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Biomedical subjects

E D Lowney

Publications and source records attributed to E D Lowney.

At least 19 recordsLinked to original sources
PubMed1987

Ground reaction forces during ambulation in parkinsonism: pilot study.

Gait abnormality in parkinsonism is unique and easily recognizable. A pilot study was designed at our Human Gait Laboratory to learn how this gait abnormality is reflected in ground reaction forces of patients with parkinsonism. The system permitted the collection of kinematic and force data from a subject in real time. Analysis showed an abnormality in the vertical force (Fz) component, the second peak being significantly reduced in size, with asymmetry in the duration of the stance phase. These abnormalities were also reflected in the stance phase and in the angular changes in the knee. Similar analyses should be helpful in following the progress of the disease.

Gait↗
PubMed1982

Increased helper-suppressor T-cell ratio in psoriasis.

Numerous investigations have suggested an immunologic pathogenesis of psoriasis and diminished suppressor T-cell activity of psoriatic blood. Consequently, a study was undertaken to explain whether diminished suppressor cell activity was a result of quantitative alterations of the T-lymphocyte subpopulation. Twenty patients with psoriasis and 20 normal control subjects were randomly selected. Our findings demonstrated a significant decrease in the percentage of suppressor cells (T gamma), a significant elevation of helper cells (T mu), and a highly significant increase in the helper-suppressor T-cell ratio (T mu/T gamma) of psoriatic blood compared with that of normal control subjects. Our study gives further support to the possible role of immunologic factors in the pathogenesis of psoriasis.

Adult↗
PubMed1979

Folded skin associated with underlying nevus lipomatosus.

A mentally retarded female infant had abnormalities of the feet, hemiplegia, and an underlying nevus lipomatosus. To our knowledge, this represents the second reported case of marked folding of the skin; with an underlying nevus lipomatosus; this case demonstrated an association of this cutaneous disorder with multiple defects, including chromosomal abnormalities, which have not been previously reported.

Child, Preschool↗
PubMed1978

Progressive cribriform and zosteriform hyperpigmentation.

Five cases of progressive cribriform and zosteriform hyperpigmentation are described. The following criteria were fulfilled: (1) uniformly tan cribriform macular pigmentation in a zosteriform distribution; (2) a histologic pattern that consisted of a mild increase in melanin pigment in the basal cell layer and complete absence of nevus cells; (3) no history of rash, injury, or inflammation to suggest postinflammatory hyperpigmentation; (4) onset well after birth with gradual extension; and (5) lack of other associated cutaneous or internal abnormalities. This appears to be a newly described entity, although it resembles a Becker's nevus without hypertrichosis or an typical café au lait spot. We believe that such progressive cribriform and zosteriform pigmentation is not uncommon.

Adolescent↗