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Biomedical subjects

E Dournon

Publications and source records attributed to E Dournon.

At least 73 records · Page 4Linked to original sources
PubMed1983

Epidemiological features of Legionnaires' disease in the Paris area.

Although the first French case of Legionnaires' disease (LD) was diagnosed in 1979 and the first six serogroups of L. pneumophila and L. longbeachae serogroup 2 were demonstrated in environmental samples from the Paris area, the incidence of the disease has not yet been evaluated in France. Prevalence of antibodies, as detected by an immunofluorescent assay, in the Paris population of our study ranged from 0.9 to 2.2%. LD was demonstrated in 155 (4.4%) of 3502 patients investigated mainly by serology. In a prospective study in a respiratory intensive care unit 20 (7.8%) cases of pneumonia out of 257 were caused by L. pneumophila. 171 of the 175 cases of LD diagnosed in Paris during 33 months were caused by L. pneumophila serogroup 1. Risk factors and epidemiological features of patients are similar to those described in other countries.

Adult↗
PubMed1983

[Legionella pneumophila pneumopathy in a 4 1/2-month-old infant].

A 4 1/2 month-old infant presented with severe alveolo-interstitial pneumonitis needing intubation and mechanical ventilation. Legionella pneumophila infection was established by a significant increase in antibody titers. The clinical picture was consistent with that of legionnaires' disease. No immune defect could be proven.

Female↗
PubMed1982

[Adenine arabinoside treatment of varicella and generalized herpes zoster in 43 immunosuppressed patients].

Forty-three immunosuppressed patients presenting with varicella or generalized herpes zoster were treated with adenine arabinoside (as monophosphate in 10 patients). All those who received the recommended 5-day course were rapidly cured without relapse; the skin lesions were virus-free after the 5th days of treatment. Five patients with malignant varicella involving several organs and who had only been treated for a few hours died. It is concluded that adenine arabinoside is a useful drug in VZ virus infections, although it has no immediate action. The monophosphate presentation, more soluble and requiring lesser amounts of solvent, is easier to administer and as effective as the ordinary presentation.

Adolescent↗
PubMed1982

[The bacteriological and immunological diagnosis of Legionnaires' disease].

There has been very rapid progress in knowledge concerning Legionnaires' disease and the Legionella. Relatively simple and reliable diagnostic techniques are already available. Isolation of Legionella is now possible as a result of the development of sensitive and specific culture media. Detection of the organism in pathological material by direct immunofluorescence leads to emergency confirmation of the diagnosis in approximately 50% of cases. Finally, serology using a specific antigen often leads to a suspicion of Legionnaires' disease a few days after its clinical onset. It provides late confirmation in the immense majority of cases. These three techniques will no doubt be followed by others which will further facilitate the recognition of Legionnaires' disease, a not uncommon and grave illness.

Antibodies, Bacterial↗
PubMed1981

[Plasmodium falciparum malaria resistant to polychemotherapy. Usefulness of pathogen culture (author's transl)].

In a patients with P. falciparum malaria contracted in Thailand, the course of the disease under treatment suggested resistance to both chloroquine and pyrimethamine-sulfadoxine, as well as reduced sensitivity to quinine. This was confirmed by in vitro tests on continuous culture of the strain. Therapeutic success was obtained with a quinine-cycline combination. The problems raised by the emergence of P. Falciparum strains resistant to polychemotherapy are emphasized.

Adult↗