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Biomedical subjects

E C James

Publications and source records attributed to E C James.

41 records · Page 3Linked to original sources
PubMed1976

The management of traumatic asphyxia: case report and literature review.

Traumatic asphyxia is not as benign as has been indicated in the literature (2, 4) and may represent a life-threatening process. A thorough understanding of the involved pathophysiology coupled with aggressive cardiopulmonary management is essential for patient survival. In cases with severe pulmonary injury, the judicious employment of respirator and PEEP therapy is emphasized.

Asphyxia↗
PubMedDate not supplied

Multifactorial analysis of local recurrences in rectal cancer, including DNA ploidy studies: a predictive model.

DNA ploidy studies were performed in 188 patients operated on for rectal cancer. In order to define different risk groups of patients, a stepwise logistic regression was carried out in 138 patients who underwent abdominal "curative" resections. Thirty-seven variables were analyzed. Although several variables were significant, only three improved the prognostic value: (1) more than three positive lymph nodes (p = 0.0007); (2) macroscopic local tumor invasion (p = 0.01); and (3) DNA ploidy (p = 0.03). Standardized discriminant coefficients were used to obtain a model and format for predicting local recurrences. This is the first time that a predictive model for rectal cancer, using DNA ploidy as a variable, is reported. Based on calculated discriminant values (DV), patients can be divided into three subgroups: (1) low risk for local recurrences (DV < -1.9, n = 56)--local recurrences were observed in two patients (3.6%); (2) moderate risk (DV between -1.9 and -0.6, n = 55)--local recurrences occurred in nine patients (16.4%); and (3) high risk (DV > -0.6, n = 27)--local recurrences occurred in 14 patients (51.8%). This predictive model for local recurrences has much better prognostic value than Dukes' staging (p < 0.0001).

Adult↗
PubMedDate not supplied

Aortic mycotic abdominal aneurysm involving all visceral branches: excision and dacron graft replacement.

A 41 year-old patient with an aortic mycotic abdominal aneurysm involving all visceral branches is presented. Excision and dacron graft replacement involving limbs to the coeliac axis, superior mesenteric, and both renal arteries was accomplished successfully. The rationale for employing dacron material in infected tissue is reviewed. In our opinion, an integral aspect of its usage includes the debridement or removal of the aneurysm in conjunction with prolonged antibiotic coverage postoperatively. The patient is alive and free of apparent infection one year following surgery.

Adult↗