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Biomedical subjects

E Carlsson

Publications and source records attributed to E Carlsson.

154 records · Page 9Linked to original sources
PubMedDate not supplied

A method for the study of regional ischemic dysfunction in the intact dog. Permanent endocardial markers and the pressure-length loop.

A radiographic method for use in the closed-chest dog is described which allows the quantitation of segmental mechanical performance. Previous work has shown that the area of the pressure-length loop (an approximation of a stress-strain integral) is a useful measure of the mechanical work performed by a segment of myocardium. The position of radiopaque markers previously placed to define segments of myocardium is recorded by biplane cineradiography. From simultaneous measurements of left ventricular pressure the integral of pressure with respect to segment length during one cardiac cycle is calculated. An example illustrating the utility of this model for the study of regional myocardial ischemia is presented.

Animals↗
PubMedDate not supplied

The effects of orientation on volume measurements of human left ventricular casts.

Biplane angiocardiography has emerged as a standard method for calculating left ventricular volume measurements. Validation of such measurements has separately been made for several projections of silicone casts of the left ventricle. This study was undertaken to establish and compare the regression lines for left ventricular cast volume measurements in the commonly used angiographic projections. Once established, any ventricular volume can be calculated from the slope and intercept of the regression line obtained from the appropriate angiographic projection.

Angiocardiography↗
PubMedDate not supplied

Assessment of human right ventricular cast volume by CT and angiocardiography.

Angiocardiographic methods available for cardiac chamber volume measurements have been shown to be less accurate although more practical than CT for the evaluation of the LV. To explore the capability of CT for RV volume measurements, silastic casts of seven normal RV were measured by a displacement method, conventional angiocardiographic biplane methods, and CT. The displacement method used degassing beneath vacuum to remove air trapped in the casts, and the actual volumes, which varied between 62 and 188 cc, were measured by Archimedes' principle. Cast volumes measured by biplane angiogram methods displayed a varying degree of spread around the regression line, caused by the chamber's irregular shape and its variation in orientation relative to the x-ray beams. CT measurements were in all aspects significantly more accurate.

Angiocardiography↗
PubMedDate not supplied

Detection of myocardial infarction in dogs by contrast enhanced sequential CT scans.

Surgically induced myocardial infarcts were studied in ten dogs by contrast enhanced computer transmission tomography at several stages of the infarct evolution. The hearts were scanned sequentially at 3.4 second intervals during intravenous bolus injection of contrast medium and every five minutes following the completion of a ten minute contrast medium infusion. Cardiac borders including those of the infarctions were defined by computer graphic techniques. Data from several consecutive scans were combined into one image; the ventricular chamber boundaries and those of the epicardium were reconstructed from images taken during the bolus injection. Images taken during the contrast medium washout phase were used for infarct area determination. A statistical definition of the boundary between normal tissue and infarcted myocardium was obtained which correlated well with autopsy measurements. Image analysis as described here may serve as a basis for infarct volume estimates as well as differentiation between acute and chronic infarctions.

Animals↗
PubMedDate not supplied

Branch clinics.

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