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Biomedical subjects

E Brizzi

Publications and source records attributed to E Brizzi.

47 records · Page 3Linked to original sources

The calibers of the common femoral, popliteal, and posterior tibialis arteries: a statistical investigation in 100 healthy subjects by color Doppler ultrasonography.

One hundred healthy subjects (50 men, 50 women; age range: 18 to 90 years) with no history of occlusive arterial disease of the lower extremities were examined. In each, the principal arteries of the lower extremities were measured by Doppler ultrasound. The difference between the dimensions of the arteries of the right with those of the left was generally not significant, although those of the right were consistently larger. The only exceptions were the common femoral arteries in both sexes and the posterior tibialis arteries in the men, where there was a statistically significant predominance of the right. As compared to those of the females, the arterial calibers of the male subjects were significantly larger (p < 0.01) for all the arteries examined. In both sexes, there was a statistically significant direct relationship between vessel caliber and age. There was no correlation between arterial dimension and body index.

Adolescent↗

The anatomical variables of the sapheno-popliteal junction visualization by radiological and echographic examinations.

Increasing interest on the short saphenous vein has been induced by its employment as autologus graft in arterial surgery and for being held responsible for the onset and development of varicose veins of the lower limbs and postoperative recurrence. These two clinical conditions require a more precise assessment of the short saphenous anatomy and its variables previously described in literature. A verify of the anatomical variations of the sapheno-popliteal junction and of the short saphenous outlet in 528 not randomized limbs was performed in separate groups by the following methods: High Resolution Echography, preoperative ascending Phlebography, preoperative Digital Phlebography, intraoperative Selective Phlebography. A high number of anatomical variations was found (29.8%) and the conclusion was that modest differences between published data by other Authors and the results of this study were found. The ideal diagnostic approach for these anatomical variations is the intraoperative Selective Phlebography in cases systematically selected by preoperative High Resolution Echography.

Humans↗

The blood-flow velocity analysis as a possible method for arterial calibre discovery. A statistical investigation in 108 human subjects by color-Doppler method.

Using Echocolordoppler, we have examined 108 subjects with stenosis of the Internal Carotid Artery (ICA). For each subject, age, sex, body weight, height, systolic and diastolic arterial pressure, as well as measures of original caliber of ICA, residual lumen and maximal systolic velocity (MSV) at the stenosis were recorded. In both sexes there was a highly significant correlation (p < 0.001) between MSV, percentage of stenosis, and residual lumen, while there was no correlation between MSV and arterial pressure, which could have modified interpretation of data. Linear regression analysis was performed to calculate total vessel caliber, whenever not directly measurable, from MSV and residual lumen.

Aged↗

The inner diameter of human intracranial vertebral artery by color Doppler method.

In 50 healthy subjects the internal diameter of the intracranial vertebral artery were measured by echocolor doppler method. The diameter of left vertebral a. was greater than that of the right in most subjects (58%); the mean left/right difference was statistically significant (p < 0.05). Analyzing men and women separately, the difference remained significant only in women (p < 0.05). A significant correlation was found between vertebral a. diameter and sex (p < 0.01). The vertebral a. diameter had a tendency to increase with age, that reached significance only for the left vertebral one. No significant correlation was found between body surface area and vertebral a. diameter.

Adolescent↗

Collateral circulation in occlusion of lower limbs arteries: an anatomical study and statistical research in 35 old subjects.

