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Biomedical subjects

E D Matiushina

Publications and source records attributed to E D Matiushina.

7 recordsLinked to original sources
PubMed1980

[Liver regeneration in mice after a partial hepatectomy under the action of blood serum and of an extract of cirrhotically altered human liver].

The effects of blood serum and liver extracts from patients with chronic active hepatitis and liver cirrhosis on the mitotic rate of the mouse liver regenerating after partial hepatectomy were comparatively studied. It is suggested that the livers of patients suffering from active cirrhosis produce a factor which is capable of stimulating the mitotic activity of hepatocytes.

Animals↗
PubMed1976

[Liver chalones].

Administration of a liver extract and the blood serum of adult intact mice and also of the blood serum of practically healthy persons to CBA X C57B1 hybrid mice produced a sharp depression of the mitotic activity of hepatocytes in the regenerating liver after its partial removal. The extract of the regenerating liver and the blood serum of the animals with the regenerating liver failed to depress mitoses in hepatocytes. The blood serum of man with the postnecrotic active cirrhosis of the liver not only failed to depress mitoses in the hepatocytes, but even caused an increase in their count. It is supposed that there was a reduction of the chalone concentration in the cirrhotic liver.

Animals↗