Biomedical subjects
Publications and source records attributed to E Ciambellotti.
Sequential computerized hepatobiliary imaging was performed in 11 jaundiced patients before, during, and after biliary decompression. The rates of plasma clearances and radionuclide accumulation in liver cells and biliary tree were calculated, in addition to the uptake and retention index.
Construction specifications are given for a hard ray roentgenotherapy device which may be used either for analgesic, antiphlogistic treatment of acute and chronic arthromyopathy or for the treatment of surface or medium depth neoplasias. The advantages of using highly filtered x-rays and the possibility of irradiating at very low DFP are discussed. Applications of this radiotherapeutic method are given.
A sequential scintigraphic technique for the evaluation of liver and spleen granulopexic function is described. The spleno-hepatic uptake index revealed by computerised scintiscanning proved a reliable indicator of moderate and especially severe diffuse hepatopathy. The test is quickly and easily performed and is also practical since it uses the same radioactive bolus injected for static scintigraphy.
Various techniques are described for the electronic processing of myocardial scintigraphic images using 201Thallium taken at various intervals after muscular exertion. The techniques serve to improve image definition and contrast, making them more representative of the physiopathological reality. The advantages and limitations of certain computer techniques for the measurement of radioactive distribution in the left ventricular myocardium are also discussed. Using such techniques it is possible to obtain an objective and comparative assessment of successive images.
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The technique and results of the gastric secretion test using 99mTc-pertechnetate to investigate functional organic gastropathies are described. The test is fairly simple, well tolerated and an alternative to gastric probing. If performed with a computerised gamma chamber it can indicate the volume of the secretion. A rapid scintigraphy will also provide information on intestinal morphology and is useful if such information it not otherwise obtainable. However the real value of the test is in checking the results of pharmacological or surgical treatment.
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Myocardioscintigraphy with 99mTc MDP is patients undergoing protracted treatment with adriblastin led to the discovery that accumulation of the isotope was infrequent in subjects protected with strophanthin and vitamin E, contrary to the position in an earlier series for whom no treatment designed to reduce the cardiotoxic effect of the antiblastic drug had been provided.
Personal experience in the follow-up of 39 patients subjected to bile duct surgery is reported. The results indicated that sequential isotopic cholangiography is less effective as a supplementary examination in the postoperative period by comparison with its use in preoperative diagnosis. It does, in fact, constitute the only possibility of visualising the main biliary pathway in subjects who have been operated for biliodigestive anastomosis, with the exception of invasive methods, such as PTC, itself out of the question in the execution of periodic postoperative controls.
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Some cases of more or less evident reduction in 99mTc MDP take-up by bone subjected to cobalt therapy for skeletal and extraskeletal neoplastic diseases are presented. On the basis of acquired experience, stress is laid on the diagnostic and prognostic importance of correct assessment of bone scintigraphic changes after irradiation treatment. Some pathogenetic theories in this phenomenon are discussed.
An heterogeneous group of 12 patients has been studied with 201thallium myocardial scintigraphy after stress (MSS); has been used an electronic calculator which made it possible to increase the reliability of the method. Eight patients were males, 4 females; the average age were 52.6 years. The 201thallium (1.7-2 mCi) is injected (through a Teflon cannula inserted in the forearm) 1' before the interruption of the stress test on the cycloergometer. After 10' tests are made in AP-LAO and LL view; a second test is carried out after an hour, and, if necessary, after 4-6 hours time. The results are interpreted as: a) positive: absence (++) or obvious defect in perfusion (+); b) negative: normal perfusion (-); c) questionable: activity not significantly reduced (+/-). In some cases, the authors studied correlations and discordances between MSS and clinical, coronarographic and echocardiographic data. It has been considered moreover, the uptake's and release's variations of the radio-isotope in relation with experimental knowledge of myocardial extraction and clearance. We conclude by emphasizing the interest of this method and suggesting some practical considerations: 1) Patients with negative MSS don't need coronarography. 2) Positive MSS, but restricted deficit, good delayed reperfusion, good clinical pharmacological control would permit a delay of coronarography. 3) Clear multiple deficit need coronarography. 4) Usefulness of the MSS for long-term control of the evolution of coronary disease and of patients operated of aortocoronary bypass.
An heterogeneous group of 24 patients has been studied with 201Thallium myocardial scintigraphy after stress (MSS); has been used an electronic calculator which made it possible to increase the reliability of the method. Nineteen patients were males, 5 females; the average age were 51.7 years S.D. = +/- 7.9. The 201Thallium (2 mCi) is iniected through a Teflon cannula inserted in the forearm l' before the interruption of the stress test on the cycloergometer. After 10' tests are made in AP-LAO and LL view; a second test is carried out after an hour, and, if necessary, after 4-6 hours time. The results are interpreted as: a) positive: absence (++) or obvious defect in perfusione (+); b) negative: normal perfusion (-); c) questionable: activity not significantly reduced (+/-). In some cases, the Authors studied correlations and discordances between MSS and clinical, coronarographic and echocardiographic data. Has been considered moreover, the uptake's and release's variations of the radio-isotope in relation with experimental knowledge of myocardial extration and clearance. We conclude by emphasising the interest of this method and suggesting some practical consideration: 1) patients with negative MSS don't need coronarography; 2) positive MSS, but restricted deficit, good delayed reperfusion, good clinical pharmacological control would permit a delay of coronarography. 3) clear multiple deficit need coronarography; 4) usefulness of the MSS for long-term control of the evolution of coronary disease and of patients operated of aorto-coronary bypass.
A vitamin complex of recognized therapeutic activity in mesenchymal degenerative processes was administered to women suffering from fibrocystic mastopathies. The clinical results and alterations to the mammographic picture after two-three months of treatment are reported.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.