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Biomedical subjects

E Calderon

Publications and source records attributed to E Calderon.

7 recordsLinked to original sources
PubMed1986

A hospital experiment in teamwork among students, nurses, and administrators.

The adversarial relationships existing in 1982 among medical students, nurses, and hospital staff members were recognized at Hermann Hospital, a private, nonprofit teaching hospital in Houston, Texas, to be potentially detrimental to patient care. A joint communications committee--composed of medical students, faculty members, and hospital and nursing administrators--was developed to identify ways to improve relations between medical students and hospital personnel. The results of the committee's efforts have been an orientation program offered to medical students by the hospital prior to their third-year clerkships; elective workshops for second-year students on skills such as venipuncture, ventilatory management, and physiologic monitoring taught by practicing nurses and other health care personnel; and roundtable seminars for all medical students. Three years after its inception, the committee continues to offer and refine the orientation program and skills workshops. In the authors' opinion, the success of the committee can be attributed to the fact that medical students have been instrumental in directing and evaluating the programs.

Clinical Competence↗
PubMed1978

Antibiotic concentrations in pus and bone of children with osteomyelitis.

Pharmacologic data are presented on 39 children treated for osteomyelitis with one of the following antibiotics: methicillin, dicloxacillin, cephaloridine, or cefazolin. The concentrations of drug in pus and bone were correlated with serum concentrations, with the susceptibilities of Staphylococcus aureus strains isolated from the patients, and with the degree of drug protein-binding. The penetration of the antibiotics into pus and bone was similar for the two penicillins and for the two cephalosporins despite the disparate protein-binding affinities of these drugs. The agents attained concentrations in tissues that were at least several fold, and often more than tenfold, greater than the MIC and MBC values of the S. aureus stains. These data provide a basis for selection of antimicrobial agents for treatment of osteomyelitis.

Adolescent↗
PubMed1977

Distinct reovirus-like agents associated with acute infantile gastroenteritis.

Human reovirus-like particles were found by electron microscopy in the stools of 25% of 71 infants and young children hospitalized with acute gastroenteritis in Mexico between December 1976 and April 1977. The virus was also identified by the electrophoresis patterns of its ribonucleic acid upon disruption of partially purified particles. This technique is as reliable as electron microscopy but less laborious, and could become a routine diagnostic procedure. The electrophoretic patterns of viral ribonucleic acid from different cases suggest that there are at least two different reovirus-like agents associated with infantile gastroenteritis.

Acute Disease↗
PubMedDate not supplied

Treatment of presumed bacterial pneumonia in ambulatory children.

In a prospective, randomized, open study, a combination of trimethoprim and rifampin (TMP/R) 20 mg/kg/day was compared with ampicillin (AMP) 150 mg/kg/day, both given orally twice daily for 10 days, for the treatment of 60 children who had mild community-acquired pneumonia. The control group comprised 112 healthy children. The overall duration of the disease was 8.5 +/- 3.6 days in the TMP/R group vs 6.0 +/- 1.1 days in the AMP group. Fever persisted for 7.0 +/- 1.8 days in the TMP/R-treated patients vs 5.2 +/- 1.0 days in the AMP-treated patients. At the end of the 10 days, nasopharyngeal cultures were negative in all patients in the AMP group and in 25 of the 30 patients in the TMP/R group. These five patients were clinical and microbiologic failures. We conclude that in infants and children with mild community-acquired pneumonia, treatment with AMP for 10 days is more effective than treatment with a combination of TMP/R for clinical cure and eradication of bacterial pathogens.

Ampicillin↗