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Biomedical subjects

E Coche

Publications and source records attributed to E Coche.

At least 55 records · Page 3Linked to original sources
PubMed1991

[Liver abscess and appendicular foreign body].

We report a case of liver abscess secondary to appendicitis which was due to a wire within the appendix. Appendicitis was asymptomatic, probably because of its retrocaecal position and/or previous antibiotic treatment. The abscess was treated with broad-spectrum antibiotics and percutaneous drainage, followed by a second stage appendicectomy. This case illustrates the value of gastrointestinal radiological investigations before considering the abscess as cryptogenetic.

Adult↗
PubMed1990

Cerebral and renal arterial thromboses in systemic lupus erythematosus with antiphospholipid antibodies: a report of two cases.

Antiphospholipid antibodies have been associated with an increased risk of thromboses, most of which occur in veins. We observed a very unusual association of cerebral and renal thromboses, in 2 patients with systemic lupus and anti-prothrombinase, in whom arterial occlusions were clearly documented. Immunosuppressive treatment was followed by a dramatic improvement in both. In the literature, no treatment clearly prevents the recurrence of these thromboses. This could be partly explained by our current ignorance of their pathogeny.

Adult↗
PubMed1990

Jaundice and intracardiac tumour.

We report the case of a type B lymphoma originating from the mediastinum, characterized principally by massive metastatic invasion of the right cardiac cavities in the form of a projecting mass well visualized at echography responsible of the presenting features of the illness. This lymphoma was, moreover, associated with an auto-immune haemolytic anaemia due to cold agglutinins.

Aged↗
PubMed1990

[Multiple cerebral infarcts in a young man].

The case of a young, male patient hospitalized for investigation of a cerebral vascular accident is reported. The investigations led to the diagnosis of disseminated lupus erythematosus associated with the presence of antiphospholipid antibodies (lupus circulating anticoagulant and anticardiolipin antibody). The authors discuss certain notions relating to antiphospholipid antibodies and the thromboembolic, particularly neurological, manifestations thereof.

Adult↗
PubMed1988

Immune-mediated panniculitis, mimicking pancreatic-disease-associated fat necrosis.

A fifty-seven-year-old woman had been suffering from chronic nodules on both legs for 17 years. The histologic findings have suggested pancreatic-disease-associated fat necrosis. Up to now, however, no pancreatic disorder has been found and several biological clues indicate that a more plausible explanation may be an immune-mediated injury of the panniculus.

Diagnosis, Differential↗
PubMed1987

Klinefelter's syndrome and lupus erythematosus: report of a case.

We report a case of SLE related polyarthritis in a 28 year-old man with Klinefelter's syndrome treated with testosterone for 13 years. Clinical outcome was favorable with low doses of corticosteroids. The pathogenesis of that strange association is discussed.

Adult↗
PubMed1985

A case of cholestatic hepatitis associated with D-penicillamine therapy for rheumatoid arthritis.

A male aged 72 years suffering from erosive seropositive rheumatoid arthritis developed jaundice after one month on D-penicillamine after a cumulative dose of 5.625 g. The biological abnormalities were characteristic of cholestasis. There were no gall-stones. The liver biopsy showed severe intrahepatocellular cholestasis with a slight degree of cellular cholangitis and with eosinophils in the portal tracts. There was no sign of cellular necrosis. After cessation of D-penicillamine, the jaundice cleared within three weeks and the enzymes were normalized within two months. The aetiology is discussed and the cases of the literature are reviewed. This case represents a further instance of D-penicillamine-induced cholestatic hepatitis.

Aged↗
PubMed1984

[Sarcoidosis in internal medicine. A cooperative study of 554 cases].

The authors report the results of a retrospective cooperative study of 554 cases of sarcoidosis admitted to departments of internal medicine. The condition is more common in women (57 p. 100) than men (43 p. 100), but the onset is earlier in men. The clinical presentation is very variable and includes a wide variety of extra-thoracic localisations. "Guided" biopsy of early accessible lesions (skin, subcutaneous lymph nodes) is positive in 92 p. 100 of cases: the sensitivity of "blind" biopsy is less impressive, ranging from 49 to 69 p. 100 according to the tissue biopsied (bronchial mucosa, accessory salivary glands, liver). Alveolar lavage is positive in 65 p. 100, and angiotensin converting enzyme is positive in 58 p. 100 of untreated cases. There is a clear correlation between the results of these investigations and the radiological stage of the mediastino -pulmonary disease. Steroid therapy was instituted in 68 p. 100 of cases. The outcome with or without therapy was favourable in 82 p. 100 of cases, confirming the usually benign course of sarcoidosis when the heart is not involved.

Adolescent↗