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Biomedical subjects

E Confino

Publications and source records attributed to E Confino.

61 records · Page 4Linked to original sources

Treatment of minimal and moderate intrauterine adhesions (Asherman's syndrome).

Fifty-one women with only minimal and moderate intrauterine adhesions (Asherman's syndrome) underwent dilatation of the cervix, lysis of adhesions and insertion of intrauterine contraceptive devices (IUDs). A pregnancy rate of 90% was achieved. In 85% of the pregnancies a viable infant was delivered, and 15% terminated in abortions. No complications of pregnancy or of the third stage of labor were noted. The most common procedure preceding the appearance of intrauterine adhesions was curettage for spontaneous abortion and less frequently for missed and induced abortions. It seems that in mild and moderate Asherman's syndrome, lysis of adhesions and IUD insertion without estrogen administration yield satisfactory results.

Adult↗

Comparison between OM-GA Cu and Copper-T IUCDs.

OM-GA Cu and Copper-T IUCDs were compared in a randomized prospective clinical trial in two-hundred women and followed up for two years. Dysmenorrhea and dyspareunia were more frequent with the Copper-T. Menometrorrhagiae, vaginal discharge and pelvic inflammatory disease were similar with both IUCDs. Two-year pregnancy rate for the OM-GA Cu was 5.4% and 3.2% for the Copper-T. Expulsion rate was 11.9% for the OM-GA Cu and 5.3% for the Copper-T. The OM-GA Cu users had less dysmenorrhea and dyspareunia but a higher expulsion rate compared to the Copper-T.

Adult↗

Transcervical balloon tuboplasty. A multicenter study.

Transcervical balloon tuboplasty represents a noninvasive technique to treat proximal tubal occlusion. In a multicenter study, 77 women with confirmed bilateral proximal tubal occlusion underwent the procedure. In 71 patients (92%), at least one proximally obstructed fallopian tube was recanalized. Concomitant distal bilateral tubal occlusions were diagnosed after successful proximal tubal balloon recanalizations in 13 patients (17%). In the remaining 64 patients, 22 clinical pregnancies (34%) have been confirmed during a median follow-up period of 12 months. Among those, 17 (77%) resulted in normal deliveries and five (23%) resulted in a first-trimester miscarriage. One patient was diagnosed with an ectopic pregnancy. Among 25 patients who had not conceived within 6 months of the procedure, 17 (68%) demonstrated continuing tubal patency on repeated hysterosalpingogram. We conclude that transcervical balloon tuboplasty is a safe outpatient technique that may represent an alternative to in vitro fertilization or microsurgical reanastomosis of fallopian tubes.

Adult↗

Effects of progesterone on postoperative adhesion formation in hysterectomized rabbits.

Progesterone has been reported to have an antiinflammatory as well as immunosuppressive effect, and may prevent adhesion formation. In this study, nine treated and seven control rabbits were randomly selected for either pre- and postoperative progesterone treatment or no treatment. All rabbits underwent hysterectomy, focal peritoneal denudation, and intraabdominal instillation of suspended talc. Adhesion formation was evaluated 1 month postoperatively during repeat exploratory laparotomy. Progesterone-treated and control rabbits did not show any significant difference overall in the incidence of adhesion formation. Subgrouping of adhesion formation into adhesions formed by major surgical tissue trauma or minor peritoneal damage revealed a beneficial effect of progesterone in the reduction of only minor adhesion formation.

Animals↗

The role of severe adnexal disease in tubal reconstructive surgery.

Fifty two consecutive women underwent microsurgical reconstruction of the tubes. Thirty one percent conceived and 19% delivered live infants. Medical history suggestive of pelvic infection was obtained in 44% of the women. Fifty four percent had extensive, coarse and fibrous adhesions. Tubal reconstruction in these patients did not yield any pregnancies. Severity of the adnexal disease should be evaluated before attempted tubal reconstructive surgery. Women with severe adnexal damage should be referred to in vitro fertilization.

Abortion, Induced↗

A system for simultaneous bilateral tubal cannulation.

OBJECTIVE: The efficacy of a new system for simultaneous bilateral tubal cannulation under tactile impression was evaluated. METHODS: Two radiologically detectable selective salpingography catheters (Bard Gynecology and Urology, Covington, GA) were glued back to back in a "T" configuration similar to an intrauterine device. A sliding plastic sleeve contained the straightened catheters and the uterus was cannulated under tactile impression. The sleeve was then withdrawn and the catheters opened within the uterine cavity and wedged into the right and left tubal ostia simultaneously. Selective injection of water-soluble radiologic contrast material into the tubes resulted in selective salpingography and determined successful tubal cannulation. Withdrawal of the catheters back into the sleeve allowed injection of contrast material into the uterine cavity. PATIENTS: The system was evaluated in 14 consenting patients scheduled for hysterosalpingogram during infertility evaluation. RESULTS: Bilateral selective salpingography was achieved successfully under tactile impression in 12/14 (86%) patients. In two patients with either distorted or very small uterine cavity, the catheter tips embedded into the lateral uterine walls and did not selectively cannulate the tubal ostia. Reapplication of the system under fluoroscopy allowed bilateral selective salpingography of these two patients. CONCLUSION: Simultaneous bilateral selective salpingography eliminated the need for cervical cannula, significantly reduced fluoroscopy time to seconds, and demonstrated that tactile cannulation is successful in normal uteri. Application of this system for simultaneous tubal cannulation is identical to intratubal uterine device insertion, a procedure familiar to all gynecologists. Therefore, this catheter system may further contribute to simplification of transcervical access into the fallopian tubes for diagnosis and treatment.

Catheterization↗