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Biomedical subjects

E Dahl

Publications and source records attributed to E Dahl.

At least 199 records · Page 11Linked to original sources
PubMed1978

Cell kinetics of mouse urinary bladder epithelium. III. A histologic and ultrastructural study of bladder epithelium during regeneration after a single dose of cyclophosphamide, with special reference to the mechanism by which polyploid cells are formed.

In order to see whether the polyploid cells lining the mouse urinary bladder are formed by nuclear fusion, such epithelium was studied under the light and electron microscope forty-eight hours after an injection of cyclophosphamide when the bladder epithelium regenerates with rapid formation of many diploid, tetraploid and octoploid cells. The probability of seing fusion, if it occurs, ought then to be high. Serial sections of many specimens from four mice revealed no signs of fusion. Thus we found no support for the theory that polyploid cells are formed by nuclear fusion.

Animals↗
PubMed1978

Critical polytraumatization of a patient by a low-velocity gunshot. Case report.

A case report of a 15-year-old boy hit by a single low-velocity gun shot is presented. He sustained injuries to the small bowel, colon, appendix, iliac vessels, femoral nerve and ureter. The injury mechanism and the treatment are discussed, and the importance of exploring a retroperitoneal hematoma is emphasized.

Abdominal Injuries↗
PubMed1976

The ultrastructure of the accessory sex organs of the male rat. XI. Nuclear alterations of prostatic epithelial cells induced by castration.

The fine structure of the nuclei of epithelial cells of the dorsal lobe of the rat prostate were studied 2, 3, 5, 7 and 21 days after castration. The nucleolus appears to undergo a progressive disorganisation with partial fragmentation and dispersion of its normal components. Changes in the nucleoplasm were primarily reflected by a condensation of chromatin, particularly along the nuclear membrane and adjacent to the nucleolus. Later, different types of intranuclear inclusions were observed. After 21 days, the nuclei were characterized by an irregular outline with large indentation. Within the nucleoplasm aggregates of coarse granular chromatin were found. No cell necrosis was observed, indicating that androgen deprivation results in a remodeling of the cell to a less active state with marked cellular alterations and cessation of secretion, but apparently with some of their basic functions still intact. Injections of testosterone completely reverse the castrated-induced alterations. The changes observed are assumed to be due to the withdrawal of the androgenic stimulus, with a direct influence on the secretory function of the cell. The findings support the view that the stimulating secretory effect of androgen is mediated via an intranuclear androgen receptor, probably located in the nucleolus-associated-chromatin. It is also proposed that the secretory function of the epithelial cells of the prostatic complex, initiated by androgens, may be regulated by an intranuclear secretory center.

Animals↗
PubMed1976

Craniofacial morphology in the nevoid basal cell carcinoma syndrome.

A roentgencephalometric analysis of eight males and four females with nevoid basal cell carcinoma syndrome (NBS) is presented. The patients were 14-54 years of age. Fourteen angular and 26 linear variables were measured and compared with control data. The main roentgencephalometric features were: proportionate increase of the size of the calvarium, protrusion of the frontal and parietal region, low position of the occipital region, increased interorbital distance, increased length of the mandible, mandibular retrognathia due to changes in shape and position of the mandible. The suggestion of a characteristic craniofacial morphology as a part of the syndrome was substantiated. Together with other skeletal aberrations the roentgencephalometric findings seemed to indicate that the syndrome is a dysostosis of generalized type.

Adolescent↗
PubMed1976

The Vater association: malformations of the male external genitalia.

Eight cases with the VATER association of malformations are presented. Maliformations of the external genitalia were found in 3 out of 7 male patients. Two of them presented with a bifid scrotum and a caudally displaced, dysplastic penis. Two patients had been exposed to progestin in early pregnancy and one of them had hyposadias and testicular atrophy. It is suggested that malformations of the male external genitalia might be part of malformations found in the VATER association.

Abnormalities, Multiple↗
PubMed1976

Flexor tendon synovectomy of the hand in rheumatoid arthritis. A follow-up study of 201 operated hands.

A follow-up study of 201 flexor tendon synovectomies of the hand in patients with rheumatoid arthritis is presented. The operations were performed from 1/2-49 years after onset of the disease, and the patients were between 16 and 76 years of age. The follow-up study is based on questionnaires and, in addition, 78% of the patients also had a physical re-examination. The follow-up time spanned 12-78 months. Nearly 70% of the operated hands were subjectively improved; the others were unchanged or worse. The poor results were often caused by progression of arthritis in finger joints. Recurrence of the tenosynovitis was observed in about 37% of the hands, but in very few to such an extent that reoperation has been necessary.

Arthritis, Rheumatoid↗
PubMed1976

Wear of the polyethylene head of the Oscobal prosthesis.

Ten hemiarthroplasties were performed with the Oscobal (Daubenspeck) his prosthesis, which consists of a metal stem and a nonrotating ployethylene head. Five patients died 1-150 days after the operation. Signs of massive wear of the polyethylene head were demonstrated in four out of the five patients still alive 16-28 months after the operation. We can therefore not recommend the Oscobal system for hemiarthroplasty of the hip.

Aged↗