The collateral circles formed following lower limbs arterial occlusion and their hemodynamic function have been described; 35 subjects (23 men and 12 women; age range 65 to 80), with symptomatic lower limbs obstructive arteriopathy (Fontaine's stage II) following occlusion of vessels downstream the subrenal aorta have been studied by means of Contrast Angiography and Color Doppler Echography of the vascular district including the terminal aorta and the lower limbs arteries. The hemodynamic significance of the collateral circles was assessed by calculating the Windsor index. In this population, the collateral circles for each level of obstruction were explored. Occlusion of the terminal abdominal aorta: the collateral circle was mainly established through the inferior mesenteric and ischiatic arteries and through the lumbar, ilio-lumbar and gluteal arteries; occlusion of the iliac tract: the collateral circulation was established through the spermatic or ovaric artery and through the funicular, external pudendal and middle sacral arteries; occlusion of the ilio-femoral tract: the collateral circulation was formed by the internal and external pudendal arteries and by the ilio-lumbar, obturating, gluteal and circumflex iliac arteries; occlusion of first tract of the superficial femoral artery: collateral circulation was established through the deep femoral artery and through the perforating arteries; occlusion of the terminal tract of the superficial femoral artery: collateral circulation was formed by the articular branches of the same artery originating proximal to the occlusion and through branches of the deep femoral artery; occlusion of the superficial and deep femoral arteries at their origin: collateral circulation was established through the ischiatic artery (directly and, indirectly, through the perforating arteries), and through the tegumental arteries. The hemodynamic significance, as measured by Windsor index was higher the more proximal was the occlusion, in accord with the lower caliber and/or number of vessels involved in the collateral circles.

Aged↗

Magnetic resonance angiographic evaluation of circulus arteriosus cerebri (circle of Willis): a morphologic study in 100 human healthy subjects.

The Circle of Willis was studied by Magnetic Resonance Angiography in 100 healthy subjects. In 41% of these cases, the arteries were arranged in the classically described way. In 21%, hypoplasia of the posterior communicating as. was noted, while in 13% the posterior cerebral as were found to originate from the internal carotid a.. In 9% of these cases, three anterior cerebral as. were present. In 3% the anterior communicating artery could not be identified, while the left posterior communicating artery was hypoplastic. In 2% the absence of a posterior communicating artery was associated with the origin of a posterior cerebral a. from the internal carotid. In another 2% the anterior cerebral as. were partially fused, and in yet another 2%, hypoplasia of both an anterior and a posterior cerebral a. was present. The remaining seven cases (7%), all different from each other, represented combinations of the above described variations. Statistical analysis indicated that anomalies occurred more commonly on the left than on the right side. The morphology of the Circle of Willis could not be correlated with either sex or Body Index.

Adult↗

Morphometric evaluation of the symphysis pubis joint.

The Symphysis Pubis (SP) joint was investigated by X-ray in 96 adults without any history of disease of the joints. We evaluated the width of this joint by measuring the distance between the two articular surface at three points. We calculated the mean for the three interpubic distances and carried out statistical analysis so as to evaluate if there is a significative difference between the four age classes (< 50; 50-59; 60-69; > 70) and between males and females. We did not found statistically-significative differences between males and females, and between the age classes; nevertheless, it is to be noted that a slight widening of the SP joint can be seen in the elderly, which is thus not significant. We also noted that the medium part of the SP joint undergoes a larger widening in older people: this is probably due to degenerative changes in the fibrocartilagineous disc and the ligaments.

Aged↗

Collateral circulation in distal occlusion of lower limb arteries: an anatomical study and statistical research in 40 elderly subjects by echo-color-Doppler method.

The collateral circles and their hemodynamic significance in distal lower limb arterial occlusion have been described in an elderly population. Overall 40 subjects (20 men and 20 women; age range 66-83) with symptomatic lower limb arteriopathy (Fontaine's stage II) have been studied combing Contrast Angiography and Color Doppler Echography of the lower limb arterial district. In our population, the results showed that the tibialis arteries were the vessels most often involved in arterial occlusion (posterior tibialis a., 15 cases = 37.5%, posterior tibialis a., 12 cases = 30%), followed by the peroneal a. (8 cases = 20%) and by the popliteal a. (5 cases, 12.5%). In the occlusion of the popliteal artery the collateral circle was mainly established through the deep femoral a., the great anastomotic a., the recurrent posterior tibialis a., and from the articular supero-lateral a. In the occlusion of the anterior tibialis artery the collateral circulation was ensured through the collateral posterior tibialis as. and through the collateral perineal as. In the occlusion of the posterior tibialis a., the collateral circle was established through the great anastomotic a., through the branchers of the arterial circle of the ankle and from the perforating plantar as. (anterior tibial a.). Finally, in the occlusion of the peroneal a., the collateral circulation was only represented by branches of the arterial circle of the ankle. The hemodynamic compromission, measured by the Windsor Index, was the highest for popliteal occlusions (mean IW = 34.3%). Occlusions of the anterior tibialis a. (mean IW. = 35.48%), of the peroneal a. (mean IW = 44.71%), and of the posterior tibialis a. (mean IW = 55.44%) showed progressively lower hemodynamic compromission. Gender differences in hemodynamic significance at each level of occlusion were not significant.

