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E Dorrepaal

Publications and source records attributed to E Dorrepaal.

2 recordsLinked to original sources

[Stabilisation therapy as an answer to complex post-traumatic stress disorder. Diagnosis, treatment and research in women abused in childhood with a complex post-traumatic stress disorder].

Complex post-traumatic stress disorder resulting from traumatic experiences in childhood includes not only the customary post-traumatic stress disorder symptoms such as intrusions, avoidance and hyperarousal, but it also includes affect-dysregulation, dissociation, problems with self-image, relationships, interpretation and somatisation. The specialist literature expresses some support for stabilisation treatment. Preliminary results of a pilot study that evaluated a stabilisation course with a psycho-educational and cognitive behavioural content indicate that a course of that kind, if linked to research, is both feasible and effective. We therefore believe that further research by means of a randomized controlled trial is warranted.

Adult↗

Fructans interact strongly with model membranes.

Bacterial fructans with a high degree of polymerisation cause a very large increase in surface pressure of lipid monolayers at the air-water interface with a broad range of lipids, including phosphatidylethanolamine and several types of phosphatidylcholines. The surface active effect of fructans contrasts strongly with the maximal effects observed for trehalose, sucrose and glucose under comparable conditions (20 and 0.6 mN/m for fructans and the other sugars, respectively). The results demonstrate a profound and specific membrane interaction of the fructans which is probably very different from the effect of the smaller carbohydrates. The fructan concentrations used in this study are within the physiological range observed in fructan-accumulating plants. The suggested water-stress protective effect of fructans may be induced by membrane-fructan interaction which prevent lipid condensation and phase transitions to take place.

Bacillus subtilis↗