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Biomedical subjects

E Coleman

Publications and source records attributed to E Coleman.

At least 73 records · Page 4Linked to original sources
PubMed1980

Nonradioactive iodoantipyrine enhanced cranial computed tomography: preliminary observations.

Nonradioactive 4-iodoantipyrine, an iodinated indicator that freely diffuses across the blood-brain barrier, was serially imaged in vivo using computed tomography (CT). Prominent enhancement was immediately detected in the brain substance of the dog following the intracarotid injection of this contrast medium. An estimate was made of the brain:blood partition coefficient for 4-iodoantipyrine from the CT derived arterial and brain concentration of this iodinated marker. Practical applicability of this technique is limited unless an improved method for getting the 4-iodoantipyrine into solution can be developed. However, this study reinforces the concept that local cerebral blood flow and metabolism can be analyzed by diffusible tracers using CT.

Animals↗
PubMed1979

Microbiologic evaluation of poly-HEMA root canal filling material.

This study was designed to determine whether poly-HEMA root canal filling material can support bacterial growth. Eight different microorganisms were tested against the polymerized material, as well as against the powder and paste components of the unpolymerized material. The results establish that this root canal filling material does not support bacterial growth.

Acrylates↗
PubMed1978

Toward a new model of treatment of homosexuality: a review.

A review of the literature of outcome studies in the psychoanalytic or behavioral treatment of homosexuality reveals limited results when "heterosexual shift" is the goal. Recently, however, a growing body of empirical knowledge has accumulated that challenges the illness or maladaptive model of homosexuality. Consequently, a new model has been emerging that is designed to assist homosexuals to recognize, accept, and value their sexual identity and to help them adjust to this identity in a predominantly heterosexual society. Unfortunatley, only a few studies exist that examine the result of this new approach.

Adult↗
PubMed1975

Cardiac rate and rhythm changes with atropine and methscopolamine.

The effects of methscopolamine bromide (MSB) and atropine were compared in patients prior to elective surgery. After administration of the second dose of MSB (total dose 1.5 mug/kg) all patients exhibited at least 20% increase in heart rate. In contrast, three doses of atropine (total dose 5.3 mug/kg) were required for most patients to attain a 20% increase in heart rate while 2 patients did not attain this heart rate with a dose of 10.6 mug/kg of atropine. Comparison if single injections of MSB and atropine in normal subjects also demonstrated a more reliable dose-response relationship with MSB. Electrocardiographic changes recorded were typical of those reported with anticholinergic agents. Sinus and atrial arrhythmias were more common with atropine and nodal arrhythmias and conduction disturbances were more common with MSB. This study demonstrated that MSB can be reliably substituted for atropine when an anticholinergic drug is needed to increase heart rate. Since MSB has a limited ability to cross the blood-brain barrier, it may be the more desirable drug in patients in whom the central nervous system effects of atropine may be deleterious.

Adult↗
PubMedDate not supplied

Compulsive sexual behavior inventory: a preliminary study of reliability and validity.

This preliminary study was designed to develop empirically a scale of compulsive sexual behavior (CSB) and to test its reliability and validity in a sample of individuals with nonparaphilic CSB (N = 15), in a sample of pedophiles (N = 35) in treatment for sexual offending, and in a sample of normal controls (N = 42). Following a factor analysis and a varimax rotation, those items with factor loadings on the rotated factors of greater than .60 were retained. Three factors were identified, which appeared to measure control, abuse, and violence. Cronbach's alphas indicated that the subscales have good reliability. The 28-item scale was then tested for validity by a linear discriminant function analysis. The scale successfully discriminated the nonparaphilic CSB sample and the pedophiles from controls. Further analysis indicated that this scale is a valid measure of CSB in that there were significant differences between the three groups on the control subscale. Pedophiles scored significantly lower than the other two groups on the abuse subscale, with the other two groups not scoring significantly differently from one another. This indicated that pedophiles were more abusive than the nonparaphilic CSB individuals or the controls. Pedophiles scored significantly lower than controls on the violence subscale. Nonparaphilic individuals with compulsive sexual behavior scored slightly lower on the violence subscale, although not significantly different. As a preliminary study, there are several limitations to this study, which should be addressed, in further studies with larger sample sizes.

Adult↗
PubMedDate not supplied

Anodyspareunia, the unacknowledged sexual dysfunction: a validation study of painful receptive anal intercourse and its psychosexual concomitants in homosexual men.

This study examines the frequency and duration of pain in same-sex anal intercourse in a sample of 277 adult men who have engaged in, or attempted to engage in, anal intercourse during their lifetime. Whereas estimates of frequency of pain appeared blocked distributed across a 7-point Likert scale, severity of pain appeared positively skewed, with 12% rating it as too painful to continue. Participants rated inadequate lubrication, psychological factors such as not feeling relaxed, and lack of digitoproctic stimulation prior to penetration as the three most important psychophysiological factors predicting pain. Factors associated with a greater amount of pain experienced in anal intercourse were depth and rate of thrusting, lack of social comfort with gay men, being more "closeted," and less concern over becoming old or unattractive as a gay or bisexual man. Pain was also positively related to anxiety. The use of condoms was not rated highly as a factor in receptive anal pain. Based on these findings, the authors define anodyspareunia to denote painful receptive anal intercourse, and suggest clinical criteria similar to that used for other sexual pain disorders.

Adolescent↗
PubMedDate not supplied

Bisexual and gay men in heterosexual marriage: conflicts and resolutions in therapy.

This paper describes 31 men who at the time of entering therapy were married and expressed concern about their same-sex feelings and activity. Each of these man was treated in a "bisexuality group" designed to help him to be more comfortable and accepting of his same-sex feelings and to explore ways of incorporating same-sex and opposite-sex feelings into his life. Following treatment, 11 of the 31 men (36%) decided to end their marriage; twenty men (64%) decided to remain married. In a follow up study, there was a further attrition of marriages so that 14 remain married. The paper further describes attitudes and behavior prior to therapy, immediately following therapy, and at the time of follow up (up to three years). Factors that seem to be important ingredients of of successful adjustment are discussed.

Adult↗