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Biomedical subjects

E Campos

Publications and source records attributed to E Campos.

At least 73 records · Page 4Linked to original sources

[Plasma levels of apoproteins B and A in relation to blood cholesterol and triglycerides. Distribution according to age and sex and influence of various risk factors (author's transl)].

Plasma levels of apoproteins B and A, triglycerides, VLDL + LDL-cholesterol and HDL-cholesterol were simultaneously measured in an ambulatory population of 477 subjects (206 male and 271 female). VLDL + LDL-cholesterol and apo B values were similar in males and females and significantly increased with age. Conversely, HDL-cholesterol and apo A values were higher in females than in males and remained stable with age. HDL-cholesterol and apo A correlated inversely with triglycerides. Overweight, alcohol and smoking introduced significant changes in the parameters studied.

Adolescent↗

Plasma levels of VLDL- + LDL-cholesterol, HDL-cholesterol, triglycerides and apoproteins B and A-I in a healthy population--influence of several risk factors.

Plasma apo B and apo A-I were determined in 477 subjects (206 males and 271 females) by laser immuno-nephelometry. Measurements of VLDL- + LDL-cholesterol, HDL-cholesterol and triglycerides were done simultaneously. VLDL- + LDL-cholesterol and apo B values were similar in males and females and increased with age. HDL-cholesterol and apo A-I values were higher in females but stable with age. Different regression curves (HDL-cholesterol vs apo A-I) were obtained in males and females and a negative correlation was found between HDL-cholesterol or apo A-I and triglycerides. Increased body weight was associated with higher values of VLDL- + LDL-cholesterol, apo B and triglycerides in both sexes but lower values of HDL-cholesterol and apo A-I essentially in males. Finally, the study provides evidence of a relationship between smoking and alcohol consumption on the one hand, and HDL-cholesterol and apo A-I on the other.

Adult↗

Isolation and characterization of multiply antibiotic-resistant Clostridum perfringens strains from porcine feces.

Multiply antibiotic-resistant strains of Clostridium perfringens were isolated from porcine feces. Strains that were resistant to tetracycline, erythromycin, clindamycin, and lincomycin were isolated, but no penicillin- or chloramphenicol-resistant strains were obtained. Typical minimal inhibitory concentrations for resistant strains were 16 to 64 mug of tetracycline per ml, 64 to >128 mug of erythromycin per ml, >/=128 mug of lincomycin per ml, and 16 to 128 mug of clindamycin per ml. Resistance to erythromycin was always associated with resistance to lincomycin and clindamycin. Minimal inhibitory concentrations were determined for 258 strains from six farms that used antibiotics in their feeds and 240 strains from five farms that did not use antibiotics. The results show that 77.9 and 22.7% of the strains from the former farms were resistant to tetracycline and erythromycin-clindamycin-lincomycin, respectively. The comparable data from the latter farms were 25.0 and 0.8%, respectively. Agarose gel electrophoresis failed to reveal a plasmid band that was common to the resistant strains but absent in the susceptible strains. Attempts to transfer tetracycline, erythromycin, and clindamycin resistance from one strain, CW459, were not successful. Antibiotic-susceptible mutants were not isolated from this strain, despite the use of a variety of curing agents.

Animals↗

14 cases of cavernous degeneration of the optic nerve.

After a brief bibliographical introduction the author's report on 14 cases of cavernous degeneration of the optic nerve, based upon the study of 1,831 autoptic cases. All the subjects examined showed lesions of a senile degenerative type in the vessels afferent to the retro-laminar segment of the optic nerve. The pathogenetic mechanism of the lesion under examination seems therefore to be attributable to ischaemic cause of a chronic type. Myopia and glaucoma, if present, would also seem to contribute, as they cause disorders of the blood system in this region.

Aged↗

[Areas of anomalous binocular single vision in small angle concomitant esotropia: evaluation by means of a modification of the v. Graefe technique (author's transl)].

A red filter in front of the fixing eye according to the v. Graefe technique was used in order to detect binocular visual field in patients with anomalous retinal correspondence and small angle esotropia. A striated glass was also placed in front of the deviated eye, in order to check whether single perception was related to suppression or to binocular vision. It has been demonstrated that these patients prevalently enjoy an anomalous binocular vision supported by an anomalous retinal correspondence. The suppression scotoma described by the v. Graefe perimetric technique may therefore in certain cases be in reality areas of single anomalous binocular vision. It has also been seen anomalous retinal correspondence is more deeply rooted at the center than at the periphery of the binocular visual field.

Adolescent↗

Sonographic-radiographic correlations of renal and perirenal infections.

Sonograms of 43 patients with intrinsic and perirenal infectious processes are reviewed. Fourteen had acute pyelonephritis; three, suppurative pyelonephritis; two, focal pyelonephritis; six, renal abscesses; three, infected cysts; six, perinephric abscesses; six, pyonephrosis; and three, chronic pyelonephritis. Sonography had little diagnostic value except for the patients with perinephric abscess. However, it proved valuable as a guide for a percutaneous approach to obtain cells for histologic diagnosis, to obtain fluid to determine chemotherapy, and to perform antegrade pyelography and percutaneous nephrostomy.

Abscess↗

Tick-borne tularemia. An outbreak of lymphadenopathy in children.

Between June 1 and July 15, 1984, twenty persons with glandular tularemia were identified on the Lower Brule and Crow Creek Indian reservations in South Dakota. The median age of the patients was 6 years (range, 2 to 20 years). The clinical illness was mild, consisting of fever, headache, and lymphadenopathy. All lymphadenopathy was in the head and neck area. Dermacentor variabilis ticks were identified as the vector. Although the mild clinical illness suggested Francisella tularensis, type B, was the agent, both type A and type B strains of F tularensis were isolated from ticks collected from dogs in the area. Tularemia is generally thought to be a severe systemic illness in North America. This outbreak illustrates that it can be a mild disease and that both type A and type B strains can be tick-borne and coexist in the same ecosystem.

Adolescent↗

Amblyopia.

Over the past thirty years, much has been learned about the physiological basis for amblyopia. For many years amblyopia was considered to be a retinal disorder; it has now been well established through animal studies that amblyopia represents functional and morphological effects of visual deprivation on the visual cortex and the lateral geniculate nucleus. With this knowledge has come the recognition of a "sensitive period" of development of the visual system, during which time visual deprivation causes amblyopia. The best approach to managing amblyopia is to detect amblyogenic factors before the age of two years and prevent it through eliminating the causes of visual deprivation. When amblyopia exists, it can be cured if adequately treated in children less than 6-7 years of age. Even in older patients, visual improvement can be achieved with therapy. Current research is aimed at developing substances and delivery modes that will allow the sensitive period of visual development to be manipulated, increasing the period during which it can develop and enhancing preventative and therapeutic measures. In this review selected literature contributing to current understanding of causes, prevention and treatment of amblyopia is discussed. Although many new treatment modalities have been tried, occlusion still seems to be the most successful therapy.

Amblyopia↗