Phage-typing of S. typhi is considered a valid tool for epidemiological studies on typhoid fever, and has therefore been used for many years at the Reference Center for Phatogenic Enteric Bacteria of Northern Italy. Results obtained from Jan 1 1980 through April 30 1981 are reported and a temporal (with what was obtained at the Center in the past) and geographical (with the results obtained by the Reference Centers for Central and Southern Italy) comparison are performed with the results obtained by this Center in the past and by other Centers both in this Country and abroad.

Epidemiologic Methods↗

PubMedDate not supplied

[Electronic organization in the management of a central reference for pathogenic enterobacteria].

Since 1978 as a pilot study and, since 1979 in routine way, an epidemiological form is used at the Reference Center for Pathogenic Enteric Bacteria of Northern Italy; it accompanies all strains of enteric bacteria sent by hospital, clinical and public health laboratories. Results obtained through the use of this form from 1979 through June 1981 are reported and the steps of the computerized management of the Center and of the Bacteriological Laboratory of the University Hospital of Milan are illustrated.

Computers↗

PubMedDate not supplied

Chlorpromazine-induced decrease of red cell aggregability.

Starting from the assumption that binding of chlorpromazine to the erythrocyte membrane might influence th rheology of these cells, the authors studied erythrocyte aggregability and deformability by means of a filtrability test in 42 neurotics and 16 patients with personality disorders, all males, aged 20 to 27 years, clinically healthy from the somatic view point. Determinations were carried out before and 30 min after a single i.m. dose of 1 mg/kg b.w. chlorpromazine (14 patients) and before and after a 5-day oral treatment with 3 mg/day haloperidol (11 patients) or 75 mg/day chlorpromazine (33 patients). Chlorpromazine induced a significant decrease of erythrocyte aggregability after 5 days of oral treatment (p less than 0.02) the effect being more marked in the patients with relatively high initial values (p less than 0.01). The mechanism of this phenomenon and its possible implications of ESR determination and in the therapy of occlusive vascular diseases are discussed.

Adult↗