Biomedical subjects
Publications and source records attributed to E De Santis.
The clinico-radiologic and histopathologic features of 40 osteoid osteomas and 12 osteoblastomas are compared. The authors conclude there are no significant differences between these two tumors except for the size of the neoplastic area and the degree of evolution of the neoplastic tissue.
Eleven cases of malignant fibrous histiocytoma of bone observed during recent years are reported. An analysis is presented with regard to sex, age, site, symptoms, radiography, macroscopic and microscopic aspects. The differential diagnosis is discussed on the basis of these criteria. Because of the small number of cases and limited follow up, it was not possible to come to any definite conclusions concerning prognosis and treatment. Treatment was surgical in almost all the cases.
The author records a case of ossifying periostitis of the tibia apparently due to erythema nodosum. This does not appear to have been recorded previously. The histology, aetiology and differential diagnosis are discussed. The mechanism is probably one of direct spread from skin to periosteum.
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