Aged↗

Morphometric analysis of the sacroiliac joint.

The sacroiliac (SI) joint is the point of articulation between the sacrum and the innominate bone of the pelvis. The anterior portion is synovial, and the posterosuperior portion is a typical syndesmosis. The SI joint may be affected by inflammatory or degenerative changes which include narrowing, minor sclerosis and erosion. Alterations in the anatomy of this joint may be involved in causing lower back pain. Radiodiagnosis of the width of the articular space is one of the tools utilized to evaluate the normal state of any joint. Scanty data is available on the morphometric characteristics of the SI joint. Therefore, the articular width space of the SI joint was measured to define its normal size in relation to age and sex. The study included 198 x-rays of the abdomen, in anteroposterior projection, of 112 males and 86 females (age range: 17 to 91 yrs). Individual films were divided into four classes according to age (< 50; 50-59; 60-69; > 70). The articular space of the SI joint is made up of a lateral and a medial part: the first representing the anterior articular space; the latter the posterior one. The anterior articular space of both the right and left joint, which was more easily visible and measurable was measured at the medium and inferior levels. Measurements were taken from the radiograms using a semiautomatic computerized system (Videoplan II, Image Analysis system-Kontron). The mean value of the articular space width a the medium and inferior levels, according to age group, was measured in both the males and females. The values obtained were studied using variance analysis. No significant differences were found in the mean values of the articular space width at the SI joint, when males and females were compared in relation to age. Moreover, the articular space width diminished with increasing the age. This fact was not always statistically significant.

Adolescent↗

Morphometric analysis of the acromioclavicular joint.

The width of the articular space of the acromioclavicular (AC) joint was investigated to evaluate normal range values and any possible variations in relation to age and sex. Radiographs of the AC joints of 72 males and 28 female (age range: 38-83 yrs) were studied. The articular space width of the AC joint was measured using a semiautomatic computerized system. The measurements were performed bilaterally at the level of smallest distance between the articular surfaces in all the radiograms. The mean value of the articular space width was calculated for all the subjects as a single group, for that of the males and for that of the females. The films were then divided into four groups according to age (< 50; 50-59; 60-69; > 70 yrs) and the mean value per group was calculated. The values obtained were studied using variance analysis. No significant difference were found in the mean values of the articular space width when males and females were compared as regards to age. However, even if the articular space width diminished, in both sexes, with an increase in age, the differences between age classes were not statistically significant.

Acromioclavicular Joint↗

Anatomical-radiological and morphometric analysis of the lateral atlantoaxial joint.

The width of the articular space of the lateral atlantoaxial joint was measured to evaluate normal range values and possible variations according to age and sex. The study was based on X-rays of the lateral atlantoaxial joint of 52 females (age range: 18-82 ys) and 50 males (age range: 20-82 ys). The radiograms were taken using a semiautomatic computerized morphometric system (Videoplan II, Image Analysis system-Kontron, Munich, Germany). The articular space width of the lateral atlantoaxial joint was measured on both sides, at the medial, lateral and median levels. The mean value at these levels, on both sides, was calculated. Regression analysis was performed to evaluate the relationships between the width of the articular space at the three different levels and the patient's age and gender. No significant differences were found in the mean values of the articular space width at the three levels as regards gender. However, a significant inverse correlation was found between the articular space width and the patients' age in both males and females. Comparative analysis of regression lines showed that the slope of these lines was not significantly different when the sexes were compared. On the contrary, the intercept of the regression lines at the medial and median levels was significantly higher in the females than in the males; the contrary was encountered at the lateral level. This feature is probably due to the different types of inclination of the articular facets of the axis or of those of the atlas in the two sexes.

Adolescent↗