[The Nissen fundus gastroplication combined with parietal cell vagectomy in the surgical treatment of hiatal hernia].
Explore the source record for details and available documents.
Adult↗
Biomedical subjects
E Carbonell
Publications and source records attributed to E Carbonell.
[Are symbolic behaviour and neuroplasticity an example of gene-culture coevolution?].
INTRODUCTION AND DEVELOPMENT: The brain size in the Homo genus not only has not increased during the last 150,000 years but has also experienced a slight reduction in the last 35,000 years. This reduction coincides with the generalization of the symbolic culture that was most likely established during the Upper Palaeolithic. Therefore, the cognitive capacities characteristic in the Homo sapiens could be due to structural and functional changes during the brain evolution, rather than an increase of the brain size. Dependence of symbolic culture probably required an increase of the learning and memory skills, thus demanding, at the same time, an improvement of neuroplasticity. CONCLUSIONS: The epsilon3 and epsilon2 alleles of the apolipoprotein E seem to contribute to a better synaptic repairing, in relation to the ancestral epsilon4 allele. Mutation leading to the epsilon3 allele occurred between 220,000 and 150,000 years ago. Its selection and expansion may have continued until a relatively recent period that coincides with the emergence and expansion of the complex symbolic culture. Other factors favouring neuroplasticity, such as certain polymorphisms and the expression increase of certain proteins as reelin, could also have been selected. Emergence of the symbolic behaviour and increase of its deriving technical and social complexity could have made an intense selective pressure leading to a selection of genes that induced an improvement in neuroplasticity. This would constitute an example of gene-culture coevolution.
Alleles↗
[5 years' experience with parietal cell vagotomy].
The authors presents five years experience with the Parietal Cell Vagotomy in 65 cases. In this group 54 of them had duodenal ulcer, 7 cases presented duodenal ulcer and Hiatal hernia. Only 4 cases presented hiatal hernia. Clinical, radiological and gastric secretion controls show a satisfactory evolution and considerable reduction in the ion H+ concentration. The authors presented in their series 4.6% recurrence in the D.U. group, the morbidity was 1.5%, they did not report operative mortality.
Adolescent↗
Genotoxic evaluation of the herbicide paraquat in cultured human lymphocytes.
The widely used herbicide paraquat was evaluated for genotoxicity in peripheral blood human lymphocyte cultures. Sister-chromatid exchanges (SCE), chromosome aberrations (CA), and micronuclei (MN) were scored as genetic endpoints. Paraquat was administered either alone or in combination with an external source of metabolic activation. Our data indicate that paraquat induced slight but significant increases in the frequency of SCE. This genotoxic effect was not modified by cotreatments with S9 fraction from rat liver. However, paraquat did not increase the frequency of CA and MN, indicating that this bipyridylium compound is not effective in these assays, which would mean a general lack of effectiveness of the herbicide to induce clastogenic damage. In addition, cotreatments with the S9 fraction, did not modify the genotoxic ability detected in the SCE assay.
Animals↗