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Biomedical subjects

E Conradi

Publications and source records attributed to E Conradi.

14 recordsLinked to original sources

Effects of continuous and pulsed microwave irradiation on distribution of heat in the gluteal region of minipigs. A comparative study.

Eleven experiments were conducted on minipigs for the purpose of determining heat distribution in tissue exposed to therapeutic doses of microwaves. Temperatures were measured by means of coated thermocouples from the cutis, subcutis, musculature, and periost. Irradiation was applied to intensities of 10 W, 40 W and 60 W by means of a "Radarmed 12 S 251" circular emitter and to 60 W, 100 W and 140 W, using a trough emitter. Maximum temperature in superficial tissue layers was reached after five to ten minutes of microwave exposure. The temperature rise in the cutis and subcutis was steeper and at a higher rate than that in the muscles. Continuation of microwave irradiation did not cause any further rise in temperature, which was attributed to induction of hyperaemia. No difference regarding heat distribution was found to exist between pulsed and continuous irradiation at equal wattage.

Animals

[Physical therapy in chronic obstructive lung diseases].

Based on the definition of physiotherapy as having functional orientation aiming to stimulate reactive processes of body itself, the position of physiotherapy is outlined. The most important methods for the treatment of the bronchitic syndrome are described. Their mode of action, target, and dose are explained. In practice, physiotherapy should be applied as a complex series of treatment.

Bronchitis

[Status of physical therapy in the treatment strategy of internal diseases].

The use of physiotherapy as traditionally successful form of therapy is not in the least satisfying in practice. The reasons for this are explained. Issuing from a general assessment of the therapy in the system medical care, principal aspects for an interdisciplinary therapy are demonstrated. Essential for a scientifically proved use of physiotherapy is the differentiation between general and specific aspects in the pathologic process made in the general nosology. The effects of the physiotherapy are shown and its significance as basis therapy is emphasized. Apart from the knowledge of the individual physiotherapeutic remedies, the use of the physiotherapy has as its prerequisite a valuation of the pathogenetic factors and actual additional conditions. Corresponding to the therapeutic aim, the physiotherapy should be conceived either as monotherapy or as a long-term, frequently multi-dimensional therapeutic programme. Essential errors in practice are the technically insufficient and inconsequent use of the treatment capacities. With the help of the recommendations for the use of the physiotherapy in the essential hypertension and rheumatoid arthritis ways are indicated how the potencies of the specialty are to be realised better than hitherto done in chronic diseases.

Arthritis, Rheumatoid

[Experiences gained from the establishment of a complex physical therapy program for the management of female urinary incontinence].

Reported in this paper are preliminary experiences so far obtained from a complex physiotherapeutic programme for conservative and pre-operative treatment of functional urinary incontinence in women. Included in this pilot study were 82 patients of whom 23 (28 per cent) were continent on termination of the therapy, while another 38 (46 per cent) had improved to an extent where they abandoned their original intention to undergo surgery for incontinence. Complex physiotherapy may add favourably to the spectrum of possible therapeutic approaches, provided its proper and differentiated coordination with the generally known surgical approaches.

Electric Stimulation Therapy

Simultaneous determination of propranolol and 4-hydroxypropranolol in plasma by mass fragmentography.

A quantitative method for the simultaneous determination of propranolol and its active metabolite 4-hydroxypropranolol in human plasma is described. Plasma samples are extracted at pH 9.6 with ethyl acetate after the addition of sodium bisulphite and the internal standard oxprenolol. The extracts are derivatized with trifluoroacetic anhydride before separation on a gas chromatograph--mass spectrometer. Detection and quantitation of the trifluoroacetyl derivatives are made by single-ion monitoring. The minimum detectable concentration of propranolol is 1 ng/ml and of 4-hydroxypropranolol 5 ng/ml using 1-ml plasma samples. No interferences from normal plasma constituents or from drugs commonly prescribed together with propranolol were detected.

Chromatography, Gas