.

Small cell lung cancer (SCLC) is highly sensitive both to radiotherapy and chemotherapy. Given its high chemo sensitivity, even two decades ago, SCLC was one of the first malignancies deemed suitable for maximising the dose and dose intensity with the support of autologous bone marrow (ABMT). On the whole, results were disappointing and the procedure was practically abandoned. Nowadays some interest is again emerging due to improvements in supportive care, such as the availability of hematopoietic growth factors and the peripheral blood progenitor cells (PBPC). Data of 505 patients included in 26 studies were reviewed. About two thirds of these patients had LD (limited disease). Late intensification protocols were used in 311 patients who, however, represented only the 30% of the population initially given conventional chemotherapy. Of the patients not achieving complete remission (CR) after induction, high-dose induced a CR in 39% of the cases. The use of early intensification was reported in 8 studies including 194 patients. The CR rate was 51.5%. Overall, the probability of achieving the CR was 2-3 times higher in LD than in ED (extensive disease). Relapses occurred at the site of the primary in more than half of the cases, showing that the course of the disease was not modified by the use of high-dose chemotherapy. Toxic deaths occurred in 7% of the treated patients, without difference in the two treatment methods. Though the schedules were too variable to draw firm conclusions, the ICE (ifosfamide, carboplatin, etoposide) and the CBP (cyclophosphamide, cisplatin, carmustine) regimens apparently provided better results, with a 2-year survival rate of 30-50% in the LD subset. An european multicenter randomized trial is ongoing. At the present time high-dose chemotherapy is still to be considered experimental treatment, since major problems such as the selection of the patients, doses and timing of chemotherapy and radiotherapy remain unsolved.

Antineoplastic Combined Chemotherapy Protocols↗
PubMedDate not supplied

Immunocytochemical detection of estrogen receptors by staining with monoclonal antibodies on cytologic specimens of human breast cancer.

A study was undertaken to test the possibility of determining the estrogen receptor (ER) content in human breast cancers by staining with commercial specific monoclonal antibodies (MAbs) on cytologic specimens (touch imprints and fine needle aspirates). The aspirates were suspended in a cell culture medium and cytocentrifuged onto slides to preserve their morphologic characteristics and to allow a proper immunocytochemical staining for ERs. MAb staining for ER was also performed on the respective surgical samples. The staining of cytologic samples for ER showed 100% specificity and 95% sensitivity in comparison to the staining of the histologic samples. Moreover, comparison of the percentage of stained cells in the cytologic specimens to the ER content in the respective surgical specimens, as assayed by the dextran-coated charcoal method, showed the MAb staining of cytologic samples to have 94% specificity and 100% sensitivity. These results support the reliability of MAb staining for ERs in cytologic samples and suggest that it could be the assay of choice in particular clinical settings in the evaluation of primary and recurrent breast cancers.

Antibodies, Monoclonal↗
PubMedDate not supplied

[Interposition of a jejunal loop, using the Mouchet-Camey method, in gastric cancer surgery].

A series of 80 patients subjected to total gastrectomy for neoplasia is presented. Interposition of the jejunal loop according to Mouchet-Camey was employed as the reconstruction technique. The advantages of this method are highlighted, with particular reference to the results of a study of the absorption of 125I-oleic acid. The complications associated with the operation and the way in which they can be corrected are described.

Duodenum↗
PubMedDate not supplied

[Biliodigestive anastomoses].

Experience with biliodigestive anastomosis in biliary surgery is reported. About 40 operations, subdivided into hepatojejunostomy, choledochojejunostomy, choledochoduodenostomy, hepaticojejunostomy, cholecystoejunostomy, etc. were performed in the period between 1970 and 1978. Indications for these operations are reported and the techniques adopted described. Complications and results are reviewed for each. A choledochoplasty operation using the serosa of an ansa in Roux fashion and transhepatic drainage is reported.

Biliary Tract Diseases↗
PubMedDate not supplied

[Adrenal hemorrhage in the newborn. Diagnostic problems and presentation of a case].

Adrenal haemorrhage is not an exceptional event in the newborn. The probable predisposing factors are difficult delivery, fetal hypoxia, trombocytopenia and coagulation defects. The recommended therapeutical approach is conservative, even if some Authors prefer surgical evacuation of the haematoma. This report was prompted by our recent experience of a case of unilateral adrenal haemorrhage in a newborn. The methods useful in the diagnosis are thoroughly evaluated and discussed with special emphasis on echography which holds an important position in the early diagnosis of this condition.

Adrenal Gland Diseases↗
PubMedDate not supplied

[Papillo-sphinctero-plasty in benign obstruction of the terminal choledochus].

The indications for papillosphincteroplasty in benign obstruction of the terminal choledochus are explained. This technique is certainly preferable to drainage via a T tube--a method no longer applied in a personal series. Lastly, it is stated that the primary transduodenal approach is better than that via choledochotomy. Excellent results were obtained in 62% of cases, good results in 31%, and poor results due to recurrent cholangitis in 3%. Acute pancreatitis is the most dangerous complication, but was very rarely observed.

Ampulla of Vater↗
PubMedDate not supplied

[Ultrasonically-guided percutaneous nephrostomy].

Ultrasonically-guided percutaneous nephrostomy using Seldinger's technique is the most accurate and reliable procedure for pelvic catheterisation in obstruction-induced hydronephrosis. The procedure is straightforward and independent of renal function. Post-renal uraemia may thus be measured and corrected; hydropyonephrosis drained prior to surgical operation of choice. Injection of contrast media may identify an anatomo-pathological situation which cannot be defined with i.v. or retrograde pyelography.

Humans↗
PubMedDate not supplied

[Early diagnosis of breast tumors:/is echography conclusive?].

The use of ultrasonic scanning in examination of the breast is discussed. It is felt that this method is the best that science can offer at present for this purpose, its superiority lying in its diagnostic dependability (90-95% exact diagnoses), low detectability limits (lesions of 5 mm can be diagnosed), suitability for the examination of breast of every age and size, complete freedom from risk, and systematic repeatibility.

Adenofibroma↗