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Biomedical subjects

E Czakó

Publications and source records attributed to E Czakó.

12 recordsLinked to original sources

Effect of the stellate ganglion blockade upon the electrical systole (Q-T interval) of the heart.

The effect of the Novocain blockade of the stellate ganglion upon the duration of the electrical systole (Q-T) of the heart was studied in 38 patients. Basic Q-T was normal in 17 patients; in these cases stellate ganglion blockade did not influence the Q-T interval. Of the 21 cases with Q-T prolongation, in 10 the Q-T interval became considerably shorter upon the effect of blockade. In the 11 cases that did not respond to the blockade, ECG repolarization was regular, and there was no arrhythmia. Of the 10 responsive cases with Q-T prolongation, in 9 the repolarization was pathological, and in 6 there was no chronic arrhythmia. The authors discuss the role of the sympathetic nervous system in certain forms of Q-T prolongation.

Adult

[Effect of electric cardiac stimulation in experimental supraventricular tachycardia].

Experimental supraventricular tachyarrhythmia was produced in dogs by the local application of aconitine on the left auricle. The effect of various types of stimulations (right auricular, right ventricular, double-delayed right auricular and right ventricular-right auricular double-delayed stimulation) was studied for the suppression of supra-ventricular (overdrive) tachyarrhythmia. It was found that the electric stimulation of the heart is an effective method of suppressing tachyarrhythmias, though there is a significant difference in the anti-arrhythmic effects of the electric stimulations of various types. For suppression of the supraventricular tachyarrhythmia caused by aconitine, delayed double-right auricular stimulation seemed to be the most effective with respect to the right ventricle. The bioelectric features of aconitine arrhythmia and the mechanism of the antiarrhythmic effect of the electric stimulation of the heart are discussed.

Aconitine

Effect of ethyl apovincaminate on the cerebral circulation. Studies in patients with obliterative cerebral arterial disease.

The effect of ethyl apovincaminate (RGH-4405, Cavinton) on the cerebral and systemic circulations has been studied in detail in ten cases of cerebrovascular disease. 10 mg doses of Cavinton were given as infusion within 4-6 min; circulatory tests were carried out prior to administration of the drug and 3-6 min after. The principal results showed the following: On Cavinton cerebral vascular resistance was strongly reduced, while cerebral fraction of cardiac output significantly increased. On acute effect of the drug arterial mean pressure slightly decreased but cerebral blood flow nevertheless increased in general. Total vascular resistance also decreased but this decrease was less marked than that registered in cerebral vascular resistance.

Adult

[Diagnostic angiography in mediastinal and pulmonary diseases].

The angiographic methods employed in chest surgery are reviewed and their value is demonstrated on practical examples. In certain cases angiography is the only means of arriving to the correct diagnosis and its result often determines the course of therapy. Angiographic methods are claimed to be equivalent to the classical diagnostic procedures applied in pulmonology and their wide-spread use is recommended.

Adolescent