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Biomedical subjects

E Cheraskin

Publications and source records attributed to E Cheraskin.

At least 37 records · Page 2Linked to original sources

The improvement in renal function following EDTA chelation and multi-vitamin-trace mineral therapy: a study in creatinine clearance.

One of the most commonly alleged contraindications to the use of (ethylene diamine tetraacetic acid) chelation therapy is possible renal damage. In this experiment, 13 subjects with chronic degenerative disorders and with renal damage were treated with infusions that included EDTA, vitamins, mineral and oral supplements. Following 20 infusions, creatinine clearance significantly improved. This report adds credence to the findings of those physicians who have noted that EDTA is a safe and major therapeutic modality in the treatment of chronic cardiovascular diseases. The patients reported in this experiment represent a small part of a much larger group of several hundred individuals undergoing a series of tests to determine the utility of EDTA therapy in subjects with occlusive vascular disorders.

Arteriosclerosis↗

The effect of intravenous disodium ethylenediaminetetraacetic acid (EDTA) plus supportive multivitamin/trace mineral supplementation upon fasting serum calcium.

A literature search disclosed only very limited published material suggesting that EDTA therapy when given slowly does not seem to derange serum calcium metabolism. This report summarizes the observations of eighty private practice patients treated with EDTA and supportive multivitamin/trace mineral supplementation and its effects upon serum calcium. The evidence indicates that, in general, this form of chelation therapy does not alter serum calcium concentration. Additionally, and perhaps more importantly, the evidence here suggests the so-called high normals declined slightly, the low normals rise slightly, and those in the intermediate range remain unchanged.

Adult↗

Vitamin C and human wound healing.

Clinical studies provide evidence that wound healing in subjects judged not deficient in vitamin C can be significantly accelerated with supplements of this nutrient above the recommended daily allowance (RDA). The authors administered daily dosages of 500 to 3,000 mg., which is roughly 8 to 50 times the RDA of 60 mg., to subjects recovering from surgery, other injuries, decubital ulcers, and leg ulcers induced by hemolytic anemia. Genetic impairment of collagen synthesis has also been observed to be responsive to ascorbic acid supplementation in an 8-year-old boy with Type VI Ehlers-Danlos syndrome. Four grams of ascorbic acid daily produced a significant improvement in the quality of newly synthesized collagen but did not alter that formed prior to the supplementation of C. The combined evidence in this review provides a substantial base for further research, both clinical and experimental trials, concerning the interrelationships between vitamin C and the body's healing potential.

Adult↗

The influence of EDTA salts plus multivitamin-trace mineral therapy upon total serum cholesterol/high-density lipoprotein cholesterol.

For a number of years, the principal attention was accorded total serum cholesterol as a possible predictor of cardiovascular pathosis. More recently, emphasis has been shifted to the high-density lipoproteins (HDL). Now consideration is turning to the ratio of total serum cholesterol to high-density lipoproteins. In fact, it is now stated that a ratio of 4.5 is the ideal combination in terms of cardiovascular health. This report adds credence to this "ideal" ratio for chronic degenerative disorders.

Cardiovascular Diseases↗

Predictive dentistry: a study in carbohydrate metabolism.

The virtues of prediction in the so-called health sciences are well-known. There is still small but burgeoning interest in predictive medicine; little has been done in predictive dentistry. The evidence presented in this report suggests that carbohydrate metabolism may be utilized as a predictive instrument in dentistry. While the emphasis in this document rests on biochemical techniques, there are other avenues, physiologic ones, such as photomotogrammetry, which can also be used. It is hoped that these paradigms will catalyze interest in this fascinating subject and generate research by others along these lines.

Blood Glucose↗

The relationship of subtle differences in fasting blood glucose with subtle differences in the electrocardiogram: a study of the PR interval.

There are now well-established relationships between the trinity of classical diabetes mellitus, defined cardiovascular syndromes, diverse overt electrocardiographic patterns. What has not been considered is the possible relationship of the subtle forms of prediabetes (meaning nonspecific patterns of carbohydrate metabolism) and subtle expressions of electrocardiographic aberration. The evidence presented herein suggests a real and significant parallelism between the PR interval and small differences in fasting blood glucose not previously reported. Additionally, the data suggest that while it may be normal (average) for the PR interval to increase with advancing age, it is not normal (physiologic) for the PR interval to enlarge in the autumnal years.

Adolescent↗

Tissue tolerance to orthodontic banding. A study in carbohydrate metabolism.

Tissue tolerance to orthodontic banding was determined in a group of children in the Department of Orthodontics at the University of Alabama School of Dentistry. Nonfasting blood glucose and three oral parameters--gingival state, clinical tooth mobility and labial debris--were determined before banding a mandibular lateral incisor and again one month later. Each subject received a multivitamin-trace mineral supplement or an indistinguishable placebo during that month. In the placebo group, statistically significant blood glucose variability (variance) was found in those whose periodontal state was made worse by the orthodontic band. However, a very homeostatic pattern of blood glucose values was displayed by those whose gingival state, tooth mobility, and labial debris improved or remained the same in the presence of the band. Thus, blood glucose variability or homeostasis is one possible way to predict or measure the elusive factor that has been called tissue tolerance.

Blood Glucose↗

Serum cholesterol and the aging process.

With advancing age, the average serum cholesterol level rises. Thus, older persons generally have higher cholesterol scores than do younger individuals. Quite apart, it is a generally agreed fact that older persons die more readily than younger people. Finally, there is general agreement that older persons with higher cholesterol levels die more readily, though not necessarily of cardiovascular disease, than older people without hypercholesterolemia. It then follows that, all other factors being equal, lowering hypercholesterolemia is, in fact, an expression of "making people younger". Two hundred and twenty-one routine private practice patients were studied before and after approximately two months of routine therapy including EDTA treatment and general supportive care including multivitamin-trace mineral supplementation. The evidence indicates, within the limits of this kind of study conducted in a private practice environment, that favorable changes occurred in serum cholesterol levels suggesting a possible reversal of the aging process.

Adult↗

Nutritional aspects of urolithiasis.

Although there is much concern about the relationship between vitamin C consumption and oxalate or uric acid lithiasis in the urinary tract, there is no controlled clinical study that demonstrates this occurrence. Equal concern should be accorded the other nutritional links to urinary lithiasis, since it is very unlikely that vitamin C or any one of the other factors is ever the sole cause of a kidney stone. The rare persons who, because of an altered metabolism, convert much of the ingested vitamin C into oxalic acid constitute the only high-risk category. If the other known nutritional variables were also investigated in these metabolically crippled persons, it might be possible to reduce or eliminate their risk from the intake of vitamin C.

Adult↗