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E Drapier-Faure

Publications and source records attributed to E Drapier-Faure.

13 recordsLinked to original sources
PubMed1992

[Hormonal assessment in a woman with acne and alopecia].

Acne, androgenogenetic alopecia, hyperseborrhea and hirsutism may result from hyperandrogenism in women. This may be peripheral "idiopathic" hyperandrogenism due to cutaneous metabolism of steroids, but in some cases hyperandrogenism is due to abnormal production or input of steroids with androgenic activity (hyperplasia, endocrine tumors, cysts, consumption of progestogens or other hormones with androgenic activity, menopause...). An assessment is useful only in cases of acne or alopecia if they are accompanied by other signs of peripheral hyperandrogenism and/or disturbed menstruation. The treatment is based on the administration of an anti-androgen (in France, usually cyproterone acetate), combined with other local or systemic treatments for the problem, depending on the age, dermatological signs and context.

Acne Vulgaris↗
PubMed1991

[Purified FSH in small doses. Is this not the best current treatment of polycystic ovaries resistant to clomid? 73 cycles].

Sixteen infertile women with the Polycystic ovary syndrome were treated using stimulation of ovulation with purified FSH after Clomid had failed. We compared the results of giving a short course (19 cycles) with giving a long course (54 cycles). With the long course there were fewer cases of hyperstimulation--2 out of 54 cycles (3.70%) as against 1 in 19 cycles with a short course (5.26%). There were fewer changes in the programme needed--6 out of 54 cycles (3.7%) as against 7 cycles out of 19 (31.57%). Ovulatory cycles occurred more frequently in 46 out of 54 cycles (85.18%) as against 12 out of 19 (63.15%). In the long courses 14 pregnancies out of 46 ovulatory cycles occurred (30.43%) as against 3 pregnancies out of 12 cycles (25%). The level of successful pregnancy was much higher in couples who had no other sterility factors--85.10% for the long course as against 63.15% for the short course. In summary purified FSH is an excellent treatment for ovarian dysfunction that is resistant to Clomid. It is necessary to have 3.41 ovulatory cycles to obtain a pregnancy. In this work there were no multiple pregnancies out of the 17 pregnancies and the 3 cases of hyperstimulation that were noted were moderate.

Adult↗
PubMed1989

[Prevention of iatrogenic hyperandrogenism].

The androgen effect of some hormonal compounds are sometimes hidden behind a nomenclature or associations. It is necessary to know how to decipher these messages, confusing at times, in order to have a clear idea of the nature of the compounds which are prescribed.

Androgens↗
PubMed1988

[An evaluation of sterility today].

After a reminder of the epidemiology: fertilization ability, fertility, hypofertility, the classic work-up of a sterile couple will be presented: temperature, hormonal evaluation, sperm count, cervical secretions, PCT, hysterogram. With each examination, a critical study of the evaluation of the results will be developed and possibly new ideas will be approached. Such a review reveals, most of the time, the etiology of the sterility. If this is not the case, after systematic laparoscopy, the rate of unexplained sterility will be approximately 5 p. cent. This small number of "unexplained sterilities" could then benefit from the most sophisticated new techniques, especially in-vitro fertilization of which the results, in terms of pregnancy, are identical in tubal pregnancies and unexplained pregnancies.

Cervix Mucus↗
PubMed1988

[Thermography of the breast. Sensitivity, specificity and reproducibility].

Thermography is a questionable method of diagnosis of breast diseases. In our study, we demonstrate that the low sensitivity and specificity is not related to the experience of the reader. One hundred thermograms were given to five different readers: three of them were thermographists, one was a gynecologist and the last one radiotherapist. Sixteen patients had a breast carcinoma, 18 had benign lesions. Seventy-two patients had no lesion at the time of diagnosis and 4 years after. The false negative and the false positive rates were not different according to the readers. The reproducibility, judged with the Kappa test, was poor. This study, in agreement with most of the previous studies, demonstrates that thermography must not be recommended neither for diagnosis nor for screening of breast diseases.

Breast Neoplasms↗
PubMed1987

[Observations on the new progestational agents].

The purpose of this article will be to present informations regarding two new progestational++ medications: nomegestrol acetate (Lutenyl), and promegestone (Surgestone) in order to make use of them in our prescription habits. We will situate them in relation to various groups of progestative medications and present their specific properties and their tolerance. Finally, we will demonstrate their role in contraception and their effectiveness in the main indications of progestative medications.

Contraceptive Agents, Female↗
PubMed1986

[A new therapeutic approach to infertility in polycystic ovaries: pure FSH].

Current, improved understanding of the physiopathology of polycystic ovary syndrome offers the possibility of more suitable treatment. Formerly, objectives differed for a given patient: re-establish regular cycles using progestogens or estroprogestogens, reduce hirsutism with antiandrogens, trigger ovulation. Clomid is the inducer of choice, but setbacks occur. Injectable gonadotropins were, in principle, a contraindication due to the high incidence of excess stimulation and multiple pregnancy. The introduction of purified FSH offers another method of stimulation. Severe excess stimulation is eliminated with a suitable protocol involving administration of small doses. This offers hope, but as yet no large-scale trial has been published.

Clomiphene↗
PubMed1985

[Functional hyperprolactinemia].

Treatment remains the same whether there is true idiopathic hyperprolactinemia or microadenomas too small to be detectable by methods of investigation. Bromocriptine has an antitumoral effect and treatment can often be stopped after the disappearance of a microadenoma or even of a larger adenoma. "Cure" of idiopathic hyperprolactinemia is rarer.

Adenoma↗