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Biomedical subjects

E D Koulentianos

Publications and source records attributed to E D Koulentianos.

5 recordsLinked to original sources

Radiation doses to patients undergoing standard radiographic examinations: a comparison between two methods.

The objective of the study was to derive a mathematical method for calculating the entrance surface dose (ESD) from exposure factors for all tube potentials used in clinical practice and to compare the calculated ESDs (ESD(C)) with those measured (ESD(TLD)) using thermoluminescent dosemeters (TLDs). The exposure parameters of 43 patients who underwent (a) posteroanterior (PA) and lateral (LAT) chest examination (13 patients), (b) supine abdomen (10 patients), (c) erectus abdomen (10 patients), or (d) urinary tract examination (10 patients) were recorded. Patient ESD was directly measured by TLDs and calculated from exposure factors. The differences between ESD(C) and ESD(TLD) were quite small and could be explained by the uncertainties involved in both methods, in all but the PA chest examination where the ESD(C) was about 50% larger than ESD(TLD). However, in PA chest the ESD(TLD) was close to the minimum detectable dose of TLDs, questioning the accuracy of ESD(TLD). Further investigation showed that using the high tube potential technique (130 kV) in the PA chest examination resulted in very short exposure times, in the region of 4 ms. In such short exposure times, the X-ray generator operation presented stability problems that led to loss of output linearity and consequently to false calculation of ESD. The calculation method offers a reliable and cheap alternative to the measurement of ESD by TLD, provided that the exposure times are not as short as in the PA chest examinations recorded in this study, so that the output linearity with tube current-time product (mAs) is maintained.

Body Weight↗

Radiation doses to patients from enteroclysis.

The purpose of this study was to determine the patient doses during enteroclysis and compare them with the available bibliographical data. For 14 enteroclysis examinations, the dose-area product (DAP) meter readings, fluoroscopy time, number of radiographs and exposure data were recorded. From these data, the fluoroscopy and radiography contributions to DAP, the entrance surface dose (ESD) and the effective dose (E) for each examination were estimated. The mean DAP was 81 Gy cm(2) and the mean fluoroscopy time was 19.5 min. The fluoroscopy contribution to DAP was 77% and 8.7 films were acquired in each examination on average. The mean ESD and E were estimated to be 428 mGy and 21 mSv, respectively. The mean DAP and fluoroscopy time calculated in this study are quite high when compared with those reported in the literature, suggesting that the examination technique should be reviewed and the ways to reduce patient exposure without compromising the diagnostic quality should be acquired.

Adult↗

Threshold selection in virtual bronchoscopy: phantom study and clinical implications.

PURPOSE: To investigate the effect of the threshold selection on the apparent diameter of a virtual bronchus and the virtual wall morphology and to examine the parameters that can affect the selection of the appropriate threshold for virtual bronchoscopy with single slice computed tomography. MATERIAL AND METHODS: A bronchial phantom containing plastic tubes simulating the airways of the tracheobronchial tree was constructed. The diameters of the virtual images of these tubes were measured using various thresholds for two different materials surrounding the tubes: air and water. These measurements were correlated with the density in HU of the walls. Furthermore, data from 20 virtual bronchoscopies in patients were retrospectively analyzed in the same way. RESULTS: The diameter of a virtual bronchus is strongly affected by the selected threshold. The appropriate threshold for accurate diameter representation depends on the density of the bronchial wall. CONCLUSION: Our results suggest that in clinical practice a single threshold value cannot be used for imaging all segments of the tracheobronchial tree. While a value of -520 is appropriate for the trachea and lobar segments, values down to -720 could be needed on the level of segmental and subsegmental bronchi. At these levels, a threshold value about 65 HU more negative than the value where the artificial holes appear on the virtual bronchial walls could be used.

Bronchoscopes↗

Variation of the sensitometric characteristics of seven mammographic films with processing conditions.

The effect of different processing conditions on the sensitometric characteristics of mammographic films was investigated and the implications of this effect on clinical practice are discussed. Three Agfa (MR5-II, HDR and HT), two Kodak (MinR-M, MinR-2000), one Fuji (AD-M) and one Konica (CM-H) single emulsion mammographic films were used. For each film type a 21-step sensitometric strip was developed in seven different processing conditions involving the use of four processors, five developing times and four chemistries. The different processing conditions produced a variable effect on the sensitometric characteristics of the mammographic films. While some films seemed relatively insensitive, others were greatly affected. Furthermore, not all the sensitometric parameters of a film were affected in the same way. For example, a change of processing conditions in some cases increased speed and decreased contrast but in some other cases increased both speed and contrast. Different mammographic films present different sensitometric characteristics that can be altered by processing conditions. Thus, in a mammographic facility any change in film processor/processing cycle or chemistry should be carefully investigated before mammograms of patients are acquired. Furthermore, the results of film comparisons under certain processing conditions should not be generalized to other processing conditions.

Female↗

Radiation doses to patients from endoscopic retrograde cholangiopancreatography examinations and image quality considerations.

The purpose of this investigation was to measure the dose-area product (DAP) and the other relevant dosimetric quantities in diagnostic and therapeutic endoscopic retrograde cholangiopancreatography (ERCP). Furthermore, the dependence of patient dose and image quality on the tube potential was investigated. A DAP meter was used for dose monitoring in seven diagnostic and 21 therapeutic ERCPs. For each ERCP the DAP meter readings, fluoroscopy time, number of radiographs and exposure data were recorded. From these data the fluoroscopy and radiography contributions to DAP, the entrance skin dose and the effective dose for each examination were estimated. For the investigation of the effect of tube potential on patient dose and image quality, a water phantom containing syringes filled with diluted contrast media was used. The average DAP was 13.7 Gy cm2 in diagnostic and 41.8 Gy cm2 in therapeutic ERCP whereas the average fluoroscopy times were 3.1 and 6.0 min respectively. DAP was strongly correlated to the fluoroscopy time. Measurements in the phantom showed that a good compromise between image quality and patient dose is obtained for tube potentials around 80 kV. Therapeutic ERCPs deliver on average higher doses to patients than diagnostic ERCPs. However, for a difficult diagnostic ERCP more patient exposure may be required than for a simple therapeutic ERCP.